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anti-Prostaglandin E Synthase (PTGES) Antibodies

The protein encoded by PTGES is a glutathione-dependent prostaglandin E synthase. Additionally we are shipping Prostaglandin E Synthase Kits (24) and Prostaglandin E Synthase Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTGES 9536 O14684
PTGES 64292 Q9JM51
PTGES 59103  
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Top anti-Prostaglandin E Synthase Antibodies at

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [NBP1-87852] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts. Western Blot: Prostaglandin E Synthase Antibody [NBP1-87852] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4 0.1 mL Log in to see 8 to 11 Days
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC (p) Testis Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [ABIN2581217] - Analysis of anti-PGES / PTGES antibody with human testis at concentration 10 ug/ml. 0.05 mg Log in to see 5 to 7 Days
Human Rabbit Un-conjugated IHC (p) Anti-PTGES antibody  ABIN1049251 IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 7 to 9 Days
Chicken Rabbit Un-conjugated IHC 0.05 mg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IF (p), IHC (p) Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded human bladder carcinoma labeled with Rabbit Anti PTGEs Polyclonal Antibody, Unconjugated (ABIN735788) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
Chicken Rabbit Un-conjugated IHC (p) Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [ABIN43477838] - Analysis of anti-PTGES antibody with human testis at 10 ug/ml. 0.05 mg Log in to see 8 to 11 Days
Chicken Rabbit Un-conjugated IHC (p) Human Testis (formalin-fixed, paraffin-embedded) stained with PTGES antibody ABIN213597 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 11 to 13 Days
Human Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 9 to 11 Days

PTGES Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Mouse (Murine) , ,

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Rat (Rattus) , ,

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Top referenced anti-Prostaglandin E Synthase Antibodies

  1. Human Polyclonal Prostaglandin E Synthase Primary Antibody for IHC, IHC (p) - ABIN4347784 : Camacho, Dilmé, Solà-Villà, Rodríguez, Bellmunt, Siguero, Alcolea, Romero, Escudero, Martínez-González, Vila: Microvascular COX-2/mPGES-1/EP-4 axis in human abdominal aortic aneurysm. in Journal of lipid research 2013 (PubMed)
    Show all 4 references for ABIN4347784

More Antibodies against Prostaglandin E Synthase Interaction Partners

Human Prostaglandin E Synthase (PTGES) interaction partners

  1. The identified amino acid residues can act as target sites for the design and development of drug candidates against mPGES-1

  2. These findings support the value of a prognostic and predictive role for mPGES1.

  3. Data show that statins limit hepatic myofibroblasts proliferation via a cyclooxyegnase-2 (COX-2 (show COX2 Antibodies)) and microsomal PGE (show LIPF Antibodies) synthase-1 (mPGES-1) dependent pathway.

  4. Data show that cyclooxygenase2 (COX2 (show COX2 Antibodies))overexpression induces prostaglandin E synthase (PTGES) through early growth response 1 (EGR1 (show EGR1 Antibodies)) in colorectal cancer cell lines.

  5. mPGES-1 is downregulated via EGR1 (show EGR1 Antibodies) and has a role in caffeine inhibition on PGE2 synthesis of HBx hepatocytes

  6. results demonstrate that mPGES-1 is a target gene of defective mismatch repair in human colorectal cancer, with functional consequence

  7. Altered expression of EP2 (show SPAG11B Antibodies) in patients with aspirin-exacerbated respiratory disease contributes to deficient induction of IL-1RI, reducing the capacity of IL-1beta (show IL1B Antibodies) to increase COX-2 (show COX2 Antibodies) and mPGES-1 expression, which results in low PGE2 production

  8. High levels of intra tumoral mPGES-1 is associated with poor prognosis. mPGES-1 after chemotherapy is associated with improved outcomes.

  9. mPGES-1 in prostate cancer controls stemness and amplifies epidermal growth factor receptor (show EGFR Antibodies)-driven oncogenicity

  10. we investigated the changes in promoter methylation patterns using methylation arrays and observed that the promoters of immunomodulatory factors, COX2 (show COX2 Antibodies) and PTGES, and migration-related factors, CXCR2 (show CXCR2 Antibodies) and CXCR4 (show CXCR4 Antibodies), were hypomethylated after 5-aza treatment

Mouse (Murine) Prostaglandin E Synthase (PTGES) interaction partners

  1. The results show that mPges-1 may be a direct downstream target gene of the P4 receptor (show PGR Antibodies).

  2. mPges-1 depletion modestly increased thrombogenesis in LDL-receptor (show LDLR Antibodies) knockout mice. This response was markedly further augmented by coincident deletion of the I prostanoid receptor.

