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anti-Profilin 2 (PFN2) Antibodies

The protein encoded by PFN2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. Additionally we are shipping Profilin 2 Proteins (29) and Profilin 2 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PFN2 5217 P35080
PFN2 18645 Q9JJV2
PFN2 81531 Q9EPC6
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Top anti-Profilin 2 Antibodies at

Showing 10 out of 75 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PFN2 Antibody (C-term) in Y79 cell line lysates (35ug/lane).This demonstrates the PFN2 antibody detected the PFN2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC (p), WB Anti- Profilin2 antibody, Western blotting All lanes: Anti Profilin2  at 0.5ug/ml WB: Rat Brain Tissue Lysate at 50ug Predicted bind size: 15KD Observed bind size: 15KD 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated WB PFN2 Antibody (C-term)  western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the PFN2 antibody detected the PFN2 protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample(30 ug whole cell lysate) A: A431, B: H1299 12% SDS PAGE antibody diluted at 1:500 IHC-P Image Profilin 2 antibody detects PFN2 protein at cytoplasm on human colon carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded colon carcinoma. Profilin 2 antibody , dilution: 1:500. 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated WB Western blot analysis of Profilin 2 expression in A431 (A), H1299 (B), mouse brain (C), rat skeletal muscle (D) whole cell lysates. 200 μL Log in to see 9 Days
Human Mouse Un-conjugated WB PFN2 monoclonal antibody (M05), clone 6G3. Western Blot analysis of PFN2 expression in HeLa. 0.1 mg Log in to see 8 to 11 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Human K562 cell lysates probed with Anti-Profilin 2 Polyclonal Antibody  at 1:5000 90min in 37˚C. 100 μL Log in to see 3 to 7 Days
Human Chicken Un-conjugated WB E coli-derived fusion protein as test antigen. Affi-anti-PFN2 IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-PFN2 ) 0.05 mg Log in to see 5 to 7 Days
Human Chicken Un-conjugated WB 0.05 mg Log in to see 2 to 3 Days
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days

PFN2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Profilin 2 Antibodies

  1. Human Polyclonal PFN2 Primary Antibody for EIA, WB - ABIN954303 : Shao, Welch, Diprospero, Diamond: Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation. in Molecular and cellular biology 2008 (PubMed)
    Show all 5 references for ABIN954303

More Antibodies against Profilin 2 Interaction Partners

Human Profilin 2 (PFN2) interaction partners

  1. Disease causing mutations in inverted formin 2 (show INF2 Antibodies) regulate its binding to G-actin (show ACTB Antibodies), F-actin capping protein (CapZ (show CAPZB Antibodies) alpha-1 (show CAPZA1 Antibodies)) and profilin 2.

  2. Therefore, this study indicates that profilin 2 affects the metastatic potential and stemness of colorectal CSCs by regulating EMT (show ITK Antibodies)- and stemness-related proteins.

  3. Pfn2 suppresses the recruitment of HDAC1 (show HDAC1 Antibodies) to Smad2 (show SMAD2 Antibodies) and Smad3 (show SMAD3 Antibodies) promoters, increasing their expression, and, in turn, enhancing TGFB1 (show TGFB1 Antibodies) induced epithelial-mesenchymal transformation and VEGF (show VEGFA Antibodies) and CTGF (show CTGF Antibodies) production.

  4. effects of profilin-1 and profilin-2, the two major isoforms of profilin, on actin cytoskeletal regulation, motility, and invasion of breast cancer cells

  5. Oral squamous cell carcinomas with weak PFN2 expression were associated with a significantly worse prognosis than strongly expressed tumours.

  6. These findings raise the possibility that Rgl3 mediates interaction between Ras/Rap-family proteins and profilin II, an important activator of actin polymerization.

  7. A signaling pathway from ROCK1 (show ROCK1 Antibodies) to profilin (show PFN1 Antibodies) controls polyglutamine protein aggregation.

Mouse (Murine) Profilin 2 (PFN2) interaction partners

  1. knockdown of profilin 1 (show PFN1 Antibodies) or profilin (show PFN1 Antibodies) 2a led to significant decrease in cell spreading of astrocytes. the knockdown of profilin (show PFN1 Antibodies) 2a resulted in a significantly reduced morphological complexity of astrocytes in both dissociated and slice culture astrocytes.

  2. Hyper-phosphorylation of profilin2a is the molecular link between SMN (show STMN1 Antibodies) and the ROCK pathway repressing neurite outgrowth in neuronal cells.

  3. Profilin II regulates the exocytosis of kainate glutamate (show GRIN1 Antibodies) receptors.

  4. Phosphatidylinositol 4,5-bisphosphate releases Pfn2 from the Pfn2-dynamin 1 complex as well as from the Pfn2-actin complex, suggesting that Pfn2 is diverging the phosphoinositide signaling pathway to actin polymerization as well as endocytosis

  5. Following NMDA receptor activation profilin 2 accumulates not only in dendritic spines, but also in the nucleus of hippocampal neurons via a process involving rearrangement of the actin cytoskeleton.

  6. results highlight a novel, profilin2-dependent pathway, regulating synaptic physiology, neuronal excitability, and complex behavior

  7. High-resolution structural analysis of mouse profilin (show PFN1 Antibodies) 2a complex formation with two physiological ligands: the formin homology 1 domain of mDia1 and the proline-rich domain of VASP (show VASP Antibodies).

Arabidopsis thaliana Profilin 2 (PFN2) interaction partners

  1. Upregulation of profilin 2 by BFA was verified by immunoblot and live imaging at subcellular level.

Profilin 2 (PFN2) Antigen Profile

Protein Summary

The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.

Gene names and symbols associated with anti-Profilin 2 (PFN2) Antibodies

  • profilin 2 (pfn2) antibody
  • profilin 2 (PFN2) antibody
  • profilin 2 (Pfn2) antibody
  • profilin homolog2 (prf2) antibody
  • profilin-2-like (LOC100621523) antibody
  • Protein PFN-2 (pfn-2) antibody
  • D3S1319E antibody
  • F17A13.170 antibody
  • F17A13_170 antibody
  • PFL antibody
  • Pfn antibody
  • PFN2 antibody
  • PRF2 antibody
  • PRO2 antibody
  • PROFILIN antibody
  • profilin-2 antibody
  • Profilin2 antibody
  • profilin 2 antibody
  • XProfilin2 antibody

Protein level used designations for anti-Profilin 2 (PFN2) Antibodies

profilin II , profilin 2 , profilin-2 , CL2096_2 , CL2096_2_ov , CL2096_2a , GRMZM2G109842 , zmPRO2

380475 Xenopus laevis
460989 Pan troglodytes
548852 Xenopus (Silurana) tropicalis
100173558 Pongo abelii
5217 Homo sapiens
18645 Mus musculus
81531 Rattus norvegicus
771904 Gallus gallus
539034 Bos taurus
829056 Arabidopsis thaliana
542410 Zea mays
100621523 Sus scrofa
180808 Caenorhabditis elegans
Selected quality suppliers for anti-Profilin 2 (PFN2) Antibodies
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