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anti-RNA Binding Protein, Fox-1 Homolog (C. Elegans) 3 (RBFOX3) Antibodies

RNA-binding protein that regulates alternative splicing events (By similarity).. Additionally we are shipping NEUN Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RBFOX3 146713 A6NFN3
RBFOX3 52897 Q8BIF2
RBFOX3 287847  
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Top anti-NEUN Antibodies at antibodies-online.com

Showing 10 out of 55 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Frozen section rat brain labeled with Anti-NeuN Polyclonal Antibody, Unconjugated (ABIN732068) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse brain labeled with Anti-NeuN Polyclonal Antibody, Unconjugated (ABIN732068) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Mouse Un-conjugated ICC, IF, IHC, WB Rat brain neural cultures stained with ABIN1580419 (red), rabbit antibody to GFAP CPCA-GFAP (green) and DNA (blue). The ABIN1580419 antibody reveals strong nuclear and distal cytoplasmic staining for Fox3/NeuN and the complete absence of staining of astrocytes, which are staining with the GFAP antibody, and other kinds of non-neuronal cells. This Fox3/NeuN antibody is therefore an excellent marker of neuronal cells. Omim Link: Currently no OMIM entry. References: 1. Hodgkin J, Zellan JD, Albertson DG. Identification of a candidate primary sex determination locus, fox-1, on the X chromosome of Caenorhabditis elegans. Development 120:3681-3689 (1994). 2. Mullen RJ, Buck CR, Smith AM. NeuN, a neuronal specific nuclear protein in vertebrates. Development 116:201-211 (1994). 3. Herculano-Houzel S, Lent R. Isotropic fractionator: a simple, rapid method for the quantification of total cell and neuron numbers in the brain. J Neurosci. 25:2518-21 (2005). 4. Kim KK, Adelstein RS, Kawamoto S. Identification of neuronal nuclei (NeuN) as Fox-3, a new member of the Fox-1 gene family of splicing factors. J. Biol. Chem. 284:31052-31061 (2009). 5. Underwood,J.G., Boutz,P.L., Dougherty,J.D., Stoilov,P. and Black,D.L. Homologues of the Caenorhabditis elegans Fox-1 protein are neuronal splicing regulators in mammals. Mol. Cell. Biol. 25:10005-10016 (2005). Limitations: This product is for research use only and is not approved for use in humans or in clinical diagnosis. © Biotechnology Inc. June 4, 2014. 100 μL Log in to see 2 to 3 Days
$220.00
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Mouse Un-conjugated ICC, IF, WB   100 μL Log in to see 8 to 10 Days
$434.50
Details
Human Chicken Un-conjugated IF, IHC (p) CA1 region of a transgenic Mouse expressing the eGFP gene product under control of the Thy-1 promoter. Green is eGFP autofluorescence. Red is Cy-3 secondary antibody labeling Chicken anti-Neu-N (Fox-3) positive neuronal nuclei. Picture courtesy of Dr. Felix Eckenstein, University of Vermont. 0.1 mg Log in to see 6 to 8 Days
$522.50
Details
Mouse Rabbit Un-conjugated IHC, WB Immunohistochemistry of paraffin-embedded Mouse brain using NeuN antibody at dilution of 1:100 (x400 lens). Immunohistochemistry of paraffin-embedded mouse kidney using NeuN antibody at dilution of 1:200 (x400 lens). 200 μL Log in to see 9 Days
$588.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

RBFOX3 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-NEUN Antibodies

  1. Human Polyclonal NEUN Primary Antibody for IF (p), IHC (p) - ABIN732068 : Jiang, Tian, Fu, Zhu, Hou: Neuroprotective efficacy and therapeutic window of Forsythoside B: in a rat model of cerebral ischemia and reperfusion injury. in European journal of pharmacology 2010 (PubMed)
    Show all 7 references for ABIN732068

  2. Human Monoclonal NEUN Primary Antibody for ICC, IF - ABIN1580419 : Herculano-Houzel, Lent: Isotropic fractionator: a simple, rapid method for the quantification of total cell and neuron numbers in the brain. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2005 (PubMed)
    Show all 3 references for ABIN1580419

  3. Human Polyclonal NEUN Primary Antibody for IF (p) - ABIN908077 : Fontes, Ramsey, Polk, Koop, Denisova, Belousov: Death of Neurons following Injury Requires Conductive Neuronal Gap Junction Channels but Not a Specific Connexin. in PLoS ONE 2015 (PubMed)

More Antibodies against NEUN Interaction Partners

Human RNA Binding Protein, Fox-1 Homolog (C. Elegans) 3 (RBFOX3) interaction partners

  1. RBFOX proteins can facilitate the splicing of micro-exons. We also found that PTBP1 (show PTBP1 Antibodies) likely regulates the inclusion of micro-exons, possibly by repressing the inclusion of micro-exons that are enhanced by RBFOX proteins and other splicing factors.[RBFOX]

  2. RNA splicing occurs in the nucleus hence, the altered localization of RbFox3 to the cytoplasm may lead to the downregulation of neuronal gene expression.

  3. Exome sequencing of 242 rolandic epilepsy patients revealed two novel probably deleterious variants in RBFOX1 (show A2BP1 Antibodies), a frameshift mutation (p.A233Vfs*74) and a hexanucleotide deletion (p.A299_A300del), and a novel nonsense mutation in RBFOX3 (p.Y287*).

  4. High NeuN levels are associated with supratentorial ependymomas.

  5. NeuN immunocytochemical reaction in neurons of human substantia nigra was expressed much weaker than in the nucleus rubrum neurons located in the same sections.

  6. In addition, eight genes classified as 'second tier' hits in the original study (PAX7 (show PAX7 Antibodies), THADA, COL8A1 (show COL8A1 Antibodies)/FILIP1L (show FILIP1L Antibodies), DCAF4L2, GADD45G (show GADD45G Antibodies), NTN1 (show NTN1 Antibodies), RBFOX3 and FOXE1 (show FOXE1 Antibodies)) showed evidence of linkage and association in this replication sample.

  7. NeuN (neuronal nuclei) is a neuron-specific nuclear protein identified by anti-NeuN antibody, and widely used as the postmitotic neuron marker. NeuN is identified as the Fox-3 gene product by mass spectrometry, immunoblotting, RNAi, and immunostaining.

Mouse (Murine) RNA Binding Protein, Fox-1 Homolog (C. Elegans) 3 (RBFOX3) interaction partners

  1. RBFOX3/NeuN is Required for Hippocampal Circuit Balance and Function.

  2. In vitro analyses revealed that Rbfox3 functions as a positive and a negative regulator at the stage of pri-miRNA processing to precursor miRNA (pre-miRNA).

  3. Rbfox3-dependent Numb (show NUMB Antibodies) alternative splicing plays an important role in the progression of neuronal differentiation during vertebrate development.

  4. the negative regulation of Rbfox2 (show RBM9 Antibodies) by Rbfox3 through a novel mechanism

  5. During the development of olfactory bulb and epithelium, NeuN is expressed only in mature neural cells migrating from margin area to the inner granule cells layer of olfactory bulb.

  6. NeuN is the Fox-3 gene product and its expression is restricted to neural tissues.

  7. Enzymatic dephosphorylation abolishes NeuN immunoreactivity, confirming that NeuN is indeed a phosphoprotein, and establishing that binding of the defining antibody depends on its state of phosphorylation.

  8. Data show that inhibition of ZNF238 (RP58 (show ZNF238 Antibodies)) expression in mouse GNPs decreases the expression of the neuronal differentiation markers MAP2 and NeuN and downregulates the expression of the cell cycle arrest protein p27 (show CDKN1B Antibodies), a regulator of GNP differentiation.

NEUN (RBFOX3) Antigen Profile

Protein Summary

RNA-binding protein that regulates alternative splicing events (By similarity).

Gene names and symbols associated with RBFOX3

  • RNA binding protein, fox-1 homolog (C. elegans) 3 (RBFOX3) antibody
  • RNA binding protein, fox-1 homolog (C. elegans) 3 (Rbfox3) antibody
  • Fox-3 antibody
  • FOX3 antibody
  • Hrnbp3 antibody
  • Neun antibody
  • Neuna60 antibody
  • RGD1560070 antibody

Protein level used designations for RBFOX3

RNA binding protein fox-1 homolog 3 , fox-1 homolog C , hexaribonucleotide binding protein 3 , neuronal nuclei , neuronal nuclear antigen A60 , RNA binding protein, fox-1 homolog 3

GENE ID SPECIES
146713 Homo sapiens
52897 Mus musculus
511773 Bos taurus
287847 Rattus norvegicus
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