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Protein Kinase N1 Proteins (PKN1)

The protein encoded by PKN1 belongs to the protein kinase C superfamily. Additionally we are shipping PKN1 Antibodies (38) and PKN1 Kits (27) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PKN1 84432 P58294
PKN1 320795 P70268
Rat PKN1 PKN1 29355 Q63433
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Top PKN1 Proteins at

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 16 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

PKN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

More Proteins for Protein Kinase N1 (PKN1) Interaction Partners

Fruit Fly (Drosophila melanogaster) Protein Kinase N1 (PKN1) interaction partners

  1. The delorean phenotype, with its associated defects in wing morphology, provides evidence of a role for PKN in adult morphogenetic processes.

  2. Drosophila protein kinase N is a negative regulator of actin-myosin activity during oogenesis.

  3. identified a requirement for Pkn in wing morphogenesis, thereby revealing the first postembryonic function for Pkn

Human Protein Kinase N1 (PKN1) interaction partners

  1. Each follicular fluid (FF) was individually aspirated and FF/serum EG-VEGF (show Prok1 Proteins), inhibin-a (show INHA Proteins), and FF IGF-1 (show IGF1 Proteins) levels were evaluated. The pregnant group was characterized by increased numbers of WVFs (p = 0.044), a WVE (p = 0.022), and increased levels of FF IGF-1 (show IGF1 Proteins) (p = 0.001) and serum EG-VEGF (show Prok1 Proteins) (p = 0.03).

  2. Results show the biological effects of PROK1 (show Prok1 Proteins)-V67I on cell functions are similar to those of wild type, and the common variant of V67I may act as a modifier in the PROK1 (show Prok1 Proteins)-PROKR system through down-regulation of PROK1 (show Prok1 Proteins) expression.

  3. Data suggest that prokineticins (PROK1 (show Prok1 Proteins) and PROK2 (show PROK2 Proteins)) and prokineticin receptors (PROKR1 (show PROKR1 Proteins) and PROKR2 (show PROKR2 Proteins)) act as main regulators of physiological functions of ovary, uterus, placenta, and testis. [REVIEW]

  4. EG-VEGF (show Prok1 Proteins) and its receptor PKR1 (show PROKR1 Proteins) might play a role in the pathogenesis of adrenocortical tumors and could serve as prognostic markers for this rare malignant disease.

  5. The prognosis was poorer in colorectal cancers that expressed both PROK1 and VEGF relative to the cases that expressed only 1 protein, and the expression of both proteins was found to be an independent prognostic factor.

  6. TXA2-mediated neoplastic responses in prostate adenocarcinoma PC-3 (show PCSK1 Proteins) cells occur through a PRK1/PRK2 (show PKN2 Proteins)-dependent mechanism.

  7. PROK1 (show Prok1 Proteins) levels in follicular fluid and fertilization culture media could constitute new predictive noninvasive markers of successful embryo implantation in conventional in vitro fertilization-embryo transfer

  8. Simultaneous targeting of both angiogenic growth factors (VEGF (show VEGFA Proteins)/PROK1 (show Prok1 Proteins)) may prove more useful in colorectal cancer

  9. High Prokineticin 1 (show Prok1 Proteins) protein expression is associated with sporadic colorectal cancer.

  10. Expression of PROK1 (show Prok1 Proteins) and PROKR1 (show PROKR1 Proteins) was significantly higher in mid-gestation ovaries (17-20 wk) than at earlier gestations (8-11 and 14-16 wk).

Mouse (Murine) Protein Kinase N1 (PKN1) interaction partners

  1. Protein kinase N1, a cell inhibitor of Akt (show AKT1 Proteins) kinase, has a central role in quality control of germinal center formation

  2. PKN is activated by ischemia/reperfusion and inhibits apoptosis of cardiac myocytes, thereby protecting the heart from I/R injury.

  3. Leishmania mexicana infectivity is associated with differential expression of protein kinase C-like triggered during a cell-cell contact

  4. Pkn1 is involved in ganglioside signals that regulate TNF-alpha (show TNF Proteins) signaling and synthesis.

PKN1 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene names and symbols associated with Protein Kinase N1 Proteins (PKN1)

  • Protein kinase related to protein kinase N (Pkn)
  • protein kinase N1 (PKN1)
  • zgc:162290 (zgc:162290)
  • protein kinase N1 (pkn1)
  • prokineticin 1 (PROK1)
  • protein kinase N1 (Pkn1)
  • 3-2 protein
  • CG2049 protein
  • CG2055 protein
  • CT6637 protein
  • CT6660 protein
  • DBK protein
  • Dmel\\CG2049 protein
  • dPKN protein
  • EGVEGF protein
  • F730027O18Rik protein
  • l(2)06736 protein
  • l(2)45Ca protein
  • PAK-1 protein
  • PAK1 protein
  • PK1 protein
  • Pk45C protein
  • Pk?3 protein
  • Pkn protein
  • PKN-ALPHA protein
  • PKN1 protein
  • PRK1 protein
  • PRK2 protein
  • Prkcl1 protein
  • Stk3 protein
  • v(2)rG232 protein

Protein level used designations for Protein Kinase N1 Proteins (PKN1)

CG2049-PB , CG2049-PC , CG2049-PD , CG2049-PE , CG2049-PF , CG2049-PG , CG2049-PH , CG2049-PI , CG2049-PJ , CG2049-PK , CG2049-PL , CG2049-PM , Pkn-PB , Pkn-PC , Pkn-PD , Pkn-PE , Pkn-PF , Pkn-PG , Pkn-PH , Pkn-PI , Pkn-PJ , Pkn-PK , Pkn-PL , Pkn-PM , protein kinase N , protein kinase c related , protein kinase related to protein kinase N , protein kinase-like 45C , protein kinase N1 , serine/threonine-protein kinase N1-like , EG-VEGF , black mamba toxin-related protein , endocrine-gland-derived vascular endothelial growth factor , mambakine , prokineticin-1 , protease-activated kinase 1 , protein kinase C-like 1 , protein kinase C-like PKN , protein kinase C-related kinase 1 , protein kinase PKN-alpha , protein-kinase C-related kinase 1 , serine-threonine kinase N , serine-threonine protein kinase N , serine/threonine protein kinase N , serine/threonine-protein kinase N1 , serine/threonine kinase 3 , protein kinase PKN

35950 Drosophila melanogaster
455785 Pan troglodytes
100007897 Danio rerio
100379847 Xenopus (Silurana) tropicalis
100401855 Callithrix jacchus
84432 Homo sapiens
5585 Homo sapiens
320795 Mus musculus
29355 Rattus norvegicus
100713234 Cavia porcellus
509080 Bos taurus
101118101 Ovis aries
484903 Canis lupus familiaris
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