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anti-Poly-U Binding Splicing Factor 60KDa (PUF60) Antibodies

The protein encoded by PUF60 is a Ro RNP-binding protein. Additionally we are shipping PUF60 Proteins (8) and PUF60 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PUF60 67959 Q3UEB3
PUF60 84401  
PUF60 22827 Q9UHX1
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Top anti-PUF60 Antibodies at

Showing 10 out of 76 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-PUF60 Antibody Titration: 0.2-1 ug/mlPositive Contro... WB Suggested Anti-PUF60  Antibody Titration: 0.5 µg/mL   Positive Cont... 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
Human Goat Un-conjugated ELISA, WB ABIN184855 (1µg/ml) staining of A431 lysate (35µg protein in RIPA buff... 100 μg Log in to see 4 to 5 Days
Cow Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample(30 μg of whole cell lysate) A:Hep G2, B:MOLT4, C: Raji... ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed A43... 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
Human Rabbit Un-conjugated WB PUF60 Antibody (N-term) (ABIN658291) western blot analysis in ZR-75-1 ... 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB ICC/IF Image PUF60 antibody detects PUF60 protein at nucleus by immuno... WB Image Sample (30 ug of whole cell lysate) A: A431 7.5% SDS PAGE ant... 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated EIA, IHC (fro), WB   0.2 mL Log in to see 6 to 8 Days

PUF60 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , , , ,
Rat (Rattus) , , , ,
Human , , , ,
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Top referenced anti-PUF60 Antibodies

  1. Human Polyclonal PUF60 Primary Antibody for IHC, WB - ABIN2779054 : Gao, Li, Feng, Yuan, Wan, Han, Yu: A protein-protein interaction network of transcription factors acting during liver cell proliferation. in Genomics 2008 (PubMed)

  2. Human Polyclonal PUF60 Primary Antibody for EIA, IHC (fro) - ABIN1108798 : Matsushita, Tomonaga, Shimada, Shioya, Higashi, Matsubara, Harigaya, Nomura, Libutti, Levens, Ochiai: An essential role of alternative splicing of c-myc suppressor FUSE-binding protein-interacting repressor in carcinogenesis. in Cancer research 2006 (PubMed)

  3. Human Polyclonal PUF60 Primary Antibody for ELISA, WB - ABIN184855 : Liu, He, Collins, Ge, Libutti, Li, Egly, Levens: The FBP interacting repressor targets TFIIH to inhibit activated transcription. in Molecular cell 2000 (PubMed)

More Antibodies against PUF60 Interaction Partners

Human Poly-U Binding Splicing Factor 60KDa (PUF60) interaction partners

  1. Concomitant over expression of far upstream element (FUSE) binding protein (FBP) interacting repressor (FIR) and its splice variants induce migration and invasion of non-small cell lung cancer cells.

  2. Overexpression of far upstream element (FUSE) binding protein (FBP)-interacting repressor (FIR) supports growth of hepatocellular carcinoma.

  3. High FBP-interacting repressor expression is associated with hepatocellular carcinoma.

  4. The interaction between SAP155 and FIR/FIRDeltaexon2 not only integrates cell-cycle progression and c-Myc transcription by modifying P27 and P89 expression.

  5. Haploinsufficiency of each of SCRIB (show SCRIB Antibodies) or PUF60 contribute uniquely to specific endophenotypes (e.g., coloboma, heart defects), and binary interaction potentially exacerbates other aspects of the clinical pathology of individuals with 8q24.3 deletion.

  6. Circulating FIR (show FARP2 Antibodies) variant mRNA in the peripheral blood of cancer patients were significantly overexpressed compared to that in healthy volunteers.

  7. Data indicate that altered FIR (show FARP2 Antibodies) and c-myc (show MYC Antibodies) pre-mRNA splicing, in addition to c-Myc (show MYC Antibodies) expression by augmented FIR (show FARP2 Antibodies)/FIRDeltaexon2-SAP155 (show SF3B1 Antibodies) complex, potentially contribute to colorectal cancer development.

  8. FIR (show FARP2 Antibodies) is monomeric in solution but dimerizes upon DNA binding; DNA-induced dimerization is mediated by FIR's RNA recognition motif.

  9. study identified PUF60 as a factor that promotes splicing of an intron with a weak 3' splice-site; demonstrated that PUF60 can functionally substitute for U2AF(65)in vitro, but splicing is strongly stimulated by the presence of both proteins

  10. Results describe the roles of the FarUpStream Element (FUSE), FUSE Binding Protein (FBP (show FBP1 Antibodies)), FBP Interacting Repressor (FIR), and TFIIH (show GTF2H1 Antibodies) in the regulation of c-myc (show MYC Antibodies) expression.

PUF60 Antigen Profile

Protein Summary

This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with PUF60

  • poly-U binding splicing factor 60 (Puf60) antibody
  • poly-U binding splicing factor 60KDa (PUF60) antibody
  • 2410104I19Rik antibody
  • 2810454F19Rik antibody
  • FIR antibody
  • RoBPI antibody
  • Siahbp1 antibody

Protein level used designations for PUF60

60 kDa poly(U)-binding-splicing factor , fuse-binding protein-interacting repressor , poly(U)-binding-splicing factor PUF60 , FBP interacting repressor , RNA-binding protein Siah-BP , Ro ribonucleoprotein-binding protein 1 , poly-U binding splicing factor 60K , pyrimidine tract binding splicing factor , siah binding protein 1; FBP interacting repressor; pyrimidine tract binding splicing factor; Ro ribonucleoprotein-binding protein 1 , siah-binding protein 1 , FUSE-binding protein-interacting repressor , Siah binding protein 1

67959 Mus musculus
84401 Rattus norvegicus
22827 Homo sapiens
607245 Canis lupus familiaris
512824 Bos taurus
100174042 Pongo abelii
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