Transcription Factor E3 (TFE3) ELISA Kits

The microphthalmia transcription factor/transcription factor E (MITF-TFE) family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors includes four family members: MITF, TFE3, TFEB and TFEC. Additionally we are shipping TFE3 Antibodies (99) and TFE3 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TFE3 7030 P19532
Anti-Rat TFE3 TFE3 317376  
TFE3 209446 Q64092
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Top TFE3 ELISA Kits at antibodies-online.com

Showing 2 out of 6 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.118 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 13 to 16 Days
$589.47
Details
Human
  96 Tests Log in to see 6 Days
$610.39
Details

More ELISA Kits for TFE3 Interaction Partners

Human Transcription Factor E3 (TFE3) interaction partners

  1. we analyze 60 Xp11 translocation cancers by fluorescence in situ hybridization using custom bacterial artificial chromosome probes to establish their TFE3 fusion gene partner

  2. These results show that ASPL (show ASPSCR1 ELISA Kits)-TFE3 regulates cell cycle progression and induces cellular senescence by up-regulating p21 (show CDKN1A ELISA Kits) expression.

  3. RBM10-TFE3 is a recurrent gene fusion in Xp11 translocation renal cell carcinoma.

  4. Case Report: melanotic PEComa of the sinonasal mucosa with NONO (show NONO ELISA Kits)-TFE3 fusion.

  5. Xp11 translocation renal cell carcinomas with RBM10 (show RBM10 ELISA Kits)-TFE3 gene fusion demonstrating melanotic features and overlapping morphology with t(6;11) RCC (show XRCC1 ELISA Kits).

  6. The essential parts of the Golgi stress response from the perspective of the organelle autoregulation. The pathways of the mammalian Golgi stress response have been identified, specifically the TFE3 pathway.

  7. Female patients with Xp11.2 renal cell carcinoma in adults exhibit a high incidence compared to male, but not in children. Comparable clinical characteristics including incidence of distant and lymphatic metastases, tumor stage and prognosis is presented between male and female as well as between children and adults

  8. RBM10 (show RBM10 ELISA Kits)-TFE3 fusion variant (from chromosome X paracentric inversion), therefore, appears to be a recurrent molecular event in Xp11.2 RCCs. RBM10 (show RBM10 ELISA Kits)-TFE3 fusion should be added in the list of screened fusion transcripts in targeted molecular diagnostic multiplex RT-PCR

  9. The recently identified group of Xp11.2 translocation/TFE gene fusion renal cell carcinomas (Xp11.2/TFE RCC) affect approximately 15 % of patients under 45 years old with renal cell carcinoma.

  10. Akt (show AKT1 ELISA Kits) modulates nuclear translocation of TFE3.

Mouse (Murine) Transcription Factor E3 (TFE3) interaction partners

  1. Tfe3 overexpression in HSPCs impaired long-term hematopoietic reconstitution in vivo, recapitulating the Flcn (show FLCN ELISA Kits) KO phenotype, and supporting the notion that abnormal activation of Tfe3 contributes to the Flcn (show FLCN ELISA Kits) KO phenotype. Flcn (show FLCN ELISA Kits) KO mice develop an acute histiocytic hyperplasia in multiple organs, suggesting a novel function for Flcn (show FLCN ELISA Kits) in macrophage development

  2. TFEB and TFE3 are novel components of the integrated stress response

  3. Tfe3 is a critical transcription factor that regulates Pgc-1alpha (show PPARGC1A ELISA Kits) gene expression in myotubes

  4. A conditional expression in mice of the fusion gene ASPSCR1 (show ASPSCR1 ELISA Kits)-TFE3 from human alveolar soft part sarcoma (ASPS (show DARS ELISA Kits)) generated a model that recapitulates the human tumor histologically and by expression profile.

  5. Data from transgenic mice suggest Tfe3 controls lipid metabolism in adipose tissue (white, WAT; brown, BAT (show BAAT ELISA Kits)); TFE3 appears to be regulated by diet; up-regulation of TFE3 may inhibit expression of lipolysis genes in WAT and thermogenesis genes in BAT (show BAAT ELISA Kits).

  6. These findings indicated that TFE3 has a regulatory role in myoblast differentiation, and that transcriptional suppression of myogenin (show MYOG ELISA Kits) expression may be part of the mechanism of action.

  7. Machinery regulating exit of embryonic stem cells from pluripotency is ill defined; Flcn (show FLCN ELISA Kits) with its interaction partners Fnip1 (show FNIP1 ELISA Kits) and Fnip2 drives differentiation by restricting nuclear localization and activity of the bHLH transcription factor Tfe3.

  8. TFE3 and Galpha (show SUCLG1 ELISA Kits)(16) are up-regulated under pathologic conditions and are involved in a novel mechanism of transcriptional regulation via the relocalization and activation of Galpha (show SUCLG1 ELISA Kits)(16).

  9. FLCN (show FLCN ELISA Kits) tumor suppressor gene inactivation induces TFE3 transcriptional activity by increasing its nuclear localization

  10. TFE3 and TFEB regulate E-cadherin (show CDH1 ELISA Kits) and WT1 (show WT1 ELISA Kits) expression

TFE3 Antigen Profile

Antigen Summary

The microphthalmia transcription factor/transcription factor E (MITF-TFE) family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors includes four family members: MITF, TFE3, TFEB and TFEC. The TEF3 protein encoded by this gene activates transcription through binding to the muE3 motif of the immunoglobulin heavy-chain enhancer. The TFEC protein forms heterodimers with the TEF3 protein and inhibits TFE3-dependent transcription activation. The TEF3 protein interacts with transcription regulators such as E2F3, SMAD3, and LEF-1, and is involved in TGF-beta-induced transcription, playing important roles in cell growth, proliferation, and osteoclast and macrophage differentiation. The TFE3 protein also activates hepatic IRS-2 gene, and induces hexokinase II (HK2) and insulin-induced gene 1 (INSIG1)\; it participates in insulin signaling and could be a therapeutic target for diabetes. This gene is also involved in chromosomal translocations, resulting in different fusion gene products in papillary renal cell carcinomas and alveolar soft part sarcomas, such as PRCC-TFE3, RCC17-TFE3, PSF-TFE3, NonO (p54nrb)-TFE3 and ASPL-TFE3.

Gene names and symbols associated with TFE3

  • transcription factor binding to IGHM enhancer 3 (TFE3) antibody
  • transcription factor binding to IGHM enhancer 3 (Tfe3) antibody
  • transcription factor binding to IGHM enhancer 3 (tfe3) antibody
  • transcription factor E3 (Tfe3) antibody
  • bHLHe33 antibody
  • F830016E06Rik antibody
  • RCCP2 antibody
  • RCCX1 antibody
  • RGD1559642 antibody
  • Tcfe3 antibody
  • Tfe-3 antibody
  • TFEA antibody

Protein level used designations for TFE3

class E basic helix-loop-helix protein 33 , transcription factor E family, member A , transcription factor E3 , transcription factor for IgH enhancer , transcription factor for immunoglobulin heavy-chain enhancer 3

GENE ID SPECIES
7030 Homo sapiens
491872 Canis lupus familiaris
520800 Bos taurus
317376 Rattus norvegicus
495043 Xenopus laevis
209446 Mus musculus
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