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TDP1 Antibodies

(Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA.
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) antibody anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) antibody anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) antibody [ABIN949469]

TDP1 Reactivity: Human IF, IP, WB Host: Rabbit Polyclonal unconjugated

anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (Center) antibody anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (Center) antibody anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (Center) antibody [ABIN2857076]

TDP1 Reactivity: Human ICC, IF, IHC (p), WB Host: Rabbit Polyclonal unconjugated

anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 4-215) antibody anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 4-215) antibody anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 4-215) antibody [ABIN5014489]

TDP1 Reactivity: Mouse ICC, IHC, WB Host: Rabbit Polyclonal unconjugated

TDP1 Antibodies by Grade

Find TDP1 Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

TDP1 Antibodies by Reactivity

Find TDP1 Antibodies for a variety of species such as anti-Human TDP1, anti-Mouse TDP1, anti-Rat TDP1. The species listed below are among those available. Click on a link to go to the corresponding products.

TDP1 Antibodies by Application

Find TDP1 Antibodies validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

TDP1 Antibodies by Host

Find TDP1 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

TDP1 Antibodies by Binding Specificity

Find TDP1 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

TDP1 Antibodies by Clonality

Find available monoclonal or polyclonal TDP1 Antibodies. Click on a link to go to the corresponding products.

TDP1 Antibodies by Clone

Find TDP1 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

TDP1 Antibodies by Conjugate

Find TDP1 Antibodies with a specific conjugate such as APC, FITC, PE. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular TDP1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (5)
  • collections(1)
Cat. No. ABIN565920
Quantity 50 μL
Reactivity Human
Application ELISA, WB
Validations
  • collections(2)
Cat. No. ABIN565921
Quantity 100 μg
Reactivity Human
Application IHC (p), ELISA, WB
Validations
  • collections(2)
Cat. No. ABIN1724362
Quantity 50 μL
Reactivity Human
Application ELISA, WB
Validations
  • collections(1)
Cat. No. ABIN2613485
Quantity 100 μg
Reactivity Human
Application ELISA, WB
Validations
  • collections(1)
Cat. No. ABIN934051
Quantity 100 μL
Reactivity Human, Mouse
Application WB
Validations
  • collections(1)
Cat. No. ABIN928939
Quantity 100 μL
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • collections(1)
Cat. No. ABIN2787112
Quantity 100 μL
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • collections(1)
Cat. No. ABIN2787113
Quantity 100 μL
Reactivity Human, Mouse
Application WB
Validations
  • collections(1)
Cat. No. ABIN1538086
Quantity 400 μL
Reactivity Human
Application WB
Validations
  • collections(1)
Cat. No. ABIN527662
Quantity 50 μL
Reactivity Guinea Pig, Horse, Human, Monkey, Mouse
Application WB
Validations
  • collections(1)
Cat. No. ABIN6746494
Quantity 100 μL
Reactivity Human
Application ELISA, IHC, IP, WB
Validations
Cat. No. ABIN7174129
Quantity 100 μL
Reactivity Human, Mouse, Rat
Application ELISA, IP, WB
Validations
Cat. No. ABIN7120443
Quantity 100 μg
Reactivity Human
Application EIA, RIA
Validations
Cat. No. ABIN5566203
Quantity 150 μg
Reactivity Human
Application FACS, ICC, IF, IHC
Validations
Cat. No. ABIN5566204
Quantity 150 μg

Latest Publications on our TDP1 Antibodies

Meisenberg, Gilbert, Chalmers, Haley, Gollins, Ward, El-Khamisy: "Clinical and cellular roles for TDP1 and TOP1 in modulating colorectal cancer response to irinotecan." in: Molecular cancer therapeutics, Vol. 14, Issue 2, pp. 575-85, (2015) (PubMed).

Das, Huang, Murai, Rehman, Amé, Sengupta, Das, Majumdar, Zhang, Biard, Majumder, Schreiber, Pommier: "PARP1-TDP1 coupling for the repair of topoisomerase I-induced DNA damage." in: Nucleic acids research, Vol. 42, Issue 7, pp. 4435-49, (2014) (PubMed).

Katyal, Lee, Nitiss, Downing, Li, Shimada, Zhao, Russell, Petrini, Nitiss, McKinnon: "Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes." in: Nature neuroscience, Vol. 17, Issue 6, pp. 813-21, (2014) (PubMed).

Perego, Cossa, Tinelli, Corna, Carenini, Gatti, De Cesare, Ciusani, Zunino, Luison, Canevari, Zaffaroni, Beretta: "Role of tyrosyl-DNA phosphodiesterase 1 and inter-players in regulation of tumor cell sensitivity to topoisomerase I inhibition." in: Biochemical pharmacology, Vol. 83, Issue 1, pp. 27-36, (2011) (PubMed).

Hawkins, Subler, Akopiants, Wiley, Taylor, Rice, Windle, Valerie, Povirk: "In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutation." in: DNA repair, Vol. 8, Issue 5, pp. 654-63, (2009) (PubMed).

Das, Antony, Gupta, Dexheimer, Redon, Garfield, Shiloh, Pommier: "Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA-PK." in: The EMBO journal, Vol. 28, Issue 23, pp. 3667-80, (2009) (PubMed).

Katyal, el-Khamisy, Russell, Li, Ju, Caldecott, McKinnon: "TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo." in: The EMBO journal, Vol. 26, Issue 22, pp. 4720-31, (2007) (PubMed).

Aliases for TDP1 Antibodies

tyrosyl-DNA phosphodiesterase 1 (TDP1) Antibodies
tyrosyl-DNA Phosphodiesterase (Tdp1) (Tc00.1047053511191.10) Antibodies
tyrosyl-DNA phosphodiesterase 1 (Tdp1) Antibodies
tyrosyl-DNA phosphodiesterase 1 L homeolog (tdp1.L) Antibodies
tyrosyl-DNA phosphodiesterase 1 (tdp1) Antibodies
tyrosyl-DNA phosphodiesterase-like protein (TDP1) Antibodies
tyrosyl-DNA phosphodiesterase 1 (PTRG_11198) Antibodies
tyrosyl-DNA phosphodiesterase 1 (MCYG_02121) Antibodies
tyrosyl-DNA phosphodiesterase 1 (MGYG_03035) Antibodies
2810481F14Rik Antibodies
4921509N21Rik Antibodies
AI838772 Antibodies
AW493413 Antibodies
E430034L06Rik Antibodies
F8M21.60 Antibodies
F8M21_60 Antibodies
MGC83708 Antibodies
MLZ-501 Antibodies
SCAN1 Antibodies
tdp1 Antibodies
TDP1 Antibodies
tyrosyl-DNA phosphodiesterase 1 Antibodies
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