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Transthyretin Proteins (TTR)

TTR encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Additionally we are shipping Transthyretin Antibodies (371) and Transthyretin Kits (82) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TTR 7276 P02766
TTR 22139 P07309
TTR 24856 P02767
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Top Transthyretin Proteins at

Showing 10 out of 76 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 2 to 3 Days
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 7 to 8 Days
HOST_Escherichia coli (E. coli) Pig His tag,T7 tag 100 μg Log in to see 11 to 13 Days
Yeast Mouse His tag Transthyretin (TTR) (AA 21-147) protein (His tag) expressed in E. coli 1 mg Log in to see 56 to 66 Days
Yeast Macaca fascicularis His tag Transthyretin (TTR) (AA 21-147) protein (His tag) expressed in mammalien cells 1 mg Log in to see 56 to 66 Days
HOST_Mammalian Cells Human His tag   50 μg Log in to see 5 Days
HOST_Escherichia coli (E. coli) Guinea Pig His tag,T7 tag 100 μg Log in to see 11 to 13 Days

TTR Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , ,
Mouse (Murine) ,

Rat (Rattus) ,

Top referenced Transthyretin Proteins

  1. Human TTR Protein expressed in Human Cells - ABIN2005037 : Herbert, Wilcox, Pham, Fremeau, Zeviani, Dwork, Soprano, Makover, Goodman, Zimmerman: Transthyretin: a choroid plexus-specific transport protein in human brain. The 1986 S. Weir Mitchell award. in Neurology 1986 (PubMed)
    Show all 5 references for ABIN2005037

  2. Human TTR Protein expressed in HEK-293 Cells - ABIN2181876 : Getz, Kennedy, Mangini: Transthyretin localization in cultured and native human retinal pigment epithelium. in Experimental eye research 1999 (PubMed)
    Show all 5 references for ABIN2181876

  3. Human TTR Protein expressed in Escherichia coli (E. coli) - ABIN666931 : Ando: [Transthyretin: it's miracle function and pathogenesis]. in Rinsho byori. The Japanese journal of clinical pathology 2009 (PubMed)
    Show all 2 references for ABIN666931

More Proteins for Transthyretin (TTR) Interaction Partners

Human Transthyretin (TTR) interaction partners

  1. illustrates the diversity of symptoms encountered in homozygote ATTR V30M patients

  2. Data suggest that well-structured AB loop regions of TTR in native/homotetrameric/stable state become dissociated/disordered/unfolded at low pH; during refolding, structural perturbations in AB loop appear and facilitate misfolding and amyloid formation.

  3. Study elucidated alterations in TTR, APP (show APP Proteins) and the global gene expression profile in the frontal cortex between idiopathic normal pressure hydrocephalus patients and nondemented control brain

  4. Quantitative analysis of post-translational modifications in human serum transthyretin associated with familial amyloidotic polyneuropathy by targeted LC-MS and intact protein MS.

  5. Large differences in survival were observed in hereditary transthyretin amyloidosis patients with TTR mutations other than Val30Met.

  6. Ile107Val and LateMet30 TTR mutations are associated with the most debilitating and severe familial amyloid polyneuropathy, with rapid onset of tetraparesis and shorter median survival.

  7. study reports a novel TTR variant(TTR Asp38Tyr mutation) in 2 Brazilian sisters who developed a late onset neuropathy; new mutation calls attention to the diversity found in TTR familial amyloid polyneuropathy

  8. The structures of TTR in complex with three natural polyphenols (pterostilbene, quercetin and apigenin) have been determined.

  9. beta-strands F and H as necessary for TTR aggregation.

  10. Given the high conservation of TTR structure, function and tissue specificity and timing of gene expression, this implies that TTR has a fundamental role, during development and in the adult.

