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anti-Transcobalamin II (TCN2) Antibodies

TCN2 encodes a member of the vitamin B12-binding protein family. Additionally we are shipping Transcobalamin II Kits (17) and Transcobalamin II Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TCN2 21452 O88968
TCN2 64365 Q9R0D6
TCN2 6948 P20062
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Top anti-Transcobalamin II Antibodies at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 16 Days
$163.90
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB Mouse Pancreas; WB Suggested Anti-Tcn2 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Mouse Pancreas; Tcn2 antibody - N-terminal region in Mouse Pancreas cells using Western Blot 50 μg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of Transcobalamin-2 staining in mouse brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated Western blot analysis of Transcobalamin-2 expression in MCF7 (A), A549 (B), mouse kidney (C), mouse lung (D) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged TCN2 is 1 ng/ml as a capture antibody. Western Blot analysis of TCN2 expression in transfected 293T cell line by TCN2 monoclonal antibody (M01), clone 2F4.Lane 1: TCN2 transfected lysate (Predicted MW: 47.5 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$430.00
Details
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 16 Days
$273.90
Details
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days
$379.50
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 8 to 10 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using TCN2 antibody. 200 μL Log in to see 8 to 9 Days
$588.50
Details

TCN2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Transcobalamin II Antibodies

  1. Mouse (Murine) Polyclonal TCN2 Primary Antibody for ELISA - ABIN2001335 : Seetharam, Li: Transcobalamin II and its cell surface receptor. in Vitamins and hormones 2000 (PubMed)

More Antibodies against Transcobalamin II Interaction Partners

Human Transcobalamin II (TCN2) interaction partners

  1. 4 patients with transcobalamin II deficiency were found to have novel mutations, of whom 2 had the same large deletion (homozygous c.1106+1516-1222+1231del). One had c.1107- 347_1222+981delin 364. Another had homozygous c.106C>T. (Q36X).

  2. There were no other associations between single -nucleotide polymorphisms and the efficacy of MTX (show MTX1 Antibodies) treatment. CONCLUSIONS: The MTHFR (show MTHFR Antibodies) 677CC and GGH (show GGH Antibodies) 401TT and CT genotypes were associated with a reduction in the number of MTX (show MTX1 Antibodies)-related adverse events.

  3. Report TCN2 mutations causing transcobalamin deficiency in an Indian patient.

  4. Although not significant when corrected for multiple testing, eight single nucleotide polymorphisms (SNPs) in two genes, transcobalamin II (TCN2) and the transcobalamin II-receptor (TCblR (show CD320 Antibodies)), were found to influence several clinical traits of cobalamin deficiency.

  5. In Asian populations, the investigated polymorphisms mapping at TCN2 and CBS (show CBS Antibodies) genes did not provide any evidence of association with cleft lip/cleftpalate.

  6. TCN2 776C --> G polymorphism is negatively associated with Alzheimer's type dementia, suggesting a protective role against the disease in subjects with the 5, 10-methylenetetrahydrofolate reductase (show MTHFR Antibodies) 1298AA genotype

  7. Transcobalamin II (TCN2 67A>G and TCN2 776C>G) and transcobalamin II receptor (TCblR (show CD320 Antibodies) 1104C>T) polymorphisms in Korean patients with idiopathic recurrent spontaneous abortion

  8. neither MTHFD (show MTHFD1 Antibodies) G1958A nor TC C776G polymorphisms are an independent risk factor for Down syndrome. However, the combined MTHFD (show MTHFD1 Antibodies)/MTHFR (show MTHFR Antibodies), TC/MTHFR (show MTHFR Antibodies) genotypes play a role in the risk of bearing a Down syndrome child in the Chinese population.

  9. Report TCN2 mutations causing transcobalamin deficiency in a family.

  10. Proliferating cancer cells express measurable levels of TCII and TCII-R.

Cow (Bovine) Transcobalamin II (TCN2) interaction partners

  1. study investigated crystallographically the beta-ligand exchange on Cbl bound to transcobalamin (TC) by crystallization of bovine holo-TC in the presence of either cyanide or sulfite

Transcobalamin II (TCN2) Antigen Profile

Protein Summary

This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with TCN2

  • transcobalamin 2 (Tcn2) antibody
  • transcobalamin II (TCN2) antibody
  • AW208754 antibody
  • D22S676 antibody
  • D22S750 antibody
  • II antibody
  • TC antibody
  • TC-2 antibody
  • TC2 antibody
  • TCII antibody
  • TC II antibody
  • Tcn-2 antibody
  • Tcn2p antibody

Protein level used designations for TCN2

TC II , TC-2 , TCII , transcobalamin II , transcobalamin-2 , macrocytic anemia , transcobalamin II; macrocytic anemia , vitamin B12-binding protein 2

GENE ID SPECIES
21452 Mus musculus
64365 Rattus norvegicus
6948 Homo sapiens
281518 Bos taurus
100171681 Pongo abelii
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