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Tafazzin Proteins (TAZ)

TAZ encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Additionally we are shipping TAZ Antibodies (134) and TAZ Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TAZ 6901 Q16635
TAZ 66826  
TAZ 363521  
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Top TAZ Proteins at

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 0.5 mg Log in to see 49 to 54 Days
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Primates His tag   1 mg Log in to see 56 to 66 Days
Yeast Macaca mulatta His tag   1 mg Log in to see 56 to 66 Days
Yeast Primate His tag   1 mg Log in to see 56 to 66 Days
Yeast Pongo pygmaeus His tag   1 mg Log in to see 56 to 66 Days
Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days

TAZ Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Tafazzin (TAZ) Interaction Partners

Zebrafish Tafazzin (TAZ) interaction partners

  1. Taz is required in the anteroposterior patterning of the pronephric progenitor domain in the intermediate mesoderm, acting in part by regulating retinoic acid signaling in the pronephric progenitor field in the intermediate mesoderm.

  2. Taz-depleted larvae displayed patterning defects in ventral cranial vessels that correlate with lateral displacement of thyroid follicles.

  3. Yap (show YAP1 Proteins)/Taz-Tead activity is necessary and sufficient for optic vesicle progenitors to adopt retinal pigment epithelium identity in zebrafish.

  4. When transcriptional coactivators Yap (show YAP1 Proteins) and Taz were restricted from interacting with Tead transcription factors through expression of a dominant negative transgene, cardiac precursors failed to migrate completely to the midline.

  5. knockdown phenotype demonstrates that abnormal cardiac development, with a linear, nonlooped heart, and hypomorphic tail and eye development proves that tafazzin is essential for overall zebrafish development, especially of the heart.

Human Tafazzin (TAZ) interaction partners

  1. these data reveal a previously unknown role for TAZ and the Hippo pathway in the progression of aggressive subtypes of endometrial cancer.

  2. two novel and non-identical TAZ gene rearrangements were found in the offspring of a single female carrier of Barth syndrome.

  3. The TAZ play an essential role in amino acid-induced mTORC1 activation, particularly under nutrient-limiting conditions.

  4. factor:TAZ transcriptional co-activator and activation of sE-Cadherin/proto-oncogene (show RAB1A Proteins) protein HER-2 (show ERBB2 Proteins) signaling could be potential oncogenic pathways for breast cancer (BC) metastasis.

  5. preS2 upregulates TAZ expression by repressing miRNA-338-3p. TAZ is necessary for preS2-promoted HCC (show FAM126A Proteins) proliferation and migration.

  6. Actin remodeling confers BRAF (show BRAF Proteins) inhibitor resistance to melanoma cells through YAP (show YAP1 Proteins)/TAZ activation

  7. Data suggest that activation of TAZ (tafazzin) inhibits adipogenesis in mesenchymal stem cells; interaction of TAZ and protein phosphatases (PP1A (show PPP1CA Proteins), PP2A (show PPP2R4 Proteins)) up-regulates dephosphorylation and transport of TAZ to cell nucleus.

  8. Our findings elucidate the mechanistic basis of the oncogenic properties of TAZ-CAMTA1 fusion

  9. Results revealed that TAZ is a differentially expressed molecule in human hepatocellular carcinoma (HCC (show FAM126A Proteins)) suggesting it as an important regulator, TAZ might be as a new diagnostic biomarker in HCC (show FAM126A Proteins).

  10. Suggest that high expression of TAZ plays a significant role in retinoblastoma's aggressiveness, and predicts poor prognosis for patients with retinoblastoma.

Mouse (Murine) Tafazzin (TAZ) interaction partners

  1. These findings uncover important roles for Yap (show YAP1 Proteins) and Taz in cranial neural crest diversification and development.

  2. The impact of endurance training on the cardiac and skeletal muscle phenotype in young TAZ knock-down mice.

  3. impaired Taz-function with onset at adult age does not enhance susceptibility to ischemia-reperfusion injury.

  4. Study discovered Ythat AP/TAZ are bona fide downstream effectors of the alternative Wnt (show WNT2 Proteins) signaling pathway.

  5. A novel role for Taz in helping to maintain genome integrity in spermatocyte meiosis and facilitating germ cell differentiation.

  6. Hippo signalling effectors, YAP (show YAP1 Proteins) and TAZ, promote both the proliferation of intestinal stem/progenitor cells and their differentiation into goblet cells.

  7. Tafazzin deficiency in mouse embryonic fibroblasts also led to impaired oxidative phosphorylation and severe oxidative stress

  8. This study identifies a novel mechanism of TAZ regulation by YAP (show YAP1 Proteins), which has significant implications for our understanding of Hippo pathway regulation, YAP (show YAP1 Proteins)-isoform specific signaling, and the role of these proteins in cell proliferation, apoptosis, and tumorigenesis.

  9. YAP (show YAP1 Proteins)/TAZ regulate transcriptional elongation from the enhancer elements by recruiting the Mediator complex and promoting phenotypes of overgrowth and tumorigenesis.

  10. Expression of TAZ promotes embryonic neural stem cell maintenance by enhancing stemness of neural stem cells during mammalian brain development.

TAZ Protein Profile

Protein Summary

This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced\; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.

Gene names and symbols associated with Tafazzin Proteins (TAZ)

  • tafazzin (TAZ)
  • tafazzin (taz)
  • tafazzin (Taz)
  • tafazzin (AFUA_2G13960)
  • tafazzin (AOR_1_318014)
  • tafazzin (Tsp_06712)
  • Tafazzin (taz)
  • 5031411C02Rik protein
  • 9130012G04Rik protein
  • Afu2g13960 protein
  • AW107266 protein
  • AW552613 protein
  • BTHS protein
  • CMD3A protein
  • EFE protein
  • EFE2 protein
  • G4.5 protein
  • GB11956 protein
  • LVNCX protein
  • MGC54019 protein
  • taz protein
  • Taz1 protein
  • wu:fb39f12 protein
  • zgc:91803 protein

Protein level used designations for Tafazzin Proteins (TAZ)

tafazzin , Tafazzin , protein G4.5 , Barth syndrome) , endocardial fibroelastosis 2 , tafazzin (cardiomyopathy, dilated 3A (X-linked) , tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome)

100446947 Pongo abelii
321965 Danio rerio
379259 Xenopus laevis
515177 Bos taurus
549220 Xenopus (Silurana) tropicalis
550948 Apis mellifera
3513201 Aspergillus fumigatus Af293
5993687 Aspergillus oryzae RIB40
10911739 Trichinella spiralis
100137265 Papio anubis
100196028 Salmo salar
100328759 Oryctolagus cuniculus
100528715 Ictalurus punctatus
6901 Homo sapiens
66826 Mus musculus
363521 Rattus norvegicus
612975 Canis lupus familiaris
449590 Pan troglodytes
574297 Macaca mulatta
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