Mouse (Murine) Transthyretin (TTR) interaction partners

  1. provide evidence of a new role of Transthyretin as a transcription inducer of insulin (show INS Proteins)-like growth factor receptor (show RYK Proteins) I in central nervous system, unveiling a new role in neuroprotection

  2. data also indicate that it is unlikely that the behaviors seen in Ttr(-/-) mice are related to its function

  3. Native transthyretin inhibits all preeclampsia-like features in the humanized mouse model.

  4. Transthyretin silencing (TTRkd) significantly reduced myogenin (show MYOG Proteins) expression.

  5. Amyloid fibrils formed by a mutant form of TTR, A25T, activate microglia, leading to the secretion of tumor necrosis factor-alpha (TNF-alpha (show TNF Proteins)), interleukin-6 (IL-6 (show IL6 Proteins)) and nitric oxide.

  6. Hsf-1 (show HSF1 Proteins) affects podocyte markers NPHS1 (show NPHS1 Proteins), NPHS2 and WT1 (show WT1 Proteins) in a transgenic mouse model of TTRVal30Met-related amyloidosis.

  7. Fibroblasts endocytose and degrade transthyretin aggregates in transthyretin-related amyloidosis.

  8. Increased degradation of 14-3-3zeta (show YWHAZ Proteins) in lysosomes in the absence of TTR, increasing autophagy.

  9. our data demonstrate that the increased expression of Ttr in ob/ob mice does not cause (but rather attenuates) their phenotypic abnormalities.

  10. TTR has an important and nonredundant role in influencing the development of several organs.

Pig (Porcine) Transthyretin (TTR) interaction partners

  1. The rank order potency of the chemicals tested for the displacement of [125I]TIP from TTR was TIP > ioxynil > pentachlorophenol, T4, and retinoic acid > tetrabromobisphenol A, diethylstilbestrol, and T3.

  2. This study suggested closer links between the release of haptoglobin (show HP Proteins), Pig-MAP and monocytes compared to the release of AGP, SAA (show SAA1 Proteins) and transthyretin.

Xenopus laevis Transthyretin (TTR) interaction partners

  1. Study determined the genomic structure of the Xenopus laevis TTR gene including 5'-flanking regions, and examined TTR expression patterns in several tissues; coding regions of xTTR gene was separated into 4 exons by 3 introns and these numbers were in agreement with those determined for the human, mouse, and rat genes

Transthyretin (TTR) Protein Profile

Protein Summary

This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein\; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported\; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.

Gene names and symbols associated with Transthyretin Proteins (TTR)

  • transthyretin (prealbumin, amyloidosis type I) (ttr)
  • transthyretin (TTR)
  • transthyretin (vpb38)
  • transthyretin (Mrad2831_1253)
  • Transthyretin (Caci_4246)
  • transthyretin (prealbumin, amyloidosis type 1) (ttr)
  • transthyretin (LOC100226992)
  • transthyretin (Ttr)
  • transthyretin (LOC100347317)
  • transthyretin (ttr)
  • AA408768 protein
  • AI787086 protein
  • CTS protein
  • CTS1 protein
  • D17860 protein
  • HsT2651 protein
  • LOC100226992 protein
  • Lr1 protein
  • PALB protein
  • Prealbumin protein
  • Tbpa protein
  • TTR protein
  • xTTR protein
  • zgc:103583 protein

Protein level used designations for Transthyretin Proteins (TTR)

transthyretin , transthyretin (prealbumin, amyloidosis type I) , Transthyretin , transthyretin (prealbumin, amyloidosis type 1) , ATTR , carpal tunnel syndrome 1 , prealbumin, amyloidosis type I , thyroxine-binding prealbumin , TBPA , prealbumin

449556 Danio rerio
705943 Macaca mulatta
5383938 Vibrio vulnificus
6137271 Methylobacterium radiotolerans JCM 2831
8335600 Catenulispora acidiphila DSM 44928
100101780 Xenopus (Silurana) tropicalis
100226992 Taeniopygia guttata
7276 Homo sapiens
22139 Mus musculus
24856 Rattus norvegicus
396277 Gallus gallus
280948 Bos taurus
493188 Pan troglodytes
443389 Ovis aries
100347317 Oryctolagus cuniculus
100735950 Cavia porcellus
397419 Sus scrofa
480167 Canis lupus familiaris
397787 Xenopus laevis
100174094 Pongo abelii
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