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Neuroglobin Protein (NGB) (AA 1-151, full length) (His-SUMO Tag)

This Recombinant Neuroglobin protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN5710007
$488.40
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Quick Overview for Neuroglobin Protein (NGB) (AA 1-151, full length) (His-SUMO Tag) (ABIN5710007)

Target

See all Neuroglobin (NGB) Proteins
Neuroglobin (NGB)

Protein Type

Recombinant

Origin

  • 9
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Human

Source

  • 9
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Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 90 %
  • Protein Characteristics

    full length, AA 1-151

    Purification tag / Conjugate

    This Neuroglobin protein is labelled with His-SUMO Tag.

    Sequence

    MERPEPELIR QSWRAVSRSP LEHGTVLFAR LFALEPDLLP LFQYNCRQFS SPEDCLSSPE FLDHIRKVML VIDAAVTNVE DLSSLEEYLA SLGRKHRAVG VKLSSFSTVG ESLLYMLEKC LGPAFTPATR AAWSQLYGAV VQAMSRGWDG E

    Purification

    SDS-PAGE
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1-2 mg/mL

    Buffer

    20 mM Tris-HCl based buffer, pH 8.0

    Storage

    -80 °C,4 °C,-20 °C

    Storage Comment

    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target

    Neuroglobin (NGB)

    Alternative Name

    NGB

    Background

    Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell mbranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.

    Molecular Weight

    32.9 kDa

    UniProt

    Q9NPG2
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