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Pim-3 Oncogene Proteins (PIM3)

The protein encoded by PIM3 belongs to the Ser/Thr protein kinase family, and PIM subfamily. Additionally we are shipping Pim-3 Oncogene Antibodies (29) and Pim-3 Oncogene Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PIM3 415116 Q86V86
PIM3 64534 O70444
PIM3 223775 P58750
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Top Pim-3 Oncogene Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,867.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,876.50
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details
HOST_Baculovirus infected Insect Cells Mouse GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PIM3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Rat (Rattus)

Mouse (Murine) ,
,

More Proteins for Pim-3 Oncogene (PIM3) Interaction Partners

Human Pim-3 Oncogene (PIM3) interaction partners

  1. Pim-3 has a role in human pancreatic cancer cell survival against radiation

  2. A high percentage of urothelial carcinomas express Pim (show PIM1 Proteins) kinases. Pim (show PIM1 Proteins) expression differs in NILG, NIHG, and IHG lesions.

  3. MicroRNA506 participates in pancreatic cancer pathogenesis by targeting PIM3

  4. Pim-3 kinase enhances growth and metastatic properties of prostate cancer xenografts. PC-3 (show PCSK1 Proteins) prostate cancer cells overexpressing either Pim-1 (show PIM1 Proteins) or Pim-3 kinases form larger xenograft tumors than the parental PC-3 (show PCSK1 Proteins) cells.

  5. Knockdown of Pim-3 by specific shRNA slowed decreased proliferation, induced cell cycle arrest in the G0/G1 phase, and increased apoptosis in glioblastoma cells.

  6. PIM3 expression is higher in ovarian cancer than in normal ovarian tissue. Upregulation of PIM3 promotes proliferation and migration of ovarian cancer cells.

  7. Data demonstrate the role of PIM (show PIM1 Proteins) kinases in driving myeloid leukemia (show BCL11A Proteins), and as candidate molecules for therapy against human malignancies.

  8. we constructed a dual-function small hairpin RNA (shRNA) vector containing an shRNA targeting Pim-3 and a TLR7 (show TLR7 Proteins)-stimulating ssRNA.

  9. Blocking the activities of PIM (show PIM1 Proteins) kinases(PIM1 (show PIM1 Proteins), PIM2 (show PIM2 Proteins) and PIM3) could prevent pancreatic cancer development. PIM (show PIM1 Proteins) kinases(PIM1 (show PIM1 Proteins), PIM2 (show PIM2 Proteins) and PIM3) may be a novel target for cancer therapy

  10. cancer development and in promoting tumor neovascularization and subsequent tumor growth. Targeting Pim-3 may play a dual role in halting tumor progression, by promoting tumor cell death and blocking angiogenesis

Mouse (Murine) Pim-3 Oncogene (PIM3) interaction partners

  1. Loss of PIM3 is associated with abnormal hematopoietic phenotypes.

  2. investigation of physiological role of Pim3 in beta-cell function: regulates glucose-stimulated insulin (show INS Proteins) secretion; limits ERK (show EPHB2 Proteins) signaling; interacts with SOCS6 (show SOCS6 Proteins); Pim3 localized to beta-cell; Pim3 knockout mice display increased glucose tolerance

  3. Pim-3 has an important role in modulating c-Myc and PGC-1alpha protein levels and cell growth

  4. All three Pim (show PIM1 Proteins) kinase family members predominantly phosphorylate Bad on Ser112 and in addition are capable of phosphorylating Bad on multiple sites associated with the inhibition of the pro-apoptotic function of Bad in HEK (show EPHA3 Proteins)-293 cells

  5. Pim-3 kinase has a novel role in the control of self-renewal of embryonic stem cells.

  6. Pim-3 is expressed in endothelial cells and promotes vascular tube formation.

Pim-3 Oncogene (PIM3) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis.

Gene names and symbols associated with Pim-3 Oncogene Proteins (PIM3)

  • Serine/threonine-protein kinase Pim-3 (pim3)
  • pim-1 oncogene (pim3)
  • pim-3 oncogene (PIM3)
  • pim-3 oncogene (Pim3)
  • proviral integration site 3 (Pim3)
  • BC026639 protein
  • Kid1 protein
  • pim-3 protein
  • pim1-a protein

Protein level used designations for Pim-3 Oncogene Proteins (PIM3)

serine/threonine protein kinase pim-3 , non-specific serine/threonine protein kinase , serine/threonine-protein kinase pim-3 , serine/threonine kinase Pim-3 , kinase induced by depolarization , protein kinase Kid-1 , proviral integration site 3 , serine threonine kinase pim3 , KID-1/kinase induced by depolarization

GENE ID SPECIES
100194838 Salmo salar
394343 Xenopus laevis
415116 Homo sapiens
64534 Rattus norvegicus
768655 Gallus gallus
100336651 Bos taurus
100722030 Cavia porcellus
223775 Mus musculus
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