(Sirtuin 6 (SIRT6))
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Latest Publications for our SIRT6 products: "Protective effects of SIRT6 against lipopolysaccharide (LPS) are mediated by deacetylation of Ku70." in: Molecular immunology, Vol. 101, pp. 312-318, (2019) (PubMed).
: "SIRT6 Depletion Sensitizes Human Hepatoma Cells to Chemotherapeutics by Downregulating MDR1 Expression." in: Frontiers in pharmacology, Vol. 9, pp. 194, (2018) (PubMed).
: "SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability." in: Nature communications, Vol. 7, pp. 12235, (2018) (PubMed).
: "Downregulation of SIRT6 is associated with poor prognosis in patients with non-small cell lung cancer." in: The Journal of international medical research, Vol. 46, Issue 4, pp. 1517-1527, (2018) (PubMed).
: "Deacetylation of Ku70 by SIRT6 attenuates Bax-mediated apoptosis in hepatocellular carcinoma." in: Biochemical and biophysical research communications, Vol. 485, Issue 4, pp. 713-719, (2017) (PubMed).
: "SIRT6 Overexpression Potentiates Apoptosis Evasion in Hepatocellular Carcinoma via BCL2-Associated X Protein-Dependent Apoptotic Pathway." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 13, pp. 3372-82, (2016) (PubMed).
: "Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating Sirtuin." in: Scientific reports, Vol. 5, pp. 12012, (2015) (PubMed).
: "SIRT6 expression is associated with poor prognosis and chemosensitivity in patients with non-small cell lung cancer." in: Journal of surgical oncology, Vol. 112, Issue 2, pp. 231-7, (2015) (PubMed).
: "Epigenetic modulation of chronic anxiety and pain by histone deacetylation." in: Molecular psychiatry, Vol. 20, Issue 10, pp. 1219-31, (2015) (PubMed).
: "Biochemical characterization of sirtuin 6 in the brain and its involvement in oxidative stress response." in: Neurochemical research, Vol. 40, Issue 1, pp. 59-69, (2015) (PubMed).
Synonyms and alternative names related to SIRT6sirtuin 6 (Sirt6), sirtuin 6 (SIRT6), sirtuin 6 S homeolog (sirt6.S), sirtuin 6 (sirt6), 2810449N18Rik, AI043036, Sir2l6, SIR2L6, zgc:86729
Protein level used designations for SIRT6
- NAD-dependent deacetylase sirtuin-6
- NAD-dependent protein deacetylase sirtuin-6
- SIR2-like protein 6
- regulatory protein SIR2 homolog 6
- sir2-related protein type 6
- sirtuin type 6
- sirtuin (silent mating type information regulation 2 homolog) 6
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