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RUNX3 Products

(Runt-Related Transcription Factor 3 (RUNX3))

Categories

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured RUNX3 Categories

RUNX3 Antibodies

High quality antibodies with extensive validation data.

RUNX3 ELISA Kits

Reliable ELISA kits for a wide range of species.

RUNX3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RUNX3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, FACS, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (1)
  • (1)
Cat. No. ABIN1714069
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB
Validations
  • (6)
Cat. No. ABIN571630
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS, ICC, IHC, WB
Validations
  • (7)
Cat. No. ABIN5611280
Quantity 0.1 mg
Datasheet Datasheet

Recommended RUNX3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959208
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validations
Cat. No. ABIN5648562
Quantity 96 tests
Datasheet Datasheet

Recommended RUNX3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3087595
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3123245
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319002
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our RUNX3 products

Li, Zhao, Huang, Wang, Zhu, Cao, Xiong, Deng: "MiR-93-5p promotes gastric cancer-cell progression via inactivation of the Hippo signaling pathway." in: Gene, Vol. 641, pp. 240-247, (2017) (PubMed).

Zhu, Xu, Hu, Feng, Jiang, Hou, Cao, Han, Ling, Ge: "Pim-1 acts as an oncogene in human salivary gland adenoid cystic carcinoma." in: Journal of experimental & clinical cancer research : CR, Vol. 33, Issue 1, pp. 114, (2015) (PubMed).

Shi, Wang, Liu, Chen: "Inactivation of RUNX3 predicts poor prognosis in esophageal squamous cell carcinoma after Ivor-Lewis esophagectomy." in: Medical oncology (Northwood, London, England), Vol. 31, Issue 12, pp. 309, (2014) (PubMed).

Yoshikawa, Murakami, Senzaki, Masuda, Ozaki, Ito, Shiga: "Coexpression of Runx1 and Runx3 in mechanoreceptive dorsal root ganglion neurons." in: Developmental neurobiology, Vol. 73, Issue 6, pp. 469-79, (2013) (PubMed).

Chuang, Ito, Ito: "RUNX family: Regulation and diversification of roles through interacting proteins." in: International journal of cancer. Journal international du cancer, Vol. 132, Issue 6, pp. 1260-71, (2013) (PubMed).

Lotem, Levanon, Negreanu, Leshkowitz, Friedlander, Groner: "Runx3-mediated transcriptional program in cytotoxic lymphocytes." in: PLoS ONE, Vol. 8, Issue 11, pp. e80467, (2013) (PubMed).

Reis, Rogoz, Costa-Pinto, Taniuchi, Mucida: "Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4⁺ T cell immunity." in: Nature immunology, Vol. 14, Issue 3, pp. 271-80, (2013) (PubMed).

Chopin, Seillet, Chevrier, Wu, Wang, Morse, Belz, Nutt: "Langerhans cells are generated by two distinct PU.1-dependent transcriptional networks." in: The Journal of experimental medicine, Vol. 210, Issue 13, pp. 2967-80, (2013) (PubMed).

Zou, Li, Klein, Xiang: "Brn3a/Pou4f1 regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord." in: Developmental biology, Vol. 364, Issue 2, pp. 114-27, (2012) (PubMed).

Presnell, Zhang, Chlebowy, Al-Attar, Lutz: "Differential transcription factor use by the KIR2DL4 promoter under constitutive and IL-2/15-treated conditions." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 9, pp. 4394-404, (2012) (PubMed).

Synonyms and alternative names related to RUNX3

runt-related transcription factor 3 (runx3), runt-related transcription factor 3 (RUNX3), runt related transcription factor 3 (RUNX3), runt related transcription factor 3 (runx3), runt related transcription factor 3 L homeolog (runx3.L), runt related transcription factor 3 (Runx3), runt-related transcription factor 3 (Runx3), aml2, AML2, CBFA3, cbfa3, Cbfa3, frrunx3, Pebp2a3, pebp2ac, PEBP2aC, RUNX3, runx3, runxb

Protein level used designations for RUNX3

  • runt-related transcription factor b
  • runt-related transcription factor 3
  • core-binding factor 3
  • frRunx3/p45
  • CBF-alpha-3
  • PEA2-alpha C
  • PEBP2-alpha C
  • SL3-3 enhancer factor 1 alpha C subunit
  • SL3/AKV core-binding factor alpha C subunit
  • acute myeloid leukemia 2 protein
  • core binding factor alpha 3
  • core-binding factor subunit alpha-3
  • oncogene AML-2
  • polyomavirus enhancer-binding protein 2 alpha C subunit
  • runt domain, alpha subunit 3
  • transcription factor AML2/CBFA3
  • PEA2 alpha C
  • PEBP2 alpha C
  • acute myeloid leukemia gene 2
  • core-binding factor, runt domain, alpha subunit 3
  • transcription factor AML2
  • Runt related transcription factor 3
  • Runx3 MASN-variant
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