anti-delta-Like 1 Homolog (Drosophila) (DLK1) Antibodies

DLK1 encodes a transmembrane protein containing six epidermal growth factor repeats. Additionally we are shipping DLK1 Proteins (20) and DLK1 Kits (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DLK1 8788 P80370
DLK1 13386 Q09163
DLK1 114587  
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Top anti-DLK1 Antibodies at antibodies-online.com

Showing 10 out of 208 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rat Un-conjugated IHC (fro), FACS, IHC (p) 0.1 mg Log in to see 6 to 8 Days
$368.50
Details
Mouse Rat PE FACS 50 Tests Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated CyTOF, FACS, ICC, WB Detection of Pref-1/DLK1/FA1 in HepG2 Human Cell Line by Flow Cytometry. HepG2 human hepatocellular carcinoma cell line was stained with Mouse Anti-Human Pref-1/DLK1/FA1 Monoclonal Antibody. 100 μg Log in to see 8 to 9 Days
$294.00
Details
Mouse Rat FITC FACS 100 μL Log in to see 11 to 13 Days
$427.35
Details
Mouse Rat Un-conjugated ELISA, WB Western blot analysis using anti-DLK1 (mouse), mAb (PF105B)  at 1:2'000 dilution. A) 1: Mouse DLK1 Fc-protein. 2: Human DLK1 Fc-protein. 3: Mouse DLL1 Fc-protein. 4: Mouse DLL4 Fc protein. 5: Mouse Jagged-1 Fc-protein. 6: Unrelated Fc-protein (negative control). B) 1: Mouse DLK1 Fc-protein. 2: Mouse DLL1 Fc-protein. 3: Human DLK1 (ED) (FLAG ® -tagged). 4: 3T3L1 cell lysate. 100 μg Log in to see 5 to 8 Days
$330.75
Details
Human Mouse Un-conjugated FACS, IHC, ELISA, WB Immunohistochemical staining of DLK1 using anti-DLK1 (human), mAb (PF299-1)  in placenta, villi (1:500 dilution). This antibody has been tested in immunohistochemistry, analyzed by an anatomic pathologist and validated for use in IHC applications against formalin-fixed, paraffin-embedded human tissues. The image shows the localization of the antibody as the precipitated red signal, with a hematoxylin purple nuclear counterstain. Western blot analysis of human Pref-1using anti-DLK1 (human), mAb  (PF299-1)  at 1: 2,000 dilution. A. 1. Human Pref-1 Fc protein. 2. Transfected human Pref-1 full length cell lysate (HEK 293). 3. Mock Transfected HEK293 cell lysate. B. 1. Human Pref-1 Fc protein. 2. Mouse Pref-1 Fc protein. 3. Human DNER Fc protein. 4. Human DLL1 Fc protein. 5. Human DLL3 Fc protein. 6. Human DLL4 Fc protein. 7. Human Jagged1 Fc protein. 8. Human FGF23 Fc protein. 100 μg Log in to see 5 to 8 Days
$341.25
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in human placenta tissue (Formalin-fixed, Paraffin-embedded) using DLK1  Antibody , followed by peroxidase conjugated secondary antibody and DAB staining. This data demonstrates the use of DLK1 antibody for IHC. Clinical relevance has not been evaluated. Western blot analysis in CEM cell line lysates (35ug/lane) using DLK1  Antibody . This demonstrates the DLK1 antibody detected the DLK1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated ICC, FACS, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of NIH/3T3 cells using DLK1 mouse mAb (green) and negative control (red) . 100 μL Log in to see 2 to 3 Days
$430.10
Details
Guinea Pig Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details

DLK1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-DLK1 Antibodies

  1. Human Monoclonal DLK1 Primary Antibody for ICC, FACS - ABIN969086 : Espina, Méndez-Vidal, Moreno-Mateos, Sáez, Romero-Franco, Japón, Pintor-Toro: Induction of Dlk1 by PTTG1 inhibits adipocyte differentiation and correlates with malignant transformation. in Molecular biology of the cell 2009 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal DLK1 Primary Antibody for CyTOF, FACS - ABIN4899811 : Kim, Lin, Zelterman, Yun: Hypoxia-regulated delta-like 1 homologue enhances cancer cell stemness and tumorigenicity. in Cancer research 2009 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal DLK1 Primary Antibody for CyTOF, FACS - ABIN4899812 : Chung, Lapoint, Martinez, Kennedy, Boysen Sandberg, McIntosh: Preadipocytes mediate lipopolysaccharide-induced inflammation and insulin resistance in primary cultures of newly differentiated human adipocytes. in Endocrinology 2006 (PubMed)
    Show all 2 Pubmed References

  4. Dog (Canine) Polyclonal DLK1 Primary Antibody for WB - ABIN2773880 : Zhou, Wang, Wang, Zhu, Shu, Liao, Yu, Gao, Xi, Wang, Zhang, Yuan, Jiang: Global comparison of gene expression profiles between intramuscular and subcutaneous adipocytes of neonatal landrace pig using microarray. in Meat science 2010 (PubMed)

  5. Human Polyclonal DLK1 Primary Antibody for WB - ABIN522231 : Kilian, Beck-Sickinger: Recombinant expression and characterization of biologically active protein delta homolog 1. in Protein expression and purification 2015 (PubMed)

  6. Human Monoclonal DLK1 Primary Antibody for FACS, IHC - ABIN1169184 : Kluth, Radke, Kögler: Increased Haematopoietic Supportive Function of USSC from Umbilical Cord Blood Compared to CB MSC and Possible Role of DLK-1. in Stem cells international 2013 (PubMed)

  7. Mouse (Murine) Monoclonal DLK1 Primary Antibody for ELISA, WB - ABIN1169190 : Kim, Kang, Park, Kim, Park, Kim, Leem, Chu, Lee, Jho, Oh: Identification of a stroma-mediated Wnt/beta-catenin signal promoting self-renewal of hematopoietic stem cells in the stem cell niche. in Stem cells (Dayton, Ohio) 2009 (PubMed)

More Antibodies against DLK1 Interaction Partners

Cow (Bovine) delta-Like 1 Homolog (Drosophila) (DLK1) interaction partners

  1. DLK1 mRNA expression in mesenteric fat was higher than subcutaneous fat. DLK1 mRNA expression in Holstein cattle mesenteric fat was higher than Wagyu cattle.

  2. The four loci of DLK1 gene and CLPG gene in 1109 individuals, which belong to eight breeds/species of bovidae, including cattle, buffalo and yak, were analyzed.

  3. tissue-specific expression patterns of Dlk-1 splice variants in bovine tissues

Human delta-Like 1 Homolog (Drosophila) (DLK1) interaction partners

  1. SASH1 (show SASH1 Antibodies) acts through NOTCH1 (show NOTCH1 Antibodies) and its inhibitor DLK1 in a three-dimensional model of lumenogenesis involving CEACAM1 (show CEACAM1 Antibodies).

  2. The data presented in this work suggest that a fine regulation of NOTCH (show NOTCH1 Antibodies) signaling BY DLK1 plays an important role in the control of breast cancer cell proliferation and invasion.

  3. results demonstrate that miR (show MLXIP Antibodies)-129-5p inhibits non-small cell lung cancer stemness and chemoresistance through direct targeting of DLK1

  4. A complex defect of DLK1 ( approximately 14-kb deletion and 269-bp duplication) was identified in a family with central precocious puberty. This deletion included the 5' untranslated region and the first exon of DLK1, including the translational start site. Only family members who inherited the defect from their father have precocious puberty, consistent with the known imprinting of DLK1.

  5. Loss of DLK1 expression is associated with fetal growth retardation complications of pregnancy.

  6. In neonatal skin, DLK1 exhibited a high degree of monoallelic expression from the paternal allele.

  7. The study evaluated the roles of extracellular soluble DLK1, comprising six EGF (show EGF Antibodies)-like domains and juxtamembrane regions, in human pancreatic cancer MIA (show MIA Antibodies) PaCa-2 cells in vitro and in vivo. Soluble DLK1 exerted antitumor effects not only in cancer cell migration and anchorage-independent cell growth but also in in vivo tumor growth.

  8. Treatment of mice with recombinant human DLK1 during pregnancy has significant effects on AT of the offspring. This can be associated with counter-regulatory changes in the Notch1 (show NOTCH1 Antibodies) signaling cascade.

  9. NOTCH1 (show NOTCH1 Antibodies) ligand Delta-like 1 (show DLL1 Antibodies) homolog (DLK1) self interacts

  10. Pref-1 induces insulin (show INS Antibodies) synthesis and secretion via two independent pathways

Pig (Porcine) delta-Like 1 Homolog (Drosophila) (DLK1) interaction partners

  1. trans-associations occur between three imprinted genes IGF2, DLK1 and MEG3 both in fetal liver and muscle cells.

  2. We did not observe significantly different expression of DLK1, MEG3 or PEG11 (show RTL1 Antibodies) mRNA in any of analyzed breeds.

  3. QUASEP supports paternal expression of DLK1 in whole brain, carcass, liver and placental tissues of day 30 interbreed porcine fetuses.

  4. the sequence of porcine DLK1 (pDLK1)was examined,the expression and alternative splicing isoforms in the pig (Sus scrofa) was compared with human

  5. Polymorphisms, imprinting status and quantitative trait locus analyses of the porcine DLK1 and MEG3 genes i swine.

  6. Expression of DLK1 splice variants during adipocyte development in vitro and in vivo.

Mouse (Murine) delta-Like 1 Homolog (Drosophila) (DLK1) interaction partners

  1. Gene body methylation of noncoding RNA genes was observed and among these microRNA genes were prominent. Of particular note, observed only in hyperphenylalaninemic animals, was hypomethylation of miRNA genes within the imprinted Dlk1-Dio3 (show DIO3 Antibodies) locus on chromosome 12.

  2. The role of elevated oxygen levels in eroding imprinted Dlk1 expression during prolonged culture and in vitro differentiation.

  3. Loss of DLK1 expression is associated with fetal growth retardation complications of pregnancy.

  4. Pref-1 mRNA is a novel substrate of RNase-L (show RNASEL Antibodies).

  5. the conserved sequences in IG-DMR (show WDR20 Antibodies) are involved in the expression regulation of some of the imprinted genes in the Dlk1-Dio3 (show DIO3 Antibodies) domain

  6. To investigate the nature of these more variably methylated secondary differentially methylated regions, we adopted a hairpin linker bisulfite mutagenesis approach to examine CpG dyad methylation at differentially methylated regions associated with the murine Dlk1/Gtl2 imprinting cluster on both complementary strands.

  7. NOTCH1 (show NOTCH1 Antibodies) ligand Delta-like 1 (show DLL1 Antibodies) homolog (DLK1) self interacts

  8. the salivary gland phenotype of Dlk1 knock-out mice, was investigated.

  9. The brain-specific (show CALY Antibodies) miR (show MLXIP Antibodies)-379/miR (show MLXIP Antibodies)-410 gene cluster at the imprinted Dlk1-Dio3 (show DIO3 Antibodies) domain is implicated in several aspects of brain development and function.

  10. data provide the first evidence for a direct interaction between DLK1 and NOTCH1 (show NOTCH1 Antibodies) in mammals, and substantiate that non-canonical NOTCH (show NOTCH1 Antibodies) ligands exist, adding to the complexity of NOTCH (show NOTCH1 Antibodies) signaling.

DLK1 Antigen Profile

Protein Summary

This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes\; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance\; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.

Gene names and symbols associated with DLK1

  • delta like non-canonical Notch ligand 1 (DLK1) antibody
  • delta-like 1 homolog (Drosophila) (Dlk1) antibody
  • delta like non-canonical Notch ligand 1 (Dlk1) antibody
  • delta-like 1 homolog (Drosophila) (DLK1) antibody
  • AW742678 antibody
  • Delta1 antibody
  • DLK antibody
  • DLK-1 antibody
  • DlkI antibody
  • FA1 antibody
  • Ly107 antibody
  • Peg9 antibody
  • pG2 antibody
  • pref-1 antibody
  • PREF1 antibody
  • SCP1 antibody
  • Zog antibody

Protein level used designations for DLK1

delta-like homolog , preadipocyte factor-1 , protein delta homolog 1 , delta-like 1 homolog (Drosophila) , delta-like protein 1 , protein delta homolog 1-like , fetal antigen 1 , preadipocyte factor 1 , secredeltin , adipocyte differentiation inhibitor protein , stromal cell derived protein 1

GENE ID SPECIES
281117 Bos taurus
423459 Gallus gallus
490860 Canis lupus familiaris
707595 Macaca mulatta
100054933 Equus caballus
100082485 Ornithorhynchus anatinus
100303692 Meleagris gallopavo
100449207 Pongo abelii
100598289 Nomascus leucogenys
8788 Homo sapiens
497066