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Transcription Factor A, Mitochondrial (TFAM) ELISA Kits

TFAM encodes a key mitochondrial transcription factor containing two high mobility group motifs. Additionally we are shipping TFAM Antibodies (113) and TFAM Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TFAM 7019 Q00059
TFAM 21780 P40630
TFAM 83474 Q91ZW1
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Top TFAM ELISA Kits at antibodies-online.com

Showing 3 out of 7 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.124 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details
Mouse 0.107 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
$757.89
Details
Rat 5.8 pg/ml 23.5-1500 pg/mL   96 Tests Log in to see 11 to 13 Days
$910.56
Details

More ELISA Kits for TFAM Interaction Partners

Human Transcription Factor A, Mitochondrial (TFAM) interaction partners

  1. Results showed that TFAM formed oligomers in mitochondria by in situ chemical cross-linking and suggested the importance of the dimerization of TFAM molecules in the distribution of mtDNA in cells.

  2. Report failed upregulation of TFAM protein and mitochondrial DNA in oxidatively deficient fibers in skeletal muscle of chronic obstructive pulmonary disease patients.

  3. Data show that mtTFA proteins are highly expressed in cancer and drug-resistant cells compared to normal cells, and the mtTFA expression is upregulated by signals of oxidative and DNA damage stress in cancer cells. [review]

  4. TFAM overexpression suppressed mitoROS and their upregulation in rat cardiomyocytes.

  5. TFAM dimerization enhances mitochondrial DNA compaction by promoting looping of the DNA.

  6. The combination of strong mtTFA expression and a high survivin (show BIRC5 ELISA Kits) index may predict a poor prognosis in patients with pancreatic ductal adenocarcinoma

  7. expression of PGC1alpha and TFAM varies between ovarian carcinoma subtypes; clear-cell carcinoma consists of undetectability of PGC1alpha/TFAM, and low ERalpha (show ESR1 ELISA Kits)/Ki-67 (show MKI67 ELISA Kits). high-grade serous carcinomas had a converse state of PGC1alpha/TFAM, ERalpha (show ESR1 ELISA Kits) positivity and high Ki-67 (show MKI67 ELISA Kits) index

  8. Methylation of TFAM promoters changed 2 days after gastric bypass.

  9. These data disclose a novel mechanism by which ERK1/2 (show MAPK1/3 ELISA Kits) regulates mitochondrial function through direct phosphorylation of TFAM.

  10. Data suggest that miitochondrial transcription factor A (show GTF3A ELISA Kits) (mtTFA) may be a novel target for the treatment of pancreatic ductal adenocarcinoma (PDAC).

Pig (Porcine) Transcription Factor A, Mitochondrial (TFAM) interaction partners

  1. TFAM may exert a critical role in porcine gametogenesis and preimplantation embryo development.

Cow (Bovine) Transcription Factor A, Mitochondrial (TFAM) interaction partners

  1. Our results suggest that TFAM plays an important role in lipid metabolism and may be a strong candidate gene for obesity in mammals.

  2. de novo mtTFA expression associated with mitochondrial biogenesis activation & high levels of nuclear respiratory factor-1 (show NRF1 ELISA Kits) mRNA from oocyte stage onwards argue for essential function of these factors during the first steps of bovine embryogenesis.

Mouse (Murine) Transcription Factor A, Mitochondrial (TFAM) interaction partners

  1. TFAM binds to RNA-containing 4-way junctions but does not bind appreciably to RNA hairpins, internal loops, or linear RNA:DNA hybrids.

  2. Data show that mitochondrial transcription factor A (TFAM) packages single mitochondrial DNA (mtDNA) molecules.

  3. There was upregulation of mtDNA and TFAM in 6-wk diabetic mice, suggesting that TFAM activation could be a therapeutic strategy to treat peripheral neuropathy.

  4. This study demonistrated that Tfam gene inactive patkinsin disease cause dopamine loss and circadian rhythm disorder.

  5. Mitochondrial transcription factor A, an endogenous danger signal, promotes TNFalpha (show TNF ELISA Kits) release via RAGE (show AGER ELISA Kits)- and TLR9 (show TLR9 ELISA Kits)-responsive plasmacytoid dendritic cells.

  6. overexpression of TFAM can restore mitochondrial function to normal levels in NYGGF4 (show PID1 ELISA Kits)-overexpressing adipocytes

  7. Acute exercise induces tumour suppressor protein p53 (show TP53 ELISA Kits) translocation to the mitochondria and promotes a p53 (show TP53 ELISA Kits)-Tfam-mitochondrial DNA complex in skeletal muscle.

  8. Data indicate that TFAM-deficient keratinocytes failed to generate mitochondria-derived reactive oxygen species, and prevented the transmission of Notch (show NOTCH1 ELISA Kits) and beta-catenin (show CTNNB1 ELISA Kits) signals for epidermal differentiation and hair follicle development.

  9. The reduction of mitochondrial transcription factor A (TFAM) in adipose tissue increases mitochondria oxidation capacity due to complex I deficiency and greater uncoupling.

  10. Data suggest that microRNA 494 regulates mitochondrial biogenesis by down-regulating mtTFA (mitochondrial transcription factor A) and Foxj3 (forkhead box J3 protein) during myocyte differentiation and skeletal muscle adaptation to physical exercise.

TFAM Antigen Profile

Antigen Summary

This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with TFAM

  • transcription factor A, mitochondrial (TFAM) antibody
  • transcription factor A, mitochondrial (tfam) antibody
  • transcription factor A, mitochondrial (Tfam) antibody
  • AI661103 antibody
  • Hmgts antibody
  • MGC153358 antibody
  • MTTF1 antibody
  • Mttfa antibody
  • mttfa-A antibody
  • TCF6 antibody
  • TCF6L1 antibody
  • TCF6L2 antibody
  • TCF6L3 antibody
  • tsHMG antibody
  • xl-mtTFA antibody
  • zgc:153358 antibody

Protein level used designations for TFAM

transcription factor A, mitochondrial , HMG box mitochondrial transcription factor , mitochondrial transcription factor 1 , mitochondrial transcription factor A , transcription factor 6 , transcription factor 6-like 1 , transcription factor 6-like 2 (mitochondrial transcription factor) , transcription factor 6-like 3 , mtTFA , transcription factor 6-like 2 , TS-HMG , testis-specific HMG-box protein m-tsHMG , testis-specific high mobility group protein

GENE ID SPECIES
373888 Gallus gallus
394385 Xenopus laevis
571106 Danio rerio
7019 Homo sapiens
488989 Canis lupus familiaris
397279 Sus scrofa
510059 Bos taurus
21780 Mus musculus
83474 Rattus norvegicus
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