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TEA Domain Family Member 4 Proteins (TEAD4)

TEAD4 product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. Additionally we are shipping TEAD4 Antibodies (63) and TEAD4 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TEAD4 7004 Q15561
TEAD4 21679 Q62296
Rat TEAD4 TEAD4 683522  
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Top TEAD4 Proteins at

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days

TEAD4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine)

Top referenced TEAD4 Proteins

  1. Human TEAD4 Protein expressed in Wheat germ - ABIN1322450 : Fujii, Toyoda, Nakanishi, Yatabe, Sato, Matsudaira, Ito, Murakami, Kondo, Kondo, Hida, Tsujimura, Osada, Sekido: TGF-? synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growth. in The Journal of experimental medicine 2012 (PubMed)

More Proteins for TEA Domain Family Member 4 (TEAD4) Interaction Partners

Xenopus laevis TEA Domain Family Member 4 (TEAD4) interaction partners

  1. the transcriptional regulators in the Hippo pathway, Tead4 and Yap1 (show YAP1 Proteins), are required for general vertebrate epimorphic regeneration as well as for organ size control in appendage regeneration

Human TEA Domain Family Member 4 (TEAD4) interaction partners

  1. TEAD4 and KLF5 (show KLF5 Proteins), in collaboration, promoted triple negative breast cancer cell proliferation and tumor growth in part by inhibiting p27 (show PAK2 Proteins) gene transcription

  2. potential anti-oxidation gene and can prevent H2O2-induced endothelial cell oxidative damage by activating Klotho (show KL Proteins)

  3. TEAD4 overexpression induced p16 in HAoSMCs homozygous for the nonrisk coronary disease allele, but not for the risk allele.

  4. TAZ (show TAZ Proteins) negatively regulate transcription of DeltaNp63 through TEAD1,2,3 and 4 transcription factors.

  5. Our findings suggest that genetic variants of Hippo pathway genes, particularly YAP1 (show YAP1 Proteins) rs11225163, TEAD1 (show TEAD1 Proteins) rs7944031 and TEAD4 rs1990330, may independently or jointly modulate survival of CM patients.

  6. the peptides TEF3 (show TRIM37 Proteins)-11-66 and TEF3 (show TRIM37 Proteins)-1197-434 functioned as two independent activation domains, suggesting that N-terminal domain of TEF3 (show TRIM37 Proteins)-1 also has transcriptional activation capacity

  7. Edg-1 (show HEXIM1 Proteins) is a potential target gene of RTEF-1 and is involved in RTEF-1-induced angiogenesis in endothelial cells.

  8. the multilevel perturbations of TEAD4 at epigenetic, transcriptional and posttranslational levels may contribute to GC development.

  9. These data suggest that TFF3 (show TFF3 Proteins) and survivin (show BIRC5 Proteins) expressions play a vital role in gastric cancer development, and these two proteins are important markers for prognosis in gastric cancer.

  10. convergent optimization of the YAP (show YAP1 Proteins)/TAZ (show TAZ Proteins) TEAD binding site suggests that the similarity in the affinities of binding of YAP (show YAP1 Proteins) to TEAD and of TAZ (show TAZ Proteins) to TEAD is important for Hippo pathway functionality.

Mouse (Murine) TEA Domain Family Member 4 (TEAD4) interaction partners

  1. Dual-luciferase reporter gene analysis showed that RTEF-1 is a direct target of mir-125a-5p, which regulates angiogenesis by repressing RTEF-1 expression and modulating eNOS and VEGF expression.

  2. TEAD4 establishes the energy homeostasis essential for blastocoel formation.

  3. These results show that RTEF-1-stimulated IGFBP-1 (show IGFBPI Proteins) expression may be central to the mechanism by which RTEF-1 attenuates blood glucose levels.

  4. Vgll1 (show VGLL1 Proteins) interacts with TEAD4 in a manner similar to the transcription coactivators, as well as oncogenes YAP (show YAP1 Proteins) and TAZ (show TAZ Proteins), despite having a varied primary sequence. Vgll1 (show VGLL1 Proteins) has the potential to promote cancer progression.

  5. endothelial-specific RTEF-1 overexpressing mice had enhanced angiogenic sprouting and vascular structure remodeling, resulting in the formation of a denser and more highly interconnected superficial capillary plexus

  6. Data suggest that altered subcellular localization of TEAD4 in blastomeres dictates first mammalian cell fate specification.

  7. TEAD factors directly induce Myogenin (show MYOG Proteins), CDKN1A (show CDKN1A Proteins) and Caveolin 3 (show CAV3 Proteins) expression to promote myoblast differentiation.

  8. Gata3 (show GATA3 Proteins) and Cdx2 (show CDX2 Proteins) can act in parallel pathways downstream of Tead4 to induce the expression of common and independent targets in the trophoblast lineage, whereas Oct4 (show POU5F1 Proteins) is required for continued repression of trophoblast fate in the embryonic lineage

  9. Novel RTEF-1 transcripts are present within human ocular vascular endothelial cells and mouse neural retina during normal and retinopathy of prematurity development, and alternatively spliced products are produced under hyperoxic and hypoxic conditions

  10. RTEF-1 regulated smooth muscle alpha-actin (show ACTA2 Proteins) transcription in myofibroblasts, but not in differentiated smooth muscle

TEAD4 Protein Profile

Protein Summary

This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene.

Gene names and symbols associated with TEAD4

  • TEA domain family member 4 (TEAD4)
  • TEA domain family member 4 (tead4)
  • TEA domain family member 4 (Tead4)
  • EFTR-2 protein
  • ETFR-2 protein
  • Etfr2 protein
  • FR-19 protein
  • hRTEF-1B protein
  • RTEF-1 protein
  • RTEF1 protein
  • TCF13L1 protein
  • Tcf13r1 protein
  • TEAD-4 protein
  • TEAD4 protein
  • TEF-1 protein
  • TEF-3 protein
  • Tef3 protein
  • Tefr protein
  • TEFR-1 protein
  • Tefr1 protein
  • Tefr1a protein
  • xdtef-1 protein
  • xlDTEF-1 protein

Protein level used designations for TEAD4

TEA domain family member 4 , M-CAT binding factor , M-CAT-binding factor , TEAD-4 , transcriptional enhancer factor TEF-3 , related transcription enhancer factor 1B , transcription factor 13-like 1 , transcription factor RTEF-1 , transcriptional enhancer factor 1-related , transcriptional enhancer factor 3 , transcriptional enhancer factor 1-related protein , ETF-related factor 2 , ETF-related factor-2 , FGF-regulated 19 , RTEF-1 , TEF-1-related factor 1 , TEF-1-related factor FR-19

451756 Pan troglodytes
100144667 Xenopus (Silurana) tropicalis
447700 Xenopus laevis
395542 Gallus gallus
7004 Homo sapiens
611826 Canis lupus familiaris
100152085 Sus scrofa
526771 Bos taurus
21679 Mus musculus
683522 Rattus norvegicus
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