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Sirtuin 3 (SIRT3) ELISA Kits

SIRT3 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Additionally we are shipping SIRT3 Antibodies (236) and SIRT3 Proteins (15) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SIRT3 23410 Q9NTG7
SIRT3 64384 Q8R104
SIRT3 293615  
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Top SIRT3 ELISA Kits at

Showing 3 out of 18 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.112 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
Rat 0.053 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
Mouse 0.054 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days

More ELISA Kits for SIRT3 Interaction Partners

Human Sirtuin 3 (SIRT3) interaction partners

  1. This study underscores an essential role of SIRT3 in the antitumor effect of Bcl-2 (show BCL2 ELISA Kits) inhibitors in human ovarian cancer through regulating both metabolism and apoptosis. The manipulation of Bcl-2 (show BCL2 ELISA Kits) inhibitors combined with the use of classic glycolysis inhibitors may be rational strategies to improve ovarian cancer therapy.

  2. Results elucidated the function of SIRT3 in hepatocellular carcinoma development and suggested that SIRT3 might function as tumor suppressor in hepatocellular carcinoma by targeting PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) pathway.

  3. Dissection of subnetwork architecture led to identification of a fundamental role for SIRT3 in homeostasis of mitochondrial membrane potential. In total, 89 interacting proteins were identified, and extensive validation points to the robustness of the derived network.

  4. SIRT3 overexpression dramatically increased cell viability in a cell model of Parkinson's disease.

  5. Insufficient expression of Sirt3 leads to inefficient mitochondrial biogenesis with decreased developmental competence of human in vitro matured oocytes.

  6. SIRT3 overexpression disrupts mitochondrial proteostasis that causes overproduction of reactive oxygen species and the cell cycle arrest to suppress cell proliferation.

  7. Data indicate that compared to non-neoplastic endometria (NNE (show ENO1 ELISA Kits)), endometrial cancer (EC) showed SIRT7 (show SIRT7 ELISA Kits) mRNA overexpression, whereas SIRT1 (show SIRT1 ELISA Kits), SIRT2 (show SIRT2 ELISA Kits), SIRT4 (show SIRT4 ELISA Kits) and SIRT5 (show SIRT5 ELISA Kits) were underexpressed, and no significant differences were observed for SIRT3 and SIRT6 (show SIRT6 ELISA Kits).

  8. microseed matrix seeding (MMS) was used to obtain crystals of human Sirt3 in its apo form and of human Sirt2 in complex with ADP ribose (ADPR).

  9. The results suggest that NRF-2 (show GABPA ELISA Kits) is a regulator of SIRT3 expression and may shed light on how SIRT3 is upregulated during nutrient stress.

  10. Data suggest that DNA sequence variants (DSVs) identified in myocardial infarction (MI) patients may change sirtuin 3 (SIRT3) level by affecting the transcriptional activity of SIRT3 gene promoter, contributing to the MI development as a risk factor.

Mouse (Murine) Sirtuin 3 (SIRT3) interaction partners

  1. Data show that peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1alpha (show PPARGC1A ELISA Kits)) overexpression significantly increased the expression of sirtuin 3 (SIRT3) and sirtuin 5 (SIRT5 (show SIRT5 ELISA Kits)).

  2. These results suggest that the antiinflammatory phenotype of FABP4/aP2 null mice is mediated by increased intracellular monounsaturated fatty acids leading to the increased expression of both uncoupling protein 2 (show UCP2 ELISA Kits) and SirT3.

  3. despite pre-existing defects in cardiac function and mitochondrial respiratory capacity in SIRT3(-/-) mice, SIRT3 deficiency does not additionally impair cardiac function following myocardial ischemia-reperfusion injury or following myocardial infarction

  4. In the cochlea, the expression of SIRT1 (show SIRT1 ELISA Kits), 3, and 5 (both mRNA and protein) was decreased in the old mice

  5. SIRT3 plays pivotal roles in adaptive responses of neurons to physiological challenges and resistance to degeneration.

  6. Results point to an antioxidant defense mechanism presented by Sirt3 through the activation of Foxo3a (show FOXO3 ELISA Kits), in microglia

  7. Sirt3 activation protects the heart from doxorubicin-induced cardiotoxicity by maintaining OGG1 (show OGG1 ELISA Kits) levels and protecting mitochondria from DNA damage.

  8. CerS1 (show CERS1 ELISA Kits), -2, and -6 are hyperacetylated in the mitochondria of SIRT3-null mice.

  9. as compared to Sirt3 overexpressed and normal groups, the acetylation of IDH2 (show IDH2 ELISA Kits) and accumulation of ox-LDL were significantly higher in the Sirt3 inhibited group

  10. Sirt3-dependent deacetylation of SOD2 (show SOD2 ELISA Kits) plays a protective role against oxidative stress and meiotic defects in oocytes under maternal obese conditions.

Cow (Bovine) Sirtuin 3 (SIRT3) interaction partners

  1. The results indicate that the variations in the class I sirtuin (show SIRT1 ELISA Kits) genes and their corresponding genotypes may be considered as molecular markers for economic traits in cattle breeding.

  2. The expression profile of sirtuin 1 (show SIRT1 ELISA Kits) and sirtuin 3 in the liver, muscle, and adipose tissue of calves and bulls is reported.

SIRT3 Antigen Profile

Antigen Summary

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

Gene names and symbols associated with Sirtuin 3 (SIRT3) ELISA Kits

  • sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae) (sirt3) antibody
  • sirtuin 3 (SIRT3) antibody
  • sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae) (SIRT3) antibody
  • sirtuin 3 (Sirt3) antibody
  • 2310003L23Rik antibody
  • AI848213 antibody
  • Sir2l3 antibody
  • sirtuin antibody
  • zgc:158774 antibody

Protein level used designations for Sirtuin 3 (SIRT3) ELISA Kits

sirtuin 3 , sirtuin , NAD-dependent deacetylase sirtuin-3, mitochondrial , NAD-dependent protein deacetylase sirtuin-3, mitochondrial , SIR2-like protein 3 , mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase , regulatory protein SIR2 homolog 3 , silent mating type information regulation 2, S.cerevisiae, homolog 3 , sir2-like 3 , sirtuin type 3 , SIRT3 mitochondrial , NAD-dependent deacetylase sirtuin-3 , NAD-dependent protein deacetylase sirtuin-3 , SIRT3L mitochondrial , mSIR2L3 , mitochondrial protein lysine deacetylase , silent mating type information regulation 2, (S.cerevisiae, homolog)-like 3

558775 Danio rerio
100604320 Nomascus leucogenys
422988 Gallus gallus
23410 Homo sapiens
475933 Canis lupus familiaris
100354500 Oryctolagus cuniculus
64384 Mus musculus
293615 Rattus norvegicus
101087609 Felis catus
614027 Bos taurus
100125971 Sus scrofa
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