  3. Data (including data from studies in knockout mice) suggest interactions of cholinergic/prostaglandin systems participate in neuroimmunomodulation; microsomal Ptges-1 is part of cholinergic anti-inflammatory response in chronic inflammatory diseases.

  4. Prostacyclin synthase (show PTGIS Antibodies) and prostaglandin E synthase-1 cooperatively exacerbate inflammatory reactions but have opposing effects on carcinogenesis.

  5. Gas6 (show GAS6 Antibodies), through upregulation of Ptges/PGE2, contributes to cancer-induced venous thrombosis.

  6. Vascular mPGES-1 plays a protective role in blood vessels and attenuates rupture of cerebral aneurysms.

  7. Suggest pivotal role of COX-2 (show COX2 Antibodies)-mPGES-1-PGE2 axis in vascular calcification. Inhibition of COX-2 (show COX2 Antibodies) or mPGES-1 may increase the risk of calcification and subsequent adverse cardiovascular events during chronic renal failure.

  8. The present results suggest that mPGES-1 plays a significant role in lymphangiogenesis during inflammation, and represents a novel target for controlling IL.

  9. data suggests that an as yet unidentified prostaglanind E synthase but not mPGES-1 may couple with COX-2 (show COX2 Antibodies) to mediate increased renal PGE2 sythsesis in DN.

  10. This study shown that mPGES-1 is expressed in the mouse brain, both in vascular endothelial cells, in several other cellular of capillary associated pericytes, astrocytes, and cells in circumventricular organs, choroid plexus, and leptomeninges.

Cow (Bovine) Prostaglandin E Synthase (PTGES) interaction partners

  1. Prostaglandin E synthase interacts with inducible heat shock protein 70 (show HSPA1A Antibodies) after heat stress in bovine primary dermal fibroblast cells.

  2. Messenger RNA and protein levels of prostaglandin (PG) E synthase (PGES), PGF2alpha receptor (PGFR), tumor necrosis factor-alpha (TNF (show TNF Antibodies)) and Fas (show FAS Antibodies) were found to be higher in the corpus luteum of pregnancy than in corpus luteum of the cycle.

  3. Data suggest that elevated temperatures stimulate PGE2 production in ampullary oviduct by increasing expression of PGES and HSP90AA1 (show HSP90AA1 Antibodies) (heat shock 90 kD protein 1 alpha).

  4. PGES pathway is responsible for the endometrial production of PGE (show LIPF Antibodies)(2) in the bovine endometrium during the estrous cycle

Horse (Equine) Prostaglandin E Synthase (PTGES) interaction partners

  1. This study showed that COX-1 (show PTGS1 Antibodies) and COX-2 (show PTGS2 Antibodies) in genital carcinomas in the horse is poor; microsomal PGES-1 is more prominently expressed.

Prostaglandin E Synthase (PTGES) Antigen Profile

Protein Summary

The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.

Gene names and symbols associated with PTGES

  • prostaglandin E synthase (PTGES) antibody
  • prostaglandin E synthase (ptges) antibody
  • prostaglandin E synthase (Ptges) antibody
  • 2410099E23Rik antibody
  • D2Ertd369e antibody
  • MGC80290 antibody
  • MGST-IV antibody
  • MGST1-L1 antibody
  • MGST1L1 antibody
  • mPGES antibody
  • MPGES-1 antibody
  • Pges antibody
  • PIG12 antibody
  • PP102 antibody
  • PP1294 antibody
  • PTGES antibody
  • TP53I12 antibody

Protein level used designations for PTGES

microsomal prostaglandin E synthase-1 , prostaglandin E synthase , MGST1-like 1 , glutathione S-transferase 1-like 1 , microsomal glutathione S-transferase 1-like 1 , microsomal prostaglandin E synthase 1 , p53-induced apoptosis protein 12 , p53-induced gene 12 protein , tumor protein p53 inducible protein 12

417193 Gallus gallus
654407 Sus scrofa
446534 Xenopus laevis
473071 Pan troglodytes
9536 Homo sapiens
64292 Mus musculus
59103 Rattus norvegicus
100733230 Cavia porcellus
282019 Bos taurus
480698 Canis lupus familiaris
100034143 Equus caballus
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