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SIRT3 Products

(Sirtuin 3 (SIRT3))

Categories

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008].

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Featured SIRT3 Categories

SIRT3 Antibodies

High quality antibodies with extensive validation data.

SIRT3 ELISA Kits

Reliable ELISA kits for a wide range of species.

SIRT3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SIRT3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application IHC, ELISA, WB
Validations
  • (6)
Cat. No. ABIN3032590
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS, ICC, IHC, WB
Validations
  • (5)
Cat. No. ABIN5542439
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application IHC, WB
Validations
  • (5)
Cat. No. ABIN7270324
Quantity 100 μL
Datasheet Datasheet

Recommended SIRT3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970232
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959491
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959492
Quantity 96 tests
Datasheet Datasheet

Recommended SIRT3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1320045
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320046
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3011681
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SIRT3 products

Nyárády, Turai, Funke, Györgyi, Makai, Prémusz, Bódis, Sulyok: "Effects of perinatal factors on sirtuin 3, 8-hydroxy-2'- deoxyguanosine, brain-derived neurotrophic factor and serotonin in cord blood and early breast milk: an observational study." in: International breastfeeding journal, Vol. 15, Issue 1, pp. 57, (2020) (PubMed).

Rezaei, Keshtzar, Khodayar, Javadipour: "SirT3 regulates diabetogenic effects caused by arsenic: An implication for mitochondrial complex II modification." in: Toxicology letters, Vol. 301, pp. 24-33, (2019) (PubMed).

Li, Chen, Yang, He, He, Xia, Zhang, Xiang: "Single-walled carbon nanohorn aggregates promotes mitochondrial dysfunction-induced apoptosis in hepatoblastoma cells by targeting SIRT3." in: International journal of oncology, Vol. 53, Issue 3, pp. 1129-1137, (2018) (PubMed).

Schwab, Sison, Meade, Broniowska, Corbett, Ebert: "Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons." in: Stem cell reports, Vol. 9, Issue 6, pp. 1839-1852, (2018) (PubMed).

Xu, Gao, Zhang, Wei, Chen, Dai, Zeng, Zhao: "SIRT1/3 Activation by Resveratrol Attenuates Acute Kidney Injury in a Septic Rat Model." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 7296092, (2017) (PubMed).

Vidimar, Gius, Chakravarti, Bulun, Wei, Kim: "Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas." in: Science advances, Vol. 2, Issue 11, pp. e1601132, (2016) (PubMed).

Chen, Liu, Li, Wang, Liu, Li, Zhang, Bu: "Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation of LCAD." in: PLoS ONE, Vol. 10, Issue 3, pp. e0118909, (2015) (PubMed).

Takumida, Takumida, Katagiri, Anniko: "Localization of sirtuins (SIRT1-7) in the aged mouse inner ear." in: Acta oto-laryngologica, pp. 1-12, (2015) (PubMed).

Wei, Zhou, Qiao, Ni, Li, You, Guo, Lu: "Oroxylin A inhibits glycolysis-dependent proliferation of human breast cancer via promoting SIRT3-mediated SOD2 transcription and HIF1α destabilization." in: Cell death & disease, Vol. 6, pp. e1714, (2015) (PubMed).

Pfleger, He, Abdellatif: "Mitochondrial complex II is a source of the reserve respiratory capacity that is regulated by metabolic sensors and promotes cell survival." in: Cell death & disease, Vol. 6, pp. e1835, (2015) (PubMed).

Synonyms and alternative names related to SIRT3

sirtuin 3 (sirt3), sirtuin 3 (SIRT3), sirtuin 3 (Sirt3), 2310003L23Rik, AI848213, SIR2L3, Sir2l3, sirtuin, zgc:158774

Protein level used designations for SIRT3

  • sirtuin 3
  • sirtuin
  • NAD-dependent deacetylase sirtuin-3, mitochondrial
  • NAD-dependent protein deacetylase sirtuin-3, mitochondrial
  • SIR2-like protein 3
  • mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
  • regulatory protein SIR2 homolog 3
  • silent mating type information regulation 2, S.cerevisiae, homolog 3
  • sir2-like 3
  • sirtuin type 3
  • SIRT3 mitochondrial
  • NAD-dependent deacetylase sirtuin-3
  • NAD-dependent protein deacetylase sirtuin-3
  • SIRT3L mitochondrial
  • mSIR2L3
  • mitochondrial protein lysine deacetylase
  • silent mating type information regulation 2, (S.cerevisiae, homolog)-like 3
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