Zinc Finger Protein, X-Linked Proteins (ZFX)

ZFX on the X chromosome is structurally similar to a related gene on the Y chromosome. Additionally we are shipping ZFX Antibodies (34) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse ZFX ZFX 22764 P17012
Rat ZFX ZFX 367832  
ZFX 7543 P17010
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Top ZFX Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
Yeast Wild boar His tag   1 mg Log in to see 60 to 71 Days

ZFX Proteins by Origin and Source

Origin Expressed in Conjugate

More Proteins for Zinc Finger Protein, X-Linked (ZFX) Interaction Partners

Mouse (Murine) Zinc Finger Protein, X-Linked (ZFX) interaction partners

  1. Zfx is a common cell-intrinsic regulator of diverse Hedgehog (show SHH Proteins)-induced tumors.

  2. Zfx, a transcription factor that controls hematopoietic stem cell self-renewal, controls the initiation and maintenance of acute myeloid leukemia (show BCL11A Proteins).

  3. These studies identify Zfx as a shared transcriptional regulator of embryonic stem cells and hematopoietic stem cells, suggesting a common genetic basis of self-renewal in embryonic and adult SC.

  4. Zfx restrains the stress response and couples antigen receptor signaling to cell expansion and maintenance during B-cell development and peripheral homeostasis

Human Zinc Finger Protein, X-Linked (ZFX) interaction partners

  1. colon cancer-associated transcript-1 knockdown inhibits proliferation and invasion of laryngeal squamous cell cancer cells through enhancing zinc finger protein, X-linked by sponging microRNA-218, elucidating a novel colon cancer-associated transcript-1-microRNA-218-zinc finger protein, X-linked regulatory axis in laryngeal squamous cell cancer and providing a promising therapeutic target for laryngeal cancer

  2. EZH2 and ZFX genes do not seem to have an impact on the onset of most parathyroid tumours, both benign and malignant, though further studies on larger cohorts of different ethnicity are needed.

  3. Zinc finger and X-linked factor ZFX transactivates the SET transcript 2 promoter through binding to a site closely located to the transcription start site.

  4. ZFX is over-expressed in HCC (show FAM126A Proteins) cells, and correlates with stem cell-like features and pleiotropic characteristics

  5. miR (show MLXIP Proteins)-144 has been demonstrated to act as a tumour suppressor in hepatocellular carcinoma (HCC (show FAM126A Proteins)) cell growth and motility by directly targeting ZFX, which implicates its potential applications in the development of HCC (show FAM126A Proteins) treatment

  6. demonstrated that ZFX is aberrantly expressed in multiple human leukemic cells and it modulates the growth and drug response of leukemic cells partially via B4GALT1, which suggests that ZFX is a new regulator of leukemic cells and warrants intensive investigations on this 'stemness' regulator in these deadly diseases

  7. ZFX is a novel oncogene (show RAB1A Proteins) promoting cell proliferation and inducing imatinib resistance via PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins) signaling pathway

  8. Zinc finger protein x-linked contributes to patient prognosis, and regulates cell proliferation and apoptosis in human laryngeal squamous cell carcinoma.

  9. ZFX expression may have a role in poor prognosis of renal cell carcinoma (show MOK Proteins) patients

  10. Nasopharyngeal carcinoma patients with high ZFX expression had lower 5-year overall survival rates, progression-free survival rates, loco-regional relapse-free survival rates and distant metastasis-free survival rates than those with low ZFX expression

Cow (Bovine) Zinc Finger Protein, X-Linked (ZFX) interaction partners

  1. ZFX transcripts were noted in all pre-compaction stage embryos and in female and male blastocysts; the expression of ZFX was significantly higher in female than in male blastocysts

ZFX Protein Profile

Protein Summary

This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined.

Gene names and symbols associated with ZFX

  • zinc finger protein X-linked (Zfx)
  • zinc finger protein, X-linked (zfx)
  • zinc finger protein, X-linked (ZFX)
  • RGD1562664 protein
  • xzfy-1 protein
  • Zfx5 protein
  • Zfx5,6 protein
  • Zfx6 protein
  • zfy1 protein
  • ZNF926 protein

Protein level used designations for ZFX

X-linked zinc finger protein , zinc finger X-chromosomal protein , zinc finger protein X-linked 5 , zinc finger protein X-linked 6 , ZFY-1 , zinc finger Y-chromosomal protein 1 , zinc finger protein 1, Y linked , zinc finger protein X-linked , Zinc finger X-chromosomal protein , zinc finger protein ZFX

22764 Mus musculus
367832 Rattus norvegicus
397971 Xenopus laevis
7543 Homo sapiens
280961 Bos taurus
397294 Sus scrofa
491778 Canis lupus familiaris
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