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Tafazzin Proteins (TAZ)

TAZ encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Additionally we are shipping TAZ Antibodies (132) and TAZ Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TAZ 6901 Q16635
TAZ 66826  
TAZ 363521  
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Top TAZ Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$827.20
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$1,073.60
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Primates His tag   1 mg Log in to see 56 to 66 Days
$2,678.50
Details
Yeast Primate His tag   1 mg Log in to see 56 to 66 Days
$2,678.50
Details
Yeast Macaca mulatta His tag   1 mg Log in to see 56 to 66 Days
$2,678.50
Details
Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days
$2,772.00
Details
Yeast Pongo pygmaeus His tag   1 mg Log in to see 56 to 66 Days
$2,772.00
Details

TAZ Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Tafazzin (TAZ) Interaction Partners

Zebrafish Tafazzin (TAZ) interaction partners

  1. knockdown phenotype demonstrates that abnormal cardiac development, with a linear, nonlooped heart, and hypomorphic tail and eye development proves that tafazzin is essential for overall zebrafish development, especially of the heart.

Human Tafazzin (TAZ) interaction partners

  1. two novel and non-identical TAZ gene rearrangements were found in the offspring of a single female carrier of Barth syndrome.

  2. Tafazzin deficiency in mouse embryonic fibroblasts also led to impaired oxidative phosphorylation and severe oxidative stress

  3. ability of CL-ND to elicit a physiological response was examined in an HL60 cell culture model of Barth Syndrome neutropenia. siRNA knockdown of the phospholipid transacylase, tafazzin (TAZ), induced apoptosis in these cells

  4. novel mutation in exon 1 of the TAZ gene and female mosaicism in three generations of a Polish family with Barth syndrome

  5. mitochondria-targeted antioxidant prevents cardiac dysfunction induced by tafazzin gene knockdown in cardiac myocytes

  6. Strong expression of TAZ protein seems to be related to rectal cancer development and RT response, it can be a predictive biomarker of distant recurrence in patients with preoperative RT.

  7. Three novel hemizygous mutations in the TAZ gene were found (c.584G>T; c.109+6T>C; c.86G>A). We conclude that Barth syndrome should be included in differential diagnosis of cardiomyopathy in childhood.

  8. Results show that in both healthy controls and in Barth syndrome patients, a greater variety of alternatively spliced forms than previously described was found. It includes a sizeable proportion of minor splice variants besides the four dominant isoforms.

  9. data suggest that genes other than G4.5 are responsible for the familial form of noncompaction of the ventricular myocardium

  10. study reports five new TAZ gene mutations in six unrelated Barth Syndrome patients, including two new gross gene rearrangements

Mouse (Murine) Tafazzin (TAZ) interaction partners

  1. The impact of endurance training on the cardiac and skeletal muscle phenotype in young TAZ knock-down mice.

  2. impaired Taz-function with onset at adult age does not enhance susceptibility to ischemia-reperfusion injury.

  3. A novel role for Taz in helping to maintain genome integrity in spermatocyte meiosis and facilitating germ cell differentiation.

  4. Tafazzin deficiency in mouse embryonic fibroblasts also led to impaired oxidative phosphorylation and severe oxidative stress

  5. TAZ mutation is necessary and sufficient for the phenotype of sparse and irregular sarcomeres and weak myocaridal contraction foudn in Barth syndrome.

  6. Tafazzin knockdown mice provide a mammalian model system for Barth syndrome in which the pathophysiological relationships between altered content of mitochondrial phospholipids, ultrastructural abnormalities, myocardial and mitochondrial dysfunction

  7. The data suggest that tafazzin deficiency affects cardiolipin in all mitochondria, but significant alterations of the ultrastructure, such as remodeling and aggregation of inner membranes, will only occur after specific differentiation.

TAZ Protein Profile

Protein Summary

This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced\; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.

Gene names and symbols associated with Tafazzin Proteins (TAZ)

  • tafazzin (TAZ)
  • tafazzin (taz)
  • tafazzin (Taz)
  • tafazzin (AFUA_2G13960)
  • tafazzin (AOR_1_318014)
  • tafazzin (Tsp_06712)
  • Tafazzin (taz)
  • 5031411C02Rik protein
  • 9130012G04Rik protein
  • Afu2g13960 protein
  • AW107266 protein
  • AW552613 protein
  • BTHS protein
  • CMD3A protein
  • EFE protein
  • EFE2 protein
  • G4.5 protein
  • GB11956 protein
  • LVNCX protein
  • MGC54019 protein
  • taz protein
  • Taz1 protein
  • wu:fb39f12 protein
  • zgc:91803 protein

Protein level used designations for Tafazzin Proteins (TAZ)

tafazzin , Tafazzin , protein G4.5 , Barth syndrome) , endocardial fibroelastosis 2 , tafazzin (cardiomyopathy, dilated 3A (X-linked) , tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome)

GENE ID SPECIES
100446947 Pongo abelii
321965 Danio rerio
379259 Xenopus laevis
515177 Bos taurus
549220 Xenopus (Silurana) tropicalis
550948 Apis mellifera
3513201 Aspergillus fumigatus Af293
5993687 Aspergillus oryzae RIB40
10911739 Trichinella spiralis
100137265 Papio anubis
100196028 Salmo salar
100328759 Oryctolagus cuniculus
100528715 Ictalurus punctatus
6901 Homo sapiens
66826 Mus musculus
363521 Rattus norvegicus
612975 Canis lupus familiaris
449590 Pan troglodytes
574297 Macaca mulatta
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