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PIKFYVE Proteins

(phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE))
Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. This gene encodes an enzyme (PIKfyve\; also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate. The D-5 position also can be phosphorylated by type I PtdIns4P-5-kinases (PIP5Ks) that are encoded by distinct genes and preferentially phosphorylate D-4 phosphorylated PtdIns. In contrast, PIKfyve preferentially phosphorylates D-3 phosphorylated PtdIns. In addition to being a lipid kinase, PIKfyve also has protein kinase activity. PIKfyve regulates endomembrane homeostasis and plays a role in the biogenesis of endosome carrier vesicles from early endosomes. Mutations in this gene cause corneal fleck dystrophy (CFD)\; an autosomal dominant disorder characterized by numerous small white flecks present in all layers of the corneal stroma. Histologically, these flecks appear to be keratocytes distended with lipid and mucopolysaccharide filled intracytoplasmic vacuoles. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010].
phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) protein (His tag) phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) protein (His tag) phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) protein (His tag) (ABIN2729013)

PIKFYVE Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (AA 1-451) protein (GST tag) phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (AA 1-451) protein (GST tag) phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (AA 1-451) protein (GST tag) (ABIN1315147)

PIKFYVE Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB

phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (AA 342-451) protein (GST tag) phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (AA 342-451) protein (GST tag) phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (AA 342-451) protein (GST tag) (ABIN1315149)

PIKFYVE Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB

PIKFYVE Proteins by Origin

Find PIKFYVE Proteins for a variety of species such as anti-Human PIKFYVE, anti-Mouse PIKFYVE. The species listed below are among those available. Click on a link to go to the corresponding products.

PIKFYVE Proteins by Source

Find PIKFYVE Proteins with a specific Source. The Source listed below are among those available. Click on a link to go to the corresponding products.

PIKFYVE Proteins by Protein Type

Find PIKFYVE Proteins with a specific Protein Type. The Protein Type listed below are among those available. Click on a link to go to the corresponding products.

PIKFYVE Proteins by Application

Find PIKFYVE Proteins validated for a specific application such as WB, AbP, ELISA, STD. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular PIKFYVE Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3011153
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2729011
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2729012
Quantity 20 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7087017
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells, Insect cells (Sf9)
Validations
Cat. No. ABIN6700371
Quantity 50 μg
Datasheet Datasheet

Aliases for PIKFYVE Proteins

phosphoinositide kinase, FYVE finger containing (pikfyve) Proteins
phosphoinositide kinase, FYVE-type zinc finger containing (PIKFYVE) Proteins
phosphoinositide kinase, FYVE type zinc finger containing (Pikfyve) Proteins
phosphoinositide kinase, FYVE-type zinc finger containing (Pikfyve) Proteins
5230400C17Rik Proteins
CFD Proteins
FAB1 Proteins
fab1-like Proteins
p235 Proteins
PIP5K Proteins
Pip5k Proteins
pip5k3 Proteins
PIP5K3 Proteins
Pip5k3 Proteins
Pipk5k3 Proteins
PipkIII Proteins
wu:fo93c03 Proteins
ZFYVE29 Proteins
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