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Receptor for SEMA4D. Additionally we are shipping Plexin B1 Proteins (10) and Plexin B1 Kits (4) and many more products for this protein.
Showing 10 out of 61 products:
Deletion of plexin-B1, the high affinity receptor for semaphorin 4D (show SEMA4D Antibodies), significantly (one-way ANOVA; p < 0.001) reduced thrombus weight (- 40%) in oxidative venous thrombosis.
Sema (show SEMA3B Antibodies) 4D/CD100 (show SEMA4D Antibodies) is not only a ligand for plexin B1 but also a direct signaling receptor in mediating Sema (show SEMA3B Antibodies) 4D/CD100 (show SEMA4D Antibodies)-plexin B's biological functions.
In Erb (show ERBB2 Antibodies)B-2-overexpressing murine breast cancer, ablation of Plexin-B1 genes strongly reduced metastases. Plexin-B1 has no effect on tumorigenesis o (show ERBB2 Antibodies)r tumor growth but is require (show RHOA Antibodies)d for m (show RHOC Antibodies)etastasis of ErbB-2-dependent breast cancers in vivo.
Semaphorin 4D (show SEMA4D Antibodies)-induced nitric oxide synthase (show NOS Antibodies) (iNOS (show NOS2 Antibodies)) and nitric oxide (NO) production are mediated through plexin-B1.
a lack of plexin-B1 did not impact on cortical development in vivo
LARG (show ARHGEF12 Antibodies) plays a critical role in plexin-B1 signaling to stimulate Rho activation and cytoskeletal reorganization.
binding of Sema (show SEMA3B Antibodies) 4D to Plexin B1 stimulates the tyrosine kinase (show TYRO3 Antibodies) activity of Met
Results suggest that plexin-A1 (show PLXNA1 Antibodies) and B1 interact in the adult brain and transduce semaphorin 3A (show SEMA3A Antibodies) signaling in cooperation.
The mechanism of semaphorin D (show SEMA3A Antibodies) in the activation of the MAPK (show MAPK1 Antibodies) pathway via plexin-B1 is reported.
A possible role for plexin-B1 in ovarian follicle growth and steroidogenesis, most likely via the granulosa cells, is suggested.
Plexin-B1 mediates RhoA (show RHOA Antibodies)/integrin alphavbeta3 (show ITGAV Antibodies) involved in the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway and SRPK1 (show SRPK1 Antibodies) to influence the growth of glioma cell, angiogenesis, and motility in vitro and in vivo.
results show that Sema4D (show SEMA4D Antibodies)/plexin-B1 signaling promotes the translocation of androgen receptor (show AR Antibodies) to the nucleus and thereby enhances AR transcriptional activity
Plexin-B1 induces cutaneous squamous cell carcinoma cell proliferation, migration, and invasion by interacting with Sema4D (show SEMA4D Antibodies). Plexin-B1 might serve as a useful biomarker and/or as a novel therapeutic target for cSCC (show CYP11A1 Antibodies).
Results show that decreased expression of Sema4D (show SEMA4D Antibodies), plexin-B1 and -B2 was associated with local recurrence and poor prognosis of breast neoplasm.
Dysregulation of the vascular endothelial growth factor and semaphorin ligand-receptor families in prostate cancer metastasis
Blocking of CD100 (show SEMA4D Antibodies), plexin B1 and/or B2 in adhesion experiments have shown that both CD100 (show SEMA4D Antibodies) and plexins act as adhesion molecules involved in monocyte-endothelial cell binding.
The Semaphorin 4D (show SEMA4D Antibodies)-Plexin-B1-RhoA (show RHOA Antibodies) signaling axis recruits pericytes and regulates vascular permeability through endothelial production of PDGF-B (show PDGFB Antibodies) and ANGPTL4 (show ANGPTL4 Antibodies).
Activation of endogenous plexin-B1 enhances cell migration and tumor invasiveness in prostate cancer cells.
Data indicate that Rnd1 (show RND1 Antibodies) efficiently displaces Rac1 from its complex with Plexin-B1 but not vice versa.
ErbB-2 (show ERBB2 Antibodies) overexpression in human breast & ovarian cancer cell lines leads to phosphorylation & activation of Plexin-B1. This was required for ErbB-2 (show ERBB2 Antibodies)-dependent activation of RhoA (show RHOA Antibodies) & RhoC (show RHOC Antibodies) & promoted invasive behavior.
Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
, plexin b1
, plexin 5
, semaphorin receptor SEP