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TCN2 encodes a member of the vitamin B12-binding protein family. Additionally we are shipping Transcobalamin II Kits (16) and Transcobalamin II Proteins (12) and many more products for this protein.
Showing 10 out of 40 products:
Mouse (Murine) Polyclonal TCN2 Primary Antibody for ELISA - ABIN2001335
Seetharam, Li: Transcobalamin II and its cell surface receptor. in Vitamins and hormones 2000
In Asian populations, the investigated polymorphisms mapping at TCN2 and CBS (show CBS Antibodies) genes did not provide any evidence of association with cleft lip/cleftpalate.
TCN2 776C --> G polymorphism is negatively associated with Alzheimer's type dementia, suggesting a protective role against the disease in subjects with the 5, 10-methylenetetrahydrofolate reductase (show MTHFR Antibodies) 1298AA genotype
Transcobalamin II (TCN2 67A>G and TCN2 776C>G) and transcobalamin II receptor (TCblR (show CD320 Antibodies) 1104C>T) polymorphisms in Korean patients with idiopathic recurrent spontaneous abortion
neither MTHFD (show MTHFD1 Antibodies) G1958A nor TC C776G polymorphisms are an independent risk factor for Down syndrome. However, the combined MTHFD (show MTHFD1 Antibodies)/MTHFR (show MTHFR Antibodies), TC/MTHFR (show MTHFR Antibodies) genotypes play a role in the risk of bearing a Down syndrome child in the Chinese population.
Report TCN2 mutations causing transcobalamin deficiency in a family.
Proliferating cancer cells express measurable levels of TCII and TCII-R.
haplotype association analysis revealed a significant association between idiopathic pulmonary fibrosis and transcobalamin II gene polymorphisms
observation suggests that the missense variant Tc2. 776C>G influences both neurotoxicity and efficacy of methotrexate in patients with primary central nervous system lymphoma
preliminary results indicate that transcobalamin 2 gene polymorphisms can be a susceptibility factor for colorectal cancer
Three SNPs in transcobalamin II gene (G1196A, C776G and C1043T) are significantly associated with coronary artery disease in Indian population.
study investigated crystallographically the beta-ligand exchange on Cbl bound to transcobalamin (TC) by crystallization of bovine holo-TC in the presence of either cyanide or sulfite
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.
, transcobalamin II
, macrocytic anemia
, transcobalamin II; macrocytic anemia
, vitamin B12-binding protein 2