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TLN1 Products

(Talin 1 (TLN1))
This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq, Feb 2009].

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Featured TLN1 Categories

TLN1 Antibodies

High quality antibodies with extensive validation data.

TLN1 ELISA Kits

Reliable ELISA kits for a wide range of species.

TLN1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TLN1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (1)
  • (5)
Cat. No. ABIN520958
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7442630
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN1683044
Quantity 100 μg
Datasheet Datasheet

Recommended TLN1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6959858
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970557
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959859
Quantity 96 tests
Datasheet Datasheet

Recommended TLN1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322852
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322854
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322856
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our TLN1 products

Shen, Zhang, Feng, Chen, Li, Iqbal, Liao, Zhao, Zhai: "iTRAQ-Based Proteomic Analysis Reveals Protein Profile in Plasma from Children with Autism." in: Proteomics. Clinical applications, Vol. 12, Issue 3, pp. e1700085, (2019) (PubMed).

Lagarrigue, Gingras, Paul, Valadez, Cuevas, Sun, Lopez-Ramirez, Goult, Shattil, Bergmeier, Ginsberg: "Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation." in: Blood advances, Vol. 2, Issue 18, pp. 2358-2368, (2018) (PubMed).

Xiong, Liang, Zhang, Wang, Huang, Peng, Wang, Xia: "Serum Proteome Alterations in Patients with Cognitive Impairment after Traumatic Brain Injury Revealed by iTRAQ-Based Quantitative Proteomics." in: BioMed research international, Vol. 2017, pp. 8572509, (2017) (PubMed).

Longo, Ioannidu, Scotto dAbusco, Superti, Misiano, Zanoni, Politi, Mazzola, Iosi, Mura, Scandurra: "Improving Osteoblast Response In Vitro by a Nanostructured Thin Film with Titanium Carbide and Titanium Oxides Clustered around Graphitic Carbon." in: PLoS ONE, Vol. 11, Issue 3, pp. e0152566, (2016) (PubMed).

Ding, Wang, Sui, Zhao, Xu, Li, Wang, Li, Zhou, Kong: "Claudin-7 indirectly regulates the integrin/FAK signaling pathway in human colon cancer tissue." in: Journal of human genetics, Vol. 61, Issue 8, pp. 711-20, (2016) (PubMed).

He, Meng, Yao, Jiang, Wu, Wu: "The essential role of inorganic substrate in the migration and osteoblastic differentiation of mesenchymal stem cells." in: Journal of the mechanical behavior of biomedical materials, Vol. 59, pp. 353-65, (2016) (PubMed).

Dingyu, Fanjie, Zhengzheng, Baosheng, Chao, Yi, Huiwen, Jun, Gang: "Regulation of Intracellular Structural Tension by Talin in the Axon Growth and Regeneration." in: Molecular neurobiology, (2015) (PubMed).

Manso, Li, Monkley, Cruz, Ong, Lao, Koshman, Gu, Peterson, Chen, Abel, Samarel, Critchley, Ross: "Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload." in: The Journal of biological chemistry, Vol. 288, Issue 6, pp. 4252-64, (2013) (PubMed).

Philippe, Léger, Desvaux, Walch: "Discs large 1 (Dlg1) scaffolding protein participates with clathrin and adaptator protein complex 1 (AP-1) in forming Weibel-Palade bodies of endothelial cells." in: The Journal of biological chemistry, Vol. 288, Issue 18, pp. 13046-56, (2013) (PubMed).

Thapa, Choi, Hedman, Tan, Anderson: "Phosphatidylinositol phosphate 5-kinase Iγi2 in association with Src controls anchorage-independent growth of tumor cells." in: The Journal of biological chemistry, Vol. 288, Issue 48, pp. 34707-18, (2013) (PubMed).

Synonyms and alternative names related to TLN1

talin 1 (TLN1), talin 1 (Tln1), talin 1 (tln1), talin 1 L homeolog (tln1.L), Talin 1 (Bm1_56490), talin-1 (LOC100380665), ILWEQ, sb:cb854, talin-1, TLN, Tln, tln, TLN1, wu:fb05c02

Protein level used designations for TLN1

  • talin-1
  • talin 1
  • Talin 1
  • Talin-1
  • talin-1-like
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