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Secretogranin III Proteins (SCG3)

The protein encoded by SCG3 is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Additionally we are shipping Secretogranin III Antibodies (63) and Secretogranin III Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SCG3 29106 Q8WXD2
SCG3 20255 P47867
SCG3 116635 P47868
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Top Secretogranin III Proteins at

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
HOST_Human Human His tag   10 μg Log in to see 5 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days

SCG3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,

Mouse (Murine)

Rat (Rattus)

Top referenced Secretogranin III Proteins

  1. Human SCG3 Protein expressed in Human Cells - ABIN2006675 : Rong, Liu, Zeng, Ma, Wei, Han: Cloning and characterization of a novel human secretory protein: secretogranin III. in Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 2002 (PubMed)

More Proteins for Secretogranin III (SCG3) Interaction Partners

Human Secretogranin III (SCG3) interaction partners

  1. HBXIP (show HBXIP Proteins) facilitates the proliferation of hepatoma cells by up-regulating SCG3 via E2F1 (show E2F1 Proteins) and miR (show MLXIP Proteins)-509-3p modulation.

  2. SCG3 is essential in the process and targeting of neuropeptides and neurotrophins, its participation in the pathological progression of Alzheimer's disease may be suggested

  3. SCG3 may be involved in apoptosis signal transduction as a caspase (show CASP3 Proteins) substrate.It may be a pivotal component of the neuroendocrine pathway & play an important role in neuronal communication & neurotransmitter release.

  4. Our data suggest that genetic variations in the FTO (show FTO Proteins), SCG3 and MTMR9 (show MTMR9 Proteins) genes independently influence the risk of metabolic syndrome.

  5. This short review deals with investigations in neuroendocrine tumors (NETs) with antibodies against defined epitopes of chromogranins (Cgs) A and B and secretogranins (Sgs (show FBN1 Proteins)) II and III.

  6. SgIII was expressed in 41 of 47 neuroendocrine tumours. The expression of SgIII agreed well with that of CgA (show CGA Proteins), CgB (show CGB Proteins) and SgII (show SEMG2 Proteins), with exceptions of phaeochromocytomas and parathyroid adenomas.

  7. Genetic variations in the SCG3 gene may influence the risk of obesity through possible regulation of hypothalamic neuropeptide secretion.

  8. these data suggest that SgIII, DMT-1 (show DMRT1 Proteins) and HNP-1 (show DEFA1 Proteins) are implicated in cell-mediated LDL oxidation.

Mouse (Murine) Secretogranin III (SCG3) interaction partners

  1. SgIII knockdown impairs intracellular retention of chromogranin A (show CHGA Proteins) and proopiomelanocortin (show POMC Proteins) in AtT-20 cells.

  2. The robust expression of SgIII in astrocytes and its regulation in the injured brain suggest both intracellular and extracellular roles for this glial granin in the physiology and repair/damage of neuronal circuits.

  3. SgIII directly binds to cholesterol components of the secretory granule membrane and targets chromogranin A (show CHGA Proteins) to secretory granules in pituitary and pancreatic endocrine cells

  4. SgIII and CPE (show CPE Proteins) form the separate functional sorting complex by anchoring to cholesterol-rich SG membranes, and POMC (show POMC Proteins)-derived peptides are transferred from CPE (show CPE Proteins) to SgIII, and subsequently to CgA (show CGA Proteins).

  5. SCG2 (show SCG2 Proteins), as well as SCG3, may be a potential regulator of food intake based on its capacity to accumulate appetite-related hormones into secretory granules.

Secretogranin III (SCG3) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones\; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Secretogranin III Proteins (SCG3)

  • secretogranin III (scg3)
  • secretogranin III (SCG3)
  • secretogranin III (Scg3)
  • 1B1075 protein
  • AI385542 protein
  • Chgd protein
  • DKFZp459J1919 protein
  • scg3-A protein
  • SGIII protein
  • zgc:73236 protein

Protein level used designations for Secretogranin III Proteins (SCG3)

secretogranin III , secretogranin-3 , secretogranin-3-like , 1B1075

373575 Xenopus laevis
393730 Danio rerio
415424 Gallus gallus
453437 Pan troglodytes
478307 Canis lupus familiaris
694089 Macaca mulatta
100055140 Equus caballus
100125084 Xenopus (Silurana) tropicalis
100154760 Sus scrofa
100173578 Pongo abelii
100343331 Oryctolagus cuniculus
100412626 Callithrix jacchus
100465413 Ailuropoda melanoleuca
29106 Homo sapiens
20255 Mus musculus
116635 Rattus norvegicus
525941 Bos taurus
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