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Sacsin Antibodies

(Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS))
This gene encodes the sacsin protein, which includes a UbL domain at the N-terminus, a DnaJ domain, and a HEPN domain at the C-terminus. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. This gene includes a very large exon spanning more than 12.8 kb. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), a neurodegenerative disorder characterized by early-onset cerebellar ataxia with spasticity and peripheral neuropathy. The authors of a publication on the effects of siRNA-mediated sacsin knockdown concluded that sacsin protects against mutant ataxin-1 and suggest that 'the large multi-domain sacsin protein is able to recruit Hsp70 chaperone action and has the potential to regulate the effects of other ataxia proteins' (Parfitt et al., PubMed: 19208651). [provided by RefSeq, Apr 2012].
anti-Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS) (AA 3709-3909) antibody anti-Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS) (AA 3709-3909) antibody anti-Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS) (AA 3709-3909) antibody (ABIN5693301)

SACS Reactivity: Human, Mouse, Rat ELISA, IHC, WB Host: Rabbit Polyclonal unconjugated

anti-Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS) antibody anti-Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS) antibody anti-Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS) antibody (ABIN5708501)

SACS Reactivity: Human, Mouse, Rat ELISA, IHC (p), WB Host: Rabbit Polyclonal unconjugated

Sacsin Antibodies by Reactivity

Find Sacsin Antibodies for a variety of species such as anti-Human Sacsin, anti-Mouse Sacsin, anti-Rat Sacsin. The species listed below are among those available. Click on a link to go to the corresponding products.

Sacsin Antibodies by Application

Find Sacsin Antibodies validated for a specific application such as ELISA, IHC, WB, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

Sacsin Antibodies by Host

Find Sacsin Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

Sacsin Antibodies by Binding Specificity

Find Sacsin Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Sacsin Antibodies by Clonality

Find available monoclonal or polyclonal Sacsin Antibodies. Click on a link to go to the corresponding products.

Sacsin Antibodies by Conjugate

Find Sacsin Antibodies with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Sacsin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IF, IHC
Validations
Cat. No. ABIN7168566
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7168567
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7168568
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC (p)
Validations
Cat. No. ABIN6390208
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
Cat. No. ABIN7119378
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN5673657
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN6113843
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC
Validations
Cat. No. ABIN1982323
Quantity 50 μg
Datasheet Datasheet

Aliases for Sacsin Antibodies

sacsin (Sacs) Antibodies
sacsin molecular chaperone (SACS) Antibodies
A230052M14 Antibodies
ARSACS Antibodies
DNAJC29 Antibodies
E130115J16Rik Antibodies
mKIAA0730 Antibodies
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