Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2) ELISA Kits

The protein encoded by PLOD2 is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. Additionally we are shipping PLOD2 Antibodies (40) and PLOD2 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse PLOD2 PLOD2 26432 Q9R0B9
Anti-Rat PLOD2 PLOD2 300901  
PLOD2 5352 O00469
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Top PLOD2 ELISA Kits at antibodies-online.com

Showing 1 out of 4 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 2.34 pg/mL 9.375-600 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details

More ELISA Kits for PLOD2 Interaction Partners

Mouse (Murine) Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2) interaction partners

  1. The finding that LH2 modifies collagen in the extracellular space challenges the current view that LH2 functions solely on the endoplasmic reticulum and could also have important implications for cancer biology.

  2. Authors propose that lysyl hydroxylase 2, and the subsequent increase in pyridinoline cross-links, is responsible for the persistent fibrosis in experimental osteoarthritis.

  3. Lysyl hydroxylase-2b directs collagen cross-linking pathways through its action on telopeptidyl lysine residues.

  4. LH2b (show LHX9 ELISA Kits) catalyzes post-translational modification of collagen in collagen matrix formation and mineralization in bone.

  5. analysis of the specific regulation for the expression of LH isoforms as well as for alternative splicing of LH2 during embryogenesis and in different tissues

  6. TIA1 (show TIA1 ELISA Kits) and TIAL1 (show TIAL1 ELISA Kits) regulate the alternate splicing of lysyl hydroxylase 2

Human Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2) interaction partners

  1. This study reports for the first time the expression of PLOD2 in Brain Arteriovenous Malformations and suggests a potential role of PLOD2 in brain Arteriovenous Malformations pathophysiology.

  2. FKBP65 (show FKBP10 ELISA Kits) is linked to pyridinoline cross-linking by specifically mediating the dimerization of LH2.

  3. PLOD2, which is associated with the stiffness of the extracellular matrix, was directly regulated by miR (show MLXIP ELISA Kits)-26a-5p and miR (show MLXIP ELISA Kits)-26b-5p and may be a good prognostic marker in patients with BC

  4. The finding that LH2 modifies collagen in the extracellular space challenges the current view that LH2 functions solely on the endoplasmic reticulum and could also have important implications for cancer biology.

  5. Results show that miR (show MLXIP ELISA Kits)-26a and miR (show MLXIP ELISA Kits)-26b were significantly downregulated in renal cell carcinoma clinical specimens and appeared to function as tumor suppressors through regulation of collagen cross-linking enzymes, LOXL2 (show LOXL2 ELISA Kits) and PLOD2, both of which function as oncogenes in this disease.

  6. findings reveal that TGFbeta1 (show TGFB1 ELISA Kits) induces a SP1 (show PSG1 ELISA Kits)- and SMAD3 (show SMAD3 ELISA Kits)-dependent recruitment of histone modifying enzymes to the PLOD2 promoter other than the currently known TGFbeta1 (show TGFB1 ELISA Kits) downstream co-activators and epigenetic modifications

  7. LH2 enhances the metastatic properties of tumor cells and functions as a regulatory switch that controls the relative abundance of biochemically distinct types of collagen cross-links in the tumor stroma.

  8. TGFbeta (show TGFB1 ELISA Kits) induced PLOD2/LH2 expression in human synovial osteoarthritic fibroblasts through ALK5 (show TGFBR1 ELISA Kits) signaling.

  9. data indicate that HIF-1alpha (show HIF1A ELISA Kits) controls sarcoma metastasis through PLOD2-dependent collagen modification and organization in primary tumors

  10. Infrapatellar fat pad (show PADI4 ELISA Kits) contributeS to the development of synovial fibrosis in the knee joint by increasing collagen production, PLOD2 expression, cell proliferation, and cell migration.

PLOD2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with PLOD2

  • procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 (Plod2) antibody
  • procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2) antibody
  • D530025C14Rik antibody
  • LH2 antibody
  • Plod-2 antibody
  • TLH antibody

Protein level used designations for PLOD2

lysyl hydroxylase 2 , procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 , LH2 , Procollagen-lysine 2-oxoglutarate 5-dioxygenase (Lysine hydroxylase) 2 , Procollagen-lysine, 2-oxoglutarate 5-dioxygenase (Lysine hydroxylase) 2 , lysine hydroxylase 2 , lysyl hydroxlase 2 , telopeptide lysyl hydroxylase , procollagen-lysine 2-oxoglutarate 5-dioxygenase 2

GENE ID SPECIES
26432 Mus musculus
300901 Rattus norvegicus
5352 Homo sapiens
641354 Sus scrofa
533642 Bos taurus
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