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anti-Talin 1 (TLN1) Antibodies

TLN1 encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. Additionally we are shipping Talin 1 Proteins (10) and Talin 1 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TLN1 7094 Q9Y490
TLN1 21894 P26039
TLN1 313494  
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Top anti-Talin 1 Antibodies at

Showing 10 out of 84 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to TLN1 on formalin-fixed para... TLN1 monoclonal antibody (M03), clone 1A11. Western Blot analysis of T... 100 μg Log in to see 9 Days
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Talin 1 antibody [C3], C-term detects TLN1 protein at cyto... WB Image Talin 1 antibody detects Talin 1 protein by western blot anal... 100 μL Log in to see 2 to 3 Days
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
Chicken Mouse Un-conjugated WB   0.1 mg Log in to see 6 to 8 Days
Chicken Mouse Un-conjugated WB   100 μg Log in to see 8 to 10 Days
Human Mouse Un-conjugated WB TLN1 monoclonal antibody (M06), clone 2E10. Western Blot analysis of T... 0.1 mg Log in to see 8 to 11 Days
Chicken Mouse Un-conjugated IP   100 μg Log in to see 8 to 10 Days
Human Mouse Un-conjugated IHC (p), ELISA, WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days

TLN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine) ,
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Rat (Rattus) ,
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Top referenced anti-Talin 1 Antibodies

  1. Cow (Bovine) Polyclonal TLN1 Primary Antibody for EIA, WB - ABIN453977 : Manevich, Grabovsky, Feigelson, Alon: Talin 1 and paxillin facilitate distinct steps in rapid VLA-4-mediated adhesion strengthening to vascular cell adhesion molecule 1. in The Journal of biological chemistry 2007 (PubMed)

  2. Human Monoclonal TLN1 Primary Antibody for IHC (p), ELISA - ABIN520958 : Lai, Hua, Tsai, Wan, Lin, Chen, Chiu, Chan, Tsai, Jinn-Chyuan Sheu: Talin-1 overexpression defines high risk for aggressive oral squamous cell carcinoma and promotes cancer metastasis. in The Journal of pathology 2011 (PubMed)

More Antibodies against Talin 1 Interaction Partners

Horse (Equine) Talin 1 (TLN1) interaction partners

  1. CD90 (Thy1 (show THY1 Antibodies)) is a novel interactor of talin 1 in effector cells of autoimmune equine uveitis.

Human Talin 1 (TLN1) interaction partners

  1. TLN1 significantly increases in refractory glioblastoma multiforme

  2. Applying correlative imaging to link live cell and fixed immunofluorescence data on a single cell basis, we related per cell talin-1 levels to per cell measures quantitatively defining an array of cellular properties.

  3. Disruption of the RIAM (show APBB1IP Antibodies)/lamellipodin (show RAPH1 Antibodies)-integrin-talin complex markedly impairs cell migration.

  4. Our data demonstrate that high expression of Talin-1 is associated with significantly poorer OS and poorer DMFS in NPC (show NPC1 Antibodies) and depletion of Talin-1 expression inhibited NPC (show NPC1 Antibodies) cell migration and invasion. Talin-1 may serve as novel prognostic biomarker in NPC (show NPC1 Antibodies).

  5. The activation of vinculin (show VCL Antibodies) by stretched talin induces a positive feedback that reinforces the actin-talin-vinculin (show VCL Antibodies) association.

  6. Data (including data from molecular dynamic simulations) suggest specific interactions between glycoprotein GPIIb (show ITGA2B Antibodies)/GPIIIa (show ITGB3 Antibodies) complex transmembrane/C-terminal domains and talin-1 in cell membrane environment during platelet activation.

  7. Data suggest that anionic lipids (such as phosphatidylinositol phosphates) play crucial role in localization of peripheral membrane proteins (such as TLN1, auxilin (show DNAJC6 Antibodies)-1, and PTEN (show PTEN Antibodies) [phosphatase and tensin homolog (show PTEN Antibodies)]). [review-like article]

  8. Low levels of Talin-1 expression are correlated with increased invasion and migration in liver cancer.

  9. Data indicate the role of vinculin (show VCL Antibodies) in inducing the talin mediated integrin activation.

  10. MMP-2 (show MMP2 Antibodies) regulates human platelet activation through hydrolysis of talin

Mouse (Murine) Talin 1 (TLN1) interaction partners

  1. Binding of vinculin (show VCL Antibodies) to the R1-R3 region of the talin rod is important for focal adhesion stability.

  2. Data indicate that talin mechanics are isoform specific so that expression of either talin-1 or talin-2 (show TLN2 Antibodies) modulates extracellular rigidity sensing.

  3. Conformational activation of talin by PREL-1 (show APBB1IP Antibodies) triggers integrin-mediated cell adhesion.

  4. Direct methylation of talin, a key regulatory molecule in cell migration, by Ezh2 disrupted the binding of talin to F-actin and thereby promoted the turnover of adhesion structures.

  5. reduction of talin-beta3 integrin (show ITGB3 Antibodies) binding affinity results in decelerated alphaIIbbeta3 integrin activation and protection from arterial thrombosis without pathological bleeding

  6. As talin engages F-actin, force exerted on the R2R3 helical bundles disrupts RIAM (show APBB1IP Antibodies) binding and exposes the vinculin (show VCL Antibodies) binding sites, which recruit vinculin (show VCL Antibodies) to stabilize the complex.

  7. Talin1 has unique expression versus talin 2 (show TLN2 Antibodies) in the heart and modifies the hypertrophic response to pressure overload.

  8. Talin1 and Rap1 are critical for resorptive function, and their selective inhibition in mature osteoclasts retards pathological bone loss.

  9. Talin binding to the membrane-proximal NPxY is crucial for connecting alpha5beta1 to the actin cytoskeleton.

  10. a novel proteolytic product of talin that is regulated by arginylation and a new role of talin in cadherin-dependent cell-cell adhesion.

Zebrafish Talin 1 (TLN1) interaction partners

  1. suggest that Tln1-mediated Itgbeta1b plays a crucial role in maintaining cardiac sarcomeric Z-disks and endothelial/endocardial cell integrity in zebrafish

Talin 1 (TLN1) Antigen Profile

Protein Summary

This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.

Gene names and symbols associated with anti-Talin 1 (TLN1) Antibodies

  • talin 1 (TLN1) antibody
  • talin 1 (tln1) antibody
  • Talin 1 (Bm1_56490) antibody
  • talin 1 (LOC100217512) antibody
  • talin 1 (Tln1) antibody
  • talin-1-like (LOC100856393) antibody
  • ILWEQ antibody
  • sb:cb854 antibody
  • talin-1 antibody
  • Tln antibody
  • TLN1 antibody
  • wu:fb05c02 antibody

Protein level used designations for anti-Talin 1 (TLN1) Antibodies

talin 1 , Talin 1 , Talin-1 , talin-1-like , talin-1

474759 Canis lupus familiaris
496216 Xenopus laevis
696298 Macaca mulatta
733752 Xenopus (Silurana) tropicalis
6106180 Brugia malayi
100055501 Equus caballus
100217512 Taeniopygia guttata
100380665 Salmo salar
100408584 Callithrix jacchus
100471856 Ailuropoda melanoleuca
7094 Homo sapiens
395194 Gallus gallus
21894 Mus musculus
313494 Rattus norvegicus
783470 Bos taurus
494453 Danio rerio
100856393 Canis lupus familiaris
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