Sirtuin 6 (SIRT6) ELISA Kits

SIRT6 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Additionally we are shipping Sirtuin 6 Antibodies (211) and Sirtuin 6 Proteins (21) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SIRT6 51548 Q8N6T7
SIRT6 50721 P59941
Anti-Rat SIRT6 SIRT6 299638  
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Top Sirtuin 6 ELISA Kits at

Showing 3 out of 15 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.116 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 13 to 16 Days
Mouse 0.059 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 13 to 16 Days
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  100 Tests Log in to see 2 to 3 Days

More ELISA Kits for Sirtuin 6 Interaction Partners

Human Sirtuin 6 (SIRT6) interaction partners

  1. Thus, these results reveal that SUMOylation has an important role in regulation of Sirt6 deacetylation on H3K56, as well as its tumor suppressive activity.

  2. HBx increased signs of DNA damage such as accumulation of 8-hydroxy-2'-deoxyguanosine and comet formation, which were reversed by overexpression of PARP1 (show PARP1 ELISA Kits) and/or Sirt6..physical interaction of HBx and PARP1 (show PARP1 ELISA Kits) accelerates DNA damage by inhibiting recruitment of the DNA repair complex to the damaged DNA sites, which may lead to the onset of hepatocarcinogenesis

  3. Data suggest, in macrophages, SIRT6 plays role in preventing atherosclerosis by reducing foam cell formation via autophagy-dependent pathway involving regulation of expression of ATG5 (show ATG5 ELISA Kits), LC3B (show MAP1LC3B ELISA Kits), LAMP1 (show LAMP1 ELISA Kits), ABCA1 (show ABCA1 ELISA Kits), ABCG1 (show ABCG1 ELISA Kits), and MIRN33. (ATG5 (show ATG5 ELISA Kits) = autophagy-related protein 5 (show CAPS ELISA Kits); LC3B (show MAP1LC3B ELISA Kits) = microtubule-associated protein 1 light chain 3 beta (show MAP1LC3B ELISA Kits); LAMP1 (show LAMP1 ELISA Kits) = lysosomal-associated membrane protein 1 (show LAMP1 ELISA Kits); ABCA1 (show ABCA1 ELISA Kits)/ABCG1 (show ABCG1 ELISA Kits) = ATP-binding cassette transporters 1/8)

  4. These findings reveal a previously unknown role for nasal mucosa steady-state conditions in the control of Sirt6 activity, and provide evidence for a relationship between HMGB1 (show HMGB1 ELISA Kits) and Sirt6 in chronic rhinosinusitis with nasal polyps (CRSwNP), and promising benefits of glycyrrhetinic acid for CRSwNP patients.

  5. In obese patients, the expression of Sirt6 expression is reduced.

  6. positive regulator of aldose reductase (show AKR1B1 ELISA Kits) expression in U937 and HeLa cells under osmotic stress

  7. these results suggest that SIRT6 enhances cell aggressiveness in PTC (show F9 ELISA Kits) via BRAF (show BRAF ELISA Kits)/ERK (show EPHB2 ELISA Kits)/Mcl1 (show MCL1 ELISA Kits) pathway, and thus may be a promising target in the treatment of the disease.

  8. our studies shed insights into the crucial functions of sirtuin 6 in esophageal carcinoma cells and provide evidence supporting sirtuin 6-based personalized therapies in esophageal carcinoma cell patients

  9. SIRT6 promotes deacetylation of a new substrate, residue K18 (show KRT18 ELISA Kits) of histone H3 (show HIST3H3 ELISA Kits) (H3K18), and inactivation of SIRT6 in cells leads to H3K18 hyperacetylation and aberrant accumulation of pericentric transcripts.

  10. Data show that the increased acetylation of Ku autoantigen 70kDa (Ku70 (show XRCC6 ELISA Kits)) in sirtuin 6 protein (SIRT6)-depleted cells disrupt its interaction with Bax (show BAX ELISA Kits) apoptosis regulator protein (Bax (show BAX ELISA Kits)), which finally resulted in Bax (show BAX ELISA Kits) mitochondrial translocalization.

Cow (Bovine) Sirtuin 6 (SIRT6) interaction partners

  1. results suggest that some polymorphisms in SIRT6 are associated with production traits and may be used as candidates for marker-assisted selection (MAS (show MAS1 ELISA Kits)) and management in beef cattle breeding programs.

Mouse (Murine) Sirtuin 6 (SIRT6) interaction partners

  1. These data suggest that the function of SIRT6 in the Fabp4 (show FABP4 ELISA Kits)-Cre-expressing cells in addition to mature adipocytes plays a critical role in body weight maintenance and metabolic homeostasis.

  2. a physiological defects in adult SIRT6-/- mice

  3. In mouse retinae lacking Sirt6, effectors of glycolytic flux were dramatically increased, leading to upregulation of key intermediates in glycolysis, TCA cycle, and glutaminolysis.

  4. It has been demonstrated that Sirt6 plays a role in tooth root formation, and it was confirmed that SIRT6 is necessary for dental mesenchymal cells differentiation as well as for the development of the tooth root and for eventual tooth eruption.

  5. Fat-specific Sirt6 knockout (FKO) sensitized mice to high-fat diet-induced obesity, which was attributed to adipocyte hypertrophy rather than adipocyte hyperplasia. Fat-specific Sirt6 KO also increased inflammation in the adipose tissue, which may have contributed to insulin (show INS ELISA Kits) resistance in high-fat diet-fed FKO mice.

  6. SIRT6 is a primary negative regulation factor in endothelial dysfunction and atherosclerosis development.

  7. Data suggest that expression of Sirt6 in pancreatic beta cells protects against dysfunction (loss of hyperglycemia-induced insulin (show INS ELISA Kits) secretion) and apoptosis; Sirt6 appears to protect beta cells against the oxidative stress of diabetes type 2 and of cellular aging.

  8. SIRT6, a sirtuin (show SIRT1 ELISA Kits) with established tumor suppressor function, regulates the lysine fatty acylation of R-Ras2.

  9. data indicate that distinct activities of SIRT6 regulate different pathways and that the G60A mutant is a useful tool to study the contribution of defatty-acylase (show ACY1 ELISA Kits) activity to SIRT6's various functions

  10. Sirt6 binds to promoters of NKG2D (show KLRK1 ELISA Kits) ligand genes and regulates the H3K9 and H3K56 acetylation levels

Sirtuin 6 (SIRT6) Antigen Profile

Antigen Summary

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with Sirtuin 6 (SIRT6) ELISA Kits

  • sirtuin 6 (sirt6) antibody
  • sirtuin 6 (SIRT6) antibody
  • sirtuin 6 (Sirt6) antibody
  • 2810449N18Rik antibody
  • AI043036 antibody
  • Sir2l6 antibody

Protein level used designations for Sirtuin 6 (SIRT6) ELISA Kits

sirtuin (silent mating type information regulation 2 homolog) 6 , NAD-dependent deacetylase sirtuin-6 , NAD-dependent protein deacetylase sirtuin-6 , SIR2-like protein 6 , regulatory protein SIR2 homolog 6 , sir2-related protein type 6 , sirtuin type 6

444018 Xenopus laevis
428332 Gallus gallus
51548 Homo sapiens
485045 Canis lupus familiaris
100126274 Sus scrofa
535416 Bos taurus
50721 Mus musculus
299638 Rattus norvegicus
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