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anti-Sphingosine-1-Phosphate Receptor 2 (S1PR2) Antibodies

S1PR2 encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. Additionally we are shipping S1PR2 Kits (7) and S1PR2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
S1PR2 9294 O95136
S1PR2 14739 P52592
S1PR2 29415 P47752
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Top anti-S1PR2 Antibodies at

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Goat Un-conjugated EIA, WB AP21513PU-N S1PR2 Antibody staining of Human Frontal Cortex lysate at 0.5 µg/ml (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated EIA, IF, WB 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
Human Mouse Un-conjugated FACS Detection of S1P2/EDG-5 in HEK293 Human Cell Line Transfected with Human S1P2/EDG-5 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) human S1P2/EDG-5 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human S1P2/EDG-5 Monoclonal Antibody. 100 μg Log in to see 6 to 7 Days
Dog Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Log in to see 14 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from COLO205 cells, using EDG5 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB S1PR2 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the S1PR2 antibody detected the S1PR2 protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of EDG5 staining in Hela cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody i Immunohistochemical analysis of EDG5 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the an 200 μL Log in to see 9 Days

S1PR2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
, ,
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Mouse (Murine)

Rat (Rattus)

Top referenced anti-S1PR2 Antibodies

  1. Human Polyclonal S1PR2 Primary Antibody for IF, IHC (p) - ABIN317633 : Danieli-Betto, Peron, Germinario, Zanin, Sorci, Franzoso, Sandonà, Betto: Sphingosine 1-phosphate signaling is involved in skeletal muscle regeneration. in American journal of physiology. Cell physiology 2010 (PubMed)
    Show all 2 references for ABIN317633

  2. Dog (Canine) Polyclonal S1PR2 Primary Antibody for EIA, WB - ABIN568703 : McGeachie, Ramoni, Mychaleckyj, Furie, Dreyfuss, Liu, Herrington, Guo, Lima, Post, Rotter, Rich, Sale, Ramoni: Integrative predictive model of coronary artery calcification in atherosclerosis. in Circulation 2009 (PubMed)

  3. Human Monoclonal S1PR2 Primary Antibody for FACS - ABIN4899079 : Capitani, Patrussi, Trentin, Lucherini, Cannizzaro, Migliaccio, Frezzato, Gattazzo, Forconi, Pelicci, Semenzato, Baldari: S1P1 expression is controlled by the pro-oxidant activity of p66Shc and is impaired in B-CLL patients with unfavorable prognosis. in Blood 2012 (PubMed)

  4. Human Polyclonal S1PR2 Primary Antibody for EIA, IF - ABIN317746 : Huang, Liu, Lan, Xie, Peng, Huang, Wang, Shen, Liu, Huang: Berberine reduces fibronectin expression by suppressing the S1P-S1P2 receptor pathway in experimental diabetic nephropathy models. in PLoS ONE 2012 (PubMed)

More Antibodies against S1PR2 Interaction Partners

Human Sphingosine-1-Phosphate Receptor 2 (S1PR2) interaction partners

  1. S1PR2 mediates Rho activation in normal cells neighboring RasV12-transformed cells.

  2. Sphingosine 1-phosphate-induced IL-8 (show IL8 Antibodies) gene expression is mainly regulated via S1PR(1 (show S1PR1 Antibodies)), and its secretion is regulated through S1PR(2) receptor subtype.

  3. S1PR2 is repressed by FOXP1 (show FOXP1 Antibodies) in activated B-cell and germinal center B-cell DLBCL cell lines with aberrantly high FOXP1 (show FOXP1 Antibodies) levels; S1PR2 expression is further inversely correlated with FOXP1 (show FOXP1 Antibodies) expression in 3 DLBCL patient cohorts.

  4. LXR-alpha (show NR1H3 Antibodies) might downregulate S1PR2 expression via miR (show MLXIP Antibodies)-130a-3p in quiescent HUVECs. Stimulation of TNF-alpha (show TNF Antibodies) attenuates the activity of LXR-alpha (show NR1H3 Antibodies) and results in enhanced S1PR2 expression.

  5. S1PR2 plays a critical role in TCA-induced COX-2 (show COX2 Antibodies) expression and CCA (show FBN2 Antibodies) growth and may represent a novel therapeutic target for CCA (show FBN2 Antibodies).

  6. both S1PR1 (show S1PR1 Antibodies) and S1PR2 play a pivotal role in hyperglycemia-induced EC dysfunction and endothelial injury by reducing and enhancing the production of oxidative stress.

  7. AB1 displayed potency at least equivalent to JTE-013 in affecting signaling molecules downstream of S1P2.

  8. Activation of S1PR2-calcium influx-RhoA (show RHOA Antibodies)/ROCK dominates the high-dose S1P (show MBTPS1 Antibodies)-induced endothelial monolayer hyperpermeability response.

  9. Data show that sphingosine kinase SphK1 (show SPHK1 Antibodies) and sphingosine-1-phosphate (S1P (show MBTPS1 Antibodies)) receptors S1P1 (show S1PR1 Antibodies), S1P2, S1P3 (show S1PR3 Antibodies), and S1P5 (show S1PR5 Antibodies) were expressed from primary, up to recurrent and secondary glioblastomas, with sphingosine kinase SphK2 (show SPHK2 Antibodies) levels were highest in primary tumors.

  10. Data indicate that sphingosine 1-phosphate (S1P (show MBTPS1 Antibodies)) and hepatocyte growth factor (HGF (show HGF Antibodies)) induced transloaction of integrin beta4, S1P (show MBTPS1 Antibodies) receptors S1PR2 and S1PR3 (show S1PR3 Antibodies) to endothelial cell membrane caveolin-enriched microdomains (CEMs).

Mouse (Murine) Sphingosine-1-Phosphate Receptor 2 (S1PR2) interaction partners

  1. activation of S1P2 with a selective receptor agonist increases cell viability and reduces cisplatin-mediated cell death by reducing ROS (show ROS1 Antibodies). Cumulatively, these results suggest that S1P2 may serve as a therapeutic target for attenuating cisplatin-mediated ototoxicity.

  2. S1P2 receptor is a key signaling molecule in the S1Pdependent inhibition of adipogenic differentiation.

  3. S1PR2, as a critical receptor in macrophages, impairs phagocytosis and antimicrobial defense in the pathogenesis of sepsis.

  4. These results suggest that S1PR2 and CXCR5 (show CXCR5 Antibodies) cooperatively regulate localization of Tfh cells in GCs (show UGCG Antibodies) to support GC responses

  5. The sphingolipid receptor S1PR2 is a receptor for Nogo-a (show RTN4 Antibodies) repressing synaptic plasticity.

  6. S1PR2 expression was increased in disease-susceptible regions of the CNS of female SJL EAE mice compared with their male counterparts.

  7. IL-6 (show IL6 Antibodies) increased the number of osteoclast precursor cells in tibial bone marrow via up-regulating S1PR2, thus playing a crucial role in systemic bone loss induced by inflammation.

  8. Sphingosine-1-phosphate receptor 2 protects against anaphylactic shock through suppression of endothelial nitric oxide synthase (show NOS3 Antibodies) in mice.

  9. Data show that two S1P (show S1PR1 Antibodies) receptors, S1P2 and S1P3 (show S1PR3 Antibodies), are collectively essential mediators of eyelid closure during murine development.

  10. S1PR2 is a key regulator of the proinflammatory phenotype of the endothelium.

S1PR2 Antigen Profile

Protein Summary

This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. This protein participates in sphingosine 1-phosphate-induced cell proliferation, survival, and transcriptional activation

Gene names and symbols associated with S1PR2

  • sphingosine-1-phosphate receptor 2 (S1PR2) antibody
  • sphingosine-1-phosphate receptor 2 (S1pr2) antibody
  • 1100001A16Rik antibody
  • AGR16 antibody
  • EDG-5 antibody
  • Edg5 antibody
  • Gpcr13 antibody
  • GPCR18 antibody
  • H218 antibody
  • LPb2 antibody
  • S1P2 antibody
  • snGPCR18 antibody

Protein level used designations for S1PR2

sphingosine-1-phosphate receptor 2 , sphingosine 1-phosphate receptor 2-like , S1P receptor 2 , S1P receptor EDG5 , S1P receptor Edg-5 , endothelial differentiation G-protein coupled receptor 5 , endothelial differentiation, sphingolipid G-protein-coupled receptor, 5 , sphingosine 1-phosphate receptor 2 , sphingosine 1-phosphate receptor Edg-5 , G-protein coupled receptor 13 , lysophospholipid receptor B2 , sphingosine-1-phosphate receptor S1P(2) , AGR16 , G-protein coupled receptor H218 , S1P2

100392405 Callithrix jacchus
100435839 Pongo abelii
100610932 Pan troglodytes
9294 Homo sapiens
14739 Mus musculus
29415 Rattus norvegicus
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