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Sirtuin 6 (SIRT6) ELISA Kits

SIRT6 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Additionally we are shipping Sirtuin 6 Antibodies (213) and Sirtuin 6 Proteins (24) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SIRT6 51548 Q8N6T7
SIRT6 50721 P59941
Anti-Rat SIRT6 SIRT6 299638  
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Top Sirtuin 6 ELISA Kits at

Showing 3 out of 14 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.115 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
Mouse 0.059 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
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  100 Tests Log in to see 2 to 3 Days

More ELISA Kits for Sirtuin 6 Interaction Partners

Human Sirtuin 6 (SIRT6) interaction partners

  1. SIRT6, TNF-alpha (show TNF ELISA Kits), and IFN-gamma (show IFNG ELISA Kits) were significantly higher in lesional than perilesional and control skin.

  2. this study shoes that through the antiglycolytic activity of SIRT6, the autophagy is suppressed, which is beneficial to nasal polyp formation

  3. The promoter regions of the SIRT6 gene were genetically analyzed in large cohorts of MI patients (n = 371) and ethnically-matched controls (n = 383). Results: A total of 15 DNA sequence variants (DSVs) were identified, including seven single-nucleotide polymorphisms (SNPs). Two novel heterozygous DSVs, g.4183823G>C and g.4183742G>A, were identified in two MI patients but in none of the controls.

  4. we examined the role and mechanisms of SIRT6 in suppressing postoperative epidural scar formation. We showed that SIRT6 promoted the expression of miR (show MLXIP ELISA Kits)-21 and then suppressed TGF-beta2 (show TGFB2 ELISA Kits) expression in a targeted manner.

  5. SIRT6 induced autophagy via attenuation of AKT signaling and treatment with autophagy inhibitor 3-MA or knockdown of autophagy-related protein Atg5 rescued H2O2-induced neuronal injury.

  6. Data indicate that compared to non-neoplastic endometria (NNE (show ENO1 ELISA Kits)), endometrial cancer (EC) showed SIRT7 (show SIRT7 ELISA Kits) mRNA overexpression, whereas SIRT1 (show SIRT1 ELISA Kits), SIRT2 (show SIRT2 ELISA Kits), SIRT4 (show SIRT4 ELISA Kits) and SIRT5 (show SIRT5 ELISA Kits) were underexpressed, and no significant differences were observed for SIRT3 (show SIRT3 ELISA Kits) and SIRT6.

  7. SIRT6 as an important pancreatic ductal adenocarcinoma tumor suppressor

  8. Tissue micro-array studies confirmed the higher levels of SIRT6 in both prostate tumor tissues and prostate cancer cells than in their normal counterparts. Knockdown of SIRT6 in human prostate cancer cells led to sub-G1 phase arrest of cell cycle, increased apoptosis, elevated DNA damage level and decrease in BCL2 (show BCL2 ELISA Kits) gene expression.

  9. Results find no significant association between common polymorphisms and haplotypes in the SIRT6 gene and longevity.

  10. Data provided evidence that SIRT6 tagSNPs rs352493 and rs3760908 play significant roles in the severity of coronary artery disease (CAD (show CAD ELISA Kits)) in Chinese Han subjects, which might be useful predictors of the severity of CAD (show CAD ELISA Kits).

Cow (Bovine) Sirtuin 6 (SIRT6) interaction partners

  1. results suggest that some polymorphisms in SIRT6 are associated with production traits and may be used as candidates for marker-assisted selection (MAS (show MAS1 ELISA Kits)) and management in beef cattle breeding programs.

Mouse (Murine) Sirtuin 6 (SIRT6) interaction partners

  1. Sirt6 binds to promoters of NKG2D (show KLRK1 ELISA Kits) ligand genes and regulates the H3K9 and H3K56 acetylation levels

  2. The critical role of SIRT6 on aging and inflammation.

  3. The SIRT6 regulates HSC (show FUT1 ELISA Kits) homeostasis through the transcriptional repression of Wnt (show WNT2 ELISA Kits) target genes. Sirt6 deletion promoted HSC (show FUT1 ELISA Kits) proliferation through aberrant activation of Wnt (show WNT2 ELISA Kits) signaling.

  4. Sirt6 plays a crucial role in dendritic cell differentiation and function and reduced Sirt6 activity may contribute to immunosenescence.

  5. up-regulates AMP (show TMPRSS5 ELISA Kits)/ATP and then activates the AMPK (show PRKAA1 ELISA Kits)-FoxO3alpha axis and further initiates the downstream antioxidant-encoding gene expression, thereby decreasing cellular levels of oxidative stress and mediating cardioprotection in the ischemic heart

  6. SIRT6 is important for glucose-stimulated insulin (show INS ELISA Kits) secretion from pancreatic beta cells and activation of SIRT6 may be useful to improve insulin (show INS ELISA Kits) secretion in diabetes

  7. These data strongly suggest that overexpression of Sirt6 can prevent osteoarthritis development by reducing both the inflammatory response and chondrocytes senescence.

  8. Sirt6 depletion causes spindle defects and chromosome misalignment during meiosis of mouse oocyte

  9. In SIRT6-deficient mice there is impaired bone remodeling leading to osteopenia.

  10. SIRT6/NF-kappaB (show NFKB1 ELISA Kits) signaling axis in ginsenoside Rg1 (show PPP1R3A ELISA Kits)-delayed hematopoietic stem/progenitor cell senescence.

Sirtuin 6 (SIRT6) Antigen Profile

Antigen Summary

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with Sirtuin 6 (SIRT6) ELISA Kits

  • sirtuin 6 (sirt6) antibody
  • sirtuin 6 (SIRT6) antibody
  • sirtuin 6 (Sirt6) antibody
  • 2810449N18Rik antibody
  • AI043036 antibody
  • Sir2l6 antibody

Protein level used designations for Sirtuin 6 (SIRT6) ELISA Kits

sirtuin (silent mating type information regulation 2 homolog) 6 , NAD-dependent deacetylase sirtuin-6 , NAD-dependent protein deacetylase sirtuin-6 , SIR2-like protein 6 , regulatory protein SIR2 homolog 6 , sir2-related protein type 6 , sirtuin type 6

444018 Xenopus laevis
428332 Gallus gallus
51548 Homo sapiens
485045 Canis lupus familiaris
100126274 Sus scrofa
535416 Bos taurus
50721 Mus musculus
299638 Rattus norvegicus
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