Tet Methylcytosine Dioxygenase 2 (TET2) ELISA Kits

The protein encoded by TET2 is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. Additionally we are shipping TET2 Antibodies (122) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human TET2 TET2 54790 Q6N021
TET2 214133 Q4JK59
Anti-Rat TET2 TET2 310859  
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Top TET2 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 5.86 pg/mL 23.44-1500 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details

More ELISA Kits for TET2 Interaction Partners

Human Tet Methylcytosine Dioxygenase 2 (TET2) interaction partners

  1. TET2 removes aberrant DNA methylation (show HELLS ELISA Kits) during oxidative stress through interaction with DNA methyltransferases in a "Yin-Yang" complex targeted to chromatin and enhanced by p300 (show EP300 ELISA Kits) mediated TET2 acetylation.

  2. we show that the TET2 expression and 5hmC abundance are significantly altered in the umbilical veins of GDM and preeclampsia.The alteration of TET expression, 5hmC levels and 5hmC-mediated transposon activity was further confirmed using established hypoxia cell culture model, which could be rescued by vitamin C, a known activator of TET proteins

  3. Because the DNA hypomethylation might be a result of TET dioxygenase activity, the study examined expression of TET1-3 enzymes and the level of their product, 5-hydroxymethylcytosine (5hmC), in a panel of histologically characterized seminomas and non-seminomatous germ cell tumors. The study found highly increased expression of TET1 dioxygenase in most seminomas and strong TET1 staining in seminoma cells.

  4. this study shows that Tet2 expression is increased in intratumoral myeloid cells in melanoma patients

  5. hypermethylation of the MEG3 (show FAM129B ELISA Kits) promoter in AML (show RUNX1 ELISA Kits) may result from decreased TET2 activity. These data provide insight into the molecular mechanisms underlying AML (show RUNX1 ELISA Kits) development and progression

  6. Our findings suggest that TET2 mutations have no prognosis impact on overall survival of patients with myelodysplastic syndromes

  7. ANRIL knockdown blocks the effects of TET2 on gastric cancer cell proliferation and colony formation.

  8. indicate that AID and TET2 share common effects on myeloid and erythroid lineage differentiation, however, their role is nonredundant in regulating HSC (show FUT1 ELISA Kits) self-renewal and in myeloid transformation.

  9. The prevalence of TET2 mutations in children with acute myeloid leukemia (show BCL11A ELISA Kits) (AML (show RUNX1 ELISA Kits)) compared with adults with AML (show RUNX1 ELISA Kits) was lower and less complex. Patients with polymorphism I1762V had an increased 10-year survival rate compared with patients without I1762V.

  10. Somatic mutations driving clonal hematopoiesis occur mainly in DNMT3A (show DNMT3A ELISA Kits) and TET2 and have no significant impact on hematological phenotypes. There is a familial predisposition to acquire TET2 mutation.

Mouse (Murine) Tet Methylcytosine Dioxygenase 2 (TET2) interaction partners

  1. in the absence of TET2, mast cell differentiation is under the control of compensatory mechanisms mediated by other TET family members, while proliferation is strictly dependent on TET2 expression.

  2. ablation of Tet2 in myeloid cells suppresses melanoma growth in vivo and shifted the immunosuppressive gene expression program in tumor-associated macrophages to a proinflammatory one

  3. These results support the hypothesis that somatic TET2 mutations in blood cells play a causal role in atherosclerosis.

  4. Loss of TET2 expression is associated with development of malignancy.

  5. confirm the transformation potential of DNMT3A (show DNMT3A ELISA Kits)(R882H) Tet2(-/-) progenitors and represent the first cooperative model in mice involving Tet2 inactivation driving lymphoid malignancies

  6. indicate that AID and TET2 share common effects on myeloid and erythroid lineage differentiation, however, their role is nonredundant in regulating HSC (show FUT1 ELISA Kits) self-renewal and in myeloid transformation.

  7. the results showed that low shear stress downregulated endothelial cell autophagy by impaired TET2 expression, which might contribute to the atherogenic process.

  8. Zfp281 interacts with Tet1, but not Tet2, and its direct transcriptional target, miR (show MLXIP ELISA Kits)-302/367, to negatively regulate Tet2 expression to establish and maintain primed pluripotency.

  9. tet2 activity in GnRH neurons has influence over the neuroendocrine control of male reproductive function

  10. this study shows that simultaneous deletion of Tet2 and Tet3 (show TET3 ELISA Kits) in mouse CD4 (show CD4 ELISA Kits)+CD8 (show CD8A ELISA Kits)+ double-positive thymocytes results in dysregulated development and proliferation of invariant natural killer T cells

TET2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TET2

  • tet methylcytosine dioxygenase 2 (TET2) antibody
  • tet methylcytosine dioxygenase 2 (Tet2) antibody
  • Ayu17-449 antibody
  • E130014J05Rik antibody
  • KIAA1546 antibody
  • MDS antibody
  • mKIAA1546 antibody
  • RGD1311625 antibody

Protein level used designations for TET2

methylcytosine dioxygenase TET2 , probable methylcytosine dioxygenase TET2 , tet oncogene family member 2 , tet oncogene 2

GENE ID SPECIES
54790 Homo sapiens
478499 Canis lupus familiaris
214133 Mus musculus
310859 Rattus norvegicus
422540 Gallus gallus
100521465 Sus scrofa
538481 Bos taurus
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