ZFX Products
(Zinc Finger Protein, X-Linked (ZFX))
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This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2010].
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Featured ZFX Categories
ZFX Antibodies
High quality antibodies with extensive validation data.
ZFX Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ZFX Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7176659
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN657487
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (1)
Cat. No.
ABIN7271539
Quantity
100 μL
Datasheet
Datasheet
Recommended ZFX Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3075706
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ZFX products
: "ZFX modulates the growth of human leukemic cells via B4GALT1." in: Acta biochimica et biophysica Sinica, Vol. 48, Issue 12, pp. 1120-1127, (2016) (PubMed).: "Dysregulation of zinc finger protein, X-linked (ZFX) impairs cell proliferation and induces apoptosis in human oral squamous cell carcinorma." in: Tumour biology, Vol. 36, Issue 8, pp. 6103-12, (2015) (PubMed).
: "Overexpression of ZFX and its involvement in squamous cell carcinoma of the tongue." in: Oncology reports, Vol. 33, Issue 1, pp. 141-8, (2014) (PubMed).
: "Roles of Mir-144-ZFX pathway in growth regulation of non-small-cell lung cancer." in: PLoS ONE, Vol. 8, Issue 9, pp. e74175, (2013) (PubMed).
: "Knockdown of zinc finger protein X-linked inhibits prostate cancer cell proliferation and induces apoptosis by activating caspase-3 and caspase-9." in: Cancer gene therapy, Vol. 19, Issue 10, pp. 684-9, (2012) (PubMed).
: "[A comparison of clinical outcomes between HLA allele matched and 1 - 2 alleles mismatched unrelated allogeneic bone marrow transplantations]." in: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, Vol. 25, Issue 2, pp. 74-7, (2004) (PubMed).
Synonyms and alternative names related to ZFX
zinc finger protein X-linked (Zfx), zinc finger protein, X-linked S homeolog (zfx.S), zinc finger protein, X-linked (ZFX), RGD1562664, xzfy-1, Zfx5, Zfx5,6, Zfx6, zfy1, ZNF926Protein level used designations for ZFX
- X-linked zinc finger protein
- zinc finger X-chromosomal protein
- zinc finger protein X-linked 5
- zinc finger protein X-linked 6
- ZFY-1
- zinc finger Y-chromosomal protein 1
- zinc finger protein 1, Y linked
- zinc finger protein X-linked
- Zinc finger X-chromosomal protein
- zinc finger protein ZFX
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