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Neuroligin 4, X-Linked Proteins (NLGN4X)

NLGN4X encodes a member of a family of neuronal cell surface proteins. Additionally we are shipping Neuroligin 4, X-Linked Antibodies (38) and Neuroligin 4, X-Linked Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse NLGN4X NLGN4X 100113365  
NLGN4X 57502 Q8N0W4
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Top Neuroligin 4, X-Linked Proteins at

Showing 8 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag Human Neuroligin-4, X-linked, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Log in to see 2 to 3 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
HOST_Human Cells Human ECD,Fc Tag 100 μg Log in to see 16 Days
HOST_Human Human His tag   10 μg Log in to see 11 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_HEK-293 Human His tag   0.1 mg Log in to see 2 to 3 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

NLGN4X Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , ,
, , ,

Top referenced Neuroligin 4, X-Linked Proteins

  1. Human NLGN4X Protein expressed in HEK-293 Cells - ABIN2181539 : Irie, Hata, Takeuchi, Ichtchenko, Toyoda, Hirao, Takai, Rosahl, Südhof: Binding of neuroligins to PSD-95. in Science (New York, N.Y.) 1997 (PubMed)
    Show all 2 references for ABIN2181539

More Proteins for Neuroligin 4, X-Linked (NLGN4X) Interaction Partners

Mouse (Murine) Neuroligin 4, X-Linked (NLGN4X) interaction partners

  1. Nlgn4 KO impairs synaptic inhibition in hippocampal CA3 (show CA3 Proteins) area and perturbs gamma oscillations.

  2. Our findings indicate an absence of autism-relevant behavioral phenotypes in subsequent generations of Nlgn4 mice tested at two locations.

  3. Mice with a loss-of-function mutation in the Nlgn4 exhibit highly selective deficits in reciprocal social interactions and communication that are reminiscent of autism spectrum conditions in humans.

  4. The selectively rapid evolution of NL4 in mice suggests that its function in the brain is under less stringent control than that of other NLs (show ALDH1A2 Proteins).

Human Neuroligin 4, X-Linked (NLGN4X) interaction partners

  1. Endogenous NLGN4X is intensely phosphorylated on T707 upon PKC stimulation in human neurons.

  2. Our data provided a further evidence for the involvement of NLGN3 (show NLGN3 Proteins) and NLGN4X gene in the pathogenesis of autism in Chinese population.

  3. The present study explores, for the first time, the contribution of NLGN3 (show NLGN3 Proteins) and NLGN4X genetic variants in Greek patients with autistic disorder.

  4. In vitro models show NLGN4X knockdown directly impacts neurodevelopmental process during the formation of neurons and their connections.

  5. Lack of association between NLGN3, NLGN4, SHANK2 and SHANK3 gene variants and autism spectrum disorder in a Chinese population.

  6. Neuroligins are adhesion proteins that bind to beta-neurexin (show NRXN1 Proteins) to form functional synapses.

  7. The autism-associated DeltaE4 mutation in NLGN4 compromises the ability of NLGN4 to localize correctly to the cell surface when overexpressed and to induce synaptic differentiation.

  8. results indicate that the genetic variants located in NLGN4 can affect the cognitive abilities of boys.

  9. Results suggest that unique conformational reshaping of the neuroligin 4 surface is required to permit neurexin (show NRXN1 Proteins) 1beta association.

  10. report mutations in two X-linked genes encoding neuroligins NLGN3 (show NLGN3 Proteins) and NLGN4 in siblings with autism-spectrum disorders

Neuroligin 4, X-Linked (NLGN4X) Protein Profile

Protein Summary

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs, large (Drosophila) homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Two transcript variants encoding the same protein have been identified for this gene.

Gene names and symbols associated with NLGN4X

  • neuroligin 4, X-linked (NLGN4X)
  • neuroligin 4, X-linked (nlgn4x)
  • neuroligin 4-like (Nlgn4l)
  • ASPGX2 protein
  • AUTSX2 protein
  • HLNX protein
  • HNL4X protein
  • NL-4 protein
  • NL4 protein
  • NLGN4 protein
  • Nlgn4x protein

Protein level used designations for NLGN4X

X-linked neuroligin 4 , neuroligin-4, X-linked , neuroligin 4, X-linked , neuroligin-4, X-linked-like , neuroligin 4 , Neuroligin-4, X-linked

465474 Pan troglodytes
100018813 Monodelphis domestica
100050709 Equus caballus
100082183 Ornithorhynchus anatinus
100173414 Pongo abelii
100329189 Xenopus (Silurana) tropicalis
100412584 Callithrix jacchus
100600911 Nomascus leucogenys
100113365 Mus musculus
57502 Homo sapiens
428006 Gallus gallus
607406 Canis lupus familiaris
101909915 Bos taurus
100521700 Sus scrofa
574392 Macaca mulatta
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