Sal-Like 2 (Drosophila) Proteins (SALL2)

Probable transcription factor.. Additionally we are shipping SALL2 Antibodies (28) and SALL2 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat SALL2 SALL2 305854  
SALL2 6297 Q9Y467
SALL2 50524 Q9QX96
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Top SALL2 Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days

SALL2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine)

More Proteins for Sal-Like 2 (Drosophila) (SALL2) Interaction Partners

Human Sal-Like 2 (Drosophila) (SALL2) interaction partners

  1. Understanding SALL2 function and the molecular mechanisms governing its expression and activity is critical to comprehend why and how SALL2 could contribute to disease. This knowledge will open new perspectives for the development of molecular targeted approaches in disease

  2. Sall2 enhanced the p16 minigene blocking of cell cycle progression and p16 knockdown with siRNA abolished most of the Sall2 inhibition of cell cycle progression

  3. Mechanisms of silencing SALL2 in OVCA cell lines and primary tumors and possible therapeutic approaches for ovarian carcinoma are discussed in this review.

  4. A role for SALL2 in eye morphogenesis and loss of function of the gene causes ocular coloboma in humans and mice.

  5. The SALL2 P2 promoter is hypermethylated in a majority of serous ovarian carcinomas.

  6. c-MYC may come under negative regulation by p150, consistent with the action of p150 as a putative tumor suppressor.

  7. Here, the authors report that human papillomavirus type 16 E6 targets the cellular factor p150(Sal2), which positively regulates p21(WAF1 (show CDKN1A Proteins)) transcription.

  8. Results demonstrate binding of p150(Sal2) to two natural promoters with GC elements related to the optimal binding sequence defined in vitro and whose regulation is important for suppression of tumor growth.

  9. A CUL4/DDB1 E3 ligase containing RBBP7 (show RBBP7 Proteins) as the p150(Sal2) receptor has been identified as mediating the destruction of p150(Sal2) as cells transition from a quiescent to an actively growing state.

  10. Studies indicate that vertebrate sal orthologues (spalt-like/sall) have important developmental roles during neural development and organogenesis and gentic diseases.

Mouse (Murine) Sal-Like 2 (Drosophila) (SALL2) interaction partners

  1. In addition, studies in leukemia Jurkat T cells support the existence of the Sall2/Noxa (show PMAIP1 Proteins) axis, and the significance of this axis on the apoptotic response to doxorubicin in cancer cells.

  2. Data show that p53 (show TP53 Proteins) activation diminished SALL2 RNA and protein levels during genotoxic cellular stress in primary embryo fibroblasts (MEFs).

  3. We have now generated mice lacking Sall2.Mice lacking both Sall1 and Sall2 show kidney phenotypes comparable to those of Sall1 knockout, thereby demonstrating the dispensable roles of Sall2 in embryonic and kidney development

  4. Results suggest that p150(Sal2), acting in part as a p53 (show TP53 Proteins)-independent regulator of p21 and BAX (show BAX Proteins), can function in some cell types as a regulator of cell growth and survival.

  5. These data establish Sall2 as a link between p75 neurotrophin receptor (show NGFR Proteins) and transcriptional events that regulate the growth and development of neuronal cells.

SALL2 Protein Profile

Protein Summary

Probable transcription factor.

Gene names and symbols associated with SALL2

  • spalt-like transcription factor 2 (Sall2)
  • spalt like transcription factor 2 (SALL2)
  • sal-like 2 (Drosophila) (Sall2)
  • AI225809 protein
  • AW559097 protein
  • HSAL2 protein
  • mKIAA0360 protein
  • Msal-2 protein
  • p150(Sal2) protein
  • Sal-2 protein
  • ZNF795 protein

Protein level used designations for SALL2

sal-like protein 2 , zinc finger protein 795 , zinc finger protein SALL2 , zinc finger protein Spalt-2 , spalt-like protein 2

305854 Rattus norvegicus
6297 Homo sapiens
50524 Mus musculus
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