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Tenascin R (Restrictin, Janusin) Proteins (TNR)

Tenascin-R (TNR) is an extracellular matix protein expressed primarily in the central nervous system. Additionally we are shipping Tenascin R (Restrictin, Janusin) Antibodies (41) and Tenascin R (Restrictin, Janusin) Kits (23) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNR 7143 Q92752
TNR 21960 Q8BYI9
TNR 25567 Q05546
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Top Tenascin R (Restrictin, Janusin) Proteins at

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 69 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 69 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Rat GST tag,His tag   100 μg Log in to see 11 to 13 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

TNR Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Tenascin R (Restrictin, Janusin) (TNR) Interaction Partners

Human Tenascin R (Restrictin, Janusin) (TNR) interaction partners

  1. Two genes, TNR (and TNK2 (show TNK2 Proteins)), were found to have genetic variations linked to familial Parkinson's Disease.

  2. TnC (show TNC Proteins) and TnR play important roles in nervous and immune systems. [Review]

  3. citation presents comparison with human gene.

  4. results show that tenascin-R expression is tightly regulated in a spatiotemporal manner during brain development, especially cortical plate formation; its pattern of expression suggests a role for tenascin-R in corticogenesis

  5. KIAA0510, the 3'-untranslated region of the tenascin-R gene, and tenascin-R are overexpressed in pilocytic astrocytomas

  6. The researchers found evidence that the tenascin R gene is a potential susceptiblity or marker gene for IgA nephropathy.

  7. Tenascin R is expressed and glycosylated in neurons

  8. An extracellular matrix molecule TNR and its associated carbohydrate human natural killer cell glycan (HNK-1 (show B3GAT1 Proteins)) provide conditions beneficial for induction of long-term potentiation in the hippocampus.

Mouse (Murine) Tenascin R (Restrictin, Janusin) (TNR) interaction partners

  1. Tenascin-R promotes assembly of the extracellular matrix of perineuronal nets via clustering of aggrecan (show ACAN Proteins).

  2. Aggrecan (show ACAN Proteins), link protein (show HAPLN1 Proteins) and TN-R were identified to be essential for the neuroprotective properties of the perineuronal net.

  3. These findings indicate the importance of TNR in the regulation of hippocampal neurogenesis and suggest that TNR acts through distinct direct and indirect mechanisms during development and in the adult.

  4. TNR is expressed in a subset of astrocytes and contributes to glutamate (show GRIN1 Proteins) homeostasis by regulating astrocytic GLAST (show SLC1A3 Proteins) expression.

  5. Our results indicate that TNR modulates adult but not developmental neurogenesis in the olfactory bulb

  6. This study provided evidence that the tenascin-R modulates synaptogenesis and long-term synapse stability. The mutant neurons display reduced frequencies of mEPSCs and mIPSCs.

  7. Ablation of TNR modifies the extracellular matrix and leads to reorganization of the dentate gyrus with enhanced GABAergic innervation and altered plasticity, promoting working memory and reversal learning.

  8. TN-R appears to play an important role in the regulation of the number and architecture of perisomatic inhibitory synapses onto hippocampal pyramidal cells.

  9. the impact of TN-R deficiency on the living animal

  10. murine tenascin-R gene structure and functional characterisation of the promoter

Tenascin R (Restrictin, Janusin) (TNR) Protein Profile

Protein Summary

Tenascin-R (TNR) is an extracellular matix protein expressed primarily in the central nervous system. It is a member of the tenascin (TN) gene family, which includes at least 3 genes in mammals: TNC (or hexabrachion\; MIM 187380), TNX (TNXB\; MIM 600985), and TNR (Erickson, 1993

Gene names and symbols associated with TNR

  • tenascin R (TNR)
  • tenascin R (Tnr)
  • tenascin R (restrictin, janusin) (TNR)
  • J1-tenascin protein
  • J1NRM protein
  • janusin protein
  • restrictin protein
  • TN-R protein

Protein level used designations for TNR

janusin , restrictin , tenascin-R , neural recognition molecule J1-160/180 , TN-R , Tenascin-R (Restrictin janusin J1-160/180) , Tenascin-R (Restrictin, janusin, J1-160/180) , tenascin R (restrictin, janusin)

7143 Homo sapiens
21960 Mus musculus
25567 Rattus norvegicus
100347324 Oryctolagus cuniculus
100713399 Cavia porcellus
100520686 Sus scrofa
490334 Canis lupus familiaris
101117435 Ovis aries
396213 Gallus gallus
526409 Bos taurus
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