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Neuroglobin Proteins (NGB)

NGB encodes an oxygen-binding protein that is distantly related to members of the globin gene family. Additionally we are shipping Neuroglobin Antibodies (83) and Neuroglobin Kits (51) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NGB 69237 Q99ME9
NGB 58157 Q9NPG2
NGB 85382 Q99JA8
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Top Neuroglobin Proteins at

Showing 10 out of 22 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
Yeast Macaca mulatta His tag   1 mg Log in to see 56 to 66 Days

NGB Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
Human , ,
, , ,
Rat (Rattus)

Top referenced Neuroglobin Proteins

  1. Human Neuroglobin Protein expressed in Wheat germ - ABIN1312525 : Powers: p53-mediated apoptosis, neuroglobin overexpression, and globin deposits in a patient with hereditary ferritinopathy. in Journal of neuropathology and experimental neurology 2006 (PubMed)

More Proteins for Neuroglobin (NGB) Interaction Partners

Mouse (Murine) Neuroglobin (NGB) interaction partners

  1. Data show that the neuroglobin (Ngb) protein was downregulated in the retinal ganglion cells after optic nerve injury.

  2. Overexpression of neuroglobin reduced sensorimotor deficits following TBI (show TBPL1 Proteins). An endogenous increase in neuroglobin expression occurs during the subacute period. Increasing neuroglobin expression during the acute period after TBI (show TBPL1 Proteins) may improve recovery.

  3. reflect lesser perturbations produced by acute inhalation of combustion smoke in the Ngb overexpressing mouse, suggesting that Ngb mitigates mitochondrial dysfunction and neurotoxicity and raises the threshold of smoke inhalation-induced brain injury

  4. A critical role for neuroglobin is demonstrated via its differential interaction with phosphatase and tensin homolog (PTEN) and Akt during neurite induction.

  5. Neuroglobin overexpression resulted in a significant reduction in infarct volume 24 hours after brain ischemia.

  6. Ngb overexpression can inhibit oxygen-glucose deprivation-induced mitochondria permeability transition opening in primary cultured mouse cortical

  7. CREB (show CREB1 Proteins) may also mediate transcriptional regulation of neuroglobin gene.

  8. Ngb deficiency neither affected the level of Melanopsin (show OPN4 Proteins) and Tyrosine Hydroxylase (show TH Proteins) proteins nor the intactness of PACAP (show ADCYAP1 Proteins)-positive retinohypothalamic projections in the suprachiasmatic nucleus.

  9. This study demonistrated that Ngb over-expression reduced traumatic lesion volume.

  10. mitochondria distribution of Ngb is clearly associated with and may contribute to Ngb's neuroprotection.

Human Neuroglobin (NGB) interaction partners

  1. Study characterized the presence of Ngb (show GTPBP4 Proteins) in the human cochlea

  2. Data show that the mean peak serum neuroglobin and Nogo-A (show RTN4 Proteins) concentrations were both significantly higher in patients with an unfavorable outcome at 6 months after traumatic brain injury (TBI (show TBPL1 Proteins)).

  3. Neuroglobin player role in estrogen receptor alpha (show ESR1 Proteins)-positive cancer cell viability.

  4. a mechanism for redox control of human Ngb (show GTPBP4 Proteins) (hNgb) activity

  5. 17beta-estradiol-induced NGB (show GTPBP4 Proteins) up-regulation could act as an oxidative stress sensor, which does not oppose to the pro-apoptotic 17beta-estradiol effect in ER beta (show ESR2 Proteins)-containing colon cancer cells unless a rise of oxidative stress occurs.

  6. first X-ray structure of wild-type human neuroglobin is reported at 1.74 A resolution

  7. Glu60 of human Ngb (show GTPBP4 Proteins) is a crucial residue for its GDI and neuroprotective activities

  8. Data show that chimeric neuroglobin and myoglobin (show MB Proteins) were generated by swapping a regulatory segment.

  9. This paper for the first time presents the data on neuroglobin distribution in human cerbellum using immunohistochemistry.

  10. Findings indicate that myoglobin (Mb (show MB Proteins)) and neuroglobin (Ngb) can be expressed in nonmuscle and non-neural contexts.

Pig (Porcine) Neuroglobin (NGB) interaction partners

  1. Constitutive expression levels of neuroglobin in neonatal brain cells may explain mild neuronal injury after 60 min. of deep hypothermic circulatory arrest.

Rabbit Neuroglobin (NGB) interaction partners

  1. Ngb overexpression may have potential therapeutic benefits for both reducing secondary damages and improving the outcomes after traumatic spinal cord injury

Zebrafish Neuroglobin (NGB) interaction partners

  1. The zebrafish Neuroglobin can catalyze the reduction of nitrite to nitric oxide with a broad range of reaction rate constants.

  2. Data show that the neuroglobin (Ngb) protein was upregulated in the amacrine cells after optic nerve injury.

  3. Chimeric Myoglobin (show MB Proteins) has a cell-membrane-penetrating activity similar to zebrafish Ngb.

  4. Neuroglobin appears to be associated with mitochondria-rich cell types and thus oxygen consumption rates, suggesting a myoglobin (show MB Proteins)-like function of this protein in facilitated oxygen diffusion

  5. both zebrafish and chimeric ZHHH Ngb can penetrate cell membranes in the absence of Chariot

Neuroglobin (NGB) Protein Profile

Protein Summary

This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions.

Gene names and symbols associated with Neuroglobin Proteins (NGB)

  • neuroglobin (ngb)
  • neuroglobin (NGB)
  • GTP binding protein 4 (Gtpbp4)
  • neuroglobin (Ngb)
  • 2610028C09Rik protein
  • Crfg protein
  • Gtpbp3 protein
  • ngb protein
  • Nog1 protein

Protein level used designations for Neuroglobin Proteins (NGB)

neuroglobin , GTP binding protein 3 , GTP-binding protein NGB , Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB) , chronic renal failure gene protein , chronic renal failure protein , nucleolar GTP-binding protein 1

594898 Xenopus (Silurana) tropicalis
641332 Monodelphis domestica
734191 Xenopus laevis
69237 Mus musculus
58157 Homo sapiens
64242 Mus musculus
85382 Rattus norvegicus
414438 Sus scrofa
414920 Bos taurus
100008868 Oryctolagus cuniculus
100379566 Cavia porcellus
442944 Canis lupus familiaris
428896 Gallus gallus
443260 Ovis aries
641331 Macaca mulatta
100000711 Danio rerio
467518 Pan troglodytes
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