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Neuroligin 4 Protein (NLGN4) (His tag)

NLGN4 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318817
  • Target See all Neuroligin 4 (NLGN4) Proteins
    Neuroligin 4 (NLGN4)
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 3
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This Neuroligin 4 protein is labelled with His tag.
    Purpose
    Recombinant Human NLGN4X Protein (His Tag)
    Sequence
    Gln42-Ser676
    Characteristics
    Recombinant Human Neuroligin 4, X-Linked is produced by our Mammalian expression system and the target gene encoding Gln42-Ser676 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product NLGN4 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Neuroligin 4 (NLGN4)
    Alternative Name
    NLGN4X (NLGN4 Products)
    Synonyms
    ASPGX2 Protein, AUTSX2 Protein, HLNX Protein, HNL4X Protein, NLGN4 Protein, nlgn4 Protein, NLGN4X Protein, Nlgn4x Protein, neuroligin 4, X-linked Protein, neuroligin-4, X-linked Protein, NLGN4X Protein, nlgn4x Protein, LOC100714631 Protein
    Background

    Background: Neuroligin 4, X-Linked (NLGN4X) is a single-pass type I membrane protein that belongs to the type-B carboxylesterase/lipase family. NLGN4X is detected at higher levels in heart and at lower levels in the liver, skeletal muscle, and pancreas. NLGN4X is a putative neuronal cell surface protein involved in cell-cell-interactions. NLGN4X may act as splice site-specific ligands for β-neurexins. It has been shown that NLGN4X is involved in the formation and remodeling of central nervous system synapses. NLGN4X also interacts with discs, large (Drosophila) homolog 4 (DLG4). Defects in NLGN4X have been associated with autism and Asperger syndrome.

    Synonym: Neuroligin-4 X-Linked, Neuroligin X, HNLX, NLGN4X, KIAA1260, NLGN4

    Molecular Weight
    72.5 kDa
    UniProt
    Q8N0W4
    Pathways
    Cell-Cell Junction Organization, Synaptic Membrane
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