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Runt-Related Transcription Factor 3 (RUNX3) ELISA Kits

RUNX3 encodes a member of the runt domain-containing family of transcription factors. Additionally we are shipping RUNX3 Antibodies (116) and RUNX3 Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
RUNX3 12399  
RUNX3 864 Q13761
RUNX3 156726  
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More ELISA Kits for RUNX3 Interaction Partners

Zebrafish Runt-Related Transcription Factor 3 (RUNX3) interaction partners

  1. successive induction of the transcription factors Runx3, Egr1 and Sox9b constitutes a regulatory cascade that controls expression of Follistatin A in pharyngeal endoderm, the latter modulating BMP signaling in developing cranial cartilage in zebrafish

  2. Runx3 expression leads to an increase in primitive blood cell numbers, together with an increase in runx1 (show RUNX1 ELISA Kits)-expressing cells in the ventral wall of the dorsal aorta.

  3. Zebrafish embryos lacking Rad21 (show RAD21 ELISA Kits), or cohesin subunit Smc3 (show SMC3 ELISA Kits), fail to express runx3 and lose hematopoietic runx1 (show RUNX1 ELISA Kits) expression in early embryonic development.

Mouse (Murine) Runt-Related Transcription Factor 3 (RUNX3) interaction partners

  1. Runx3 is crucial for the phenotypic and functional changes observed in ThPok (show ZBTB7B ELISA Kits)-deficient invariant natural killer T cells.

  2. the transcription factor Runx3 was essential for the normal development of subsets of innate lymphoid cells (ILCs) in the mucosa

  3. Runx1 and Runx3 are the downstream effectors of Nanog, especially in the early and intermediate osteogenic differentiation of the mouse mesenchymal cell line C3H10T1/2.

  4. nonpermissive expression of RUNX3 protein is restricted at the translational level, and that the repression is further enforced by a transcriptional regulation for maintenance of diverse developmental plasticity of T cells for different effector subsets.

  5. Our findings establish Nr4a1 (show NR4A1 ELISA Kits) as a novel and critical player in the regulation of CD8 (show CD8A ELISA Kits) T cell development through the direct suppression of Runx3.

  6. Runx1 (show RUNX1 ELISA Kits) Runx3 DKO mice exhibit bone marrow failure and myeloproliferative disorder. RUNX proteins are important for FANCD2 (show FANCD2 ELISA Kits) recruitment to DNA repair foci.

  7. inflammation-mediated tumor promotion requires leukocytic Runx3 expression

  8. Bone histomorphometry revealed that decreased osteoblast numbers and reduced mineral deposition capacity in Runx3-deficient mice cause this bone formation deficiency.

  9. RUNX3 expression suppresses metastasis and angiogenesis of human prostate cancer.

  10. CD31 (show PECAM1 ELISA Kits), vascular endothelial growth factor A (show VEGFA ELISA Kits) and von Willebrand Factor (show VWF ELISA Kits) were dramatically up-regulated by a loss of Runx3 during lung development.

Human Runt-Related Transcription Factor 3 (RUNX3) interaction partners

  1. the AA genotype and A allele of rs2236852 polymorphism confer a decreased CRC (show CALR ELISA Kits) risk, while the TA haplotype (rs760805 and rs2236852) increases the risk for CRC (show CALR ELISA Kits) development in Mexican patients.

  2. HMGB1 (show HMGB1 ELISA Kits) contributed to IFN-gamma (show IFNG ELISA Kits)-producing Th17-cell bias in coronary artery atherosclerosis by controlling expression of T-bet and RUNX3.

  3. Targeting miR (show MLXIP ELISA Kits)-130a and miR (show MLXIP ELISA Kits)-495 could be a potential therapeutics to recover RUNX3 expression under hypoxic conditions and in early tumorigenic progression.

  4. RUNX 3 promoter hypermethylation can lead to down-regulation of RUNX3 in laryngeal squamous cell carcinoma.

  5. aberrant expression of RUNX3 was associated with the pathogenesis of Immune thrombocytopenia and therapeutically targeting it might be a novel approach in Immune thrombocytopenia treatment

  6. miR (show MLXIP ELISA Kits)-130a was identified as an oncogene (show RAB1A ELISA Kits) that promotes gastric cancer tumorigenesis by targeting RUNX3.

  7. we show that RUNX3 and RUNX3-regulated chemokines are linked to non-small cell lung cancer-mediated bone resorption

  8. Data show that the Lim domain only 2 (LMO2 (show LMO2 ELISA Kits)) regulatory element (element-25) region consists of transcription factor GATA2 (show GATA2 ELISA Kits)-binding myeloid ennhancer and RUNX protein-binding T-cell repressor.

  9. Exogenous expression of RUNX3 resulted in the enhancement of Ara (show FOXC1 ELISA Kits)-C resistance in K562 cells. RUNX3 is a downstream target of FLT3 (show FLT3 ELISA Kits)-ITD. RUNX3 is a prerequisite for Ara (show FOXC1 ELISA Kits)-C resistance via FLT3 (show FLT3 ELISA Kits)-ITD signaling.

  10. RUNX3 hypermethylation is associated with an increased risk and worse survival in non-small cell lung cancer

RUNX3 Antigen Profile

Antigen Summary

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RUNX3

  • runt-related transcription factor 3 (runx3) antibody
  • runt-related transcription factor 3 (RUNX3) antibody
  • frRunx3/p45 (frrunx3) antibody
  • runt related transcription factor 3 (Runx3) antibody
  • runt-related transcription factor 3 (Runx3) antibody
  • AML2 antibody
  • Cbfa3 antibody
  • frrunx3 antibody
  • Pebp2a3 antibody
  • PEBP2aC antibody
  • runx3 antibody
  • runxb antibody

Protein level used designations for RUNX3

runt-related transcription factor b , runt-related transcription factor 3 , core-binding factor 3 , frRunx3/p45 , CBF-alpha-3 , PEA2-alpha C , PEBP2-alpha C , SL3-3 enhancer factor 1 alpha C subunit , SL3/AKV core-binding factor alpha C subunit , acute myeloid leukemia 2 protein , core binding factor alpha 3 , core-binding factor subunit alpha-3 , oncogene AML-2 , polyomavirus enhancer-binding protein 2 alpha C subunit , runt domain, alpha subunit 3 , transcription factor AML2/CBFA3 , PEA2 alpha C , PEBP2 alpha C , acute myeloid leukemia gene 2 , core-binding factor, runt domain, alpha subunit 3 , transcription factor AML2 , Runt related transcription factor 3 , Runx3 MASN-variant

58127 Danio rerio
403159 Sus scrofa
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100049632 Takifugu rubripes
100474431 Ailuropoda melanoleuca
100500732 Xenopus laevis
12399 Mus musculus
864 Homo sapiens
617389 Bos taurus
156726 Rattus norvegicus
769687 Gallus gallus
487366 Canis lupus familiaris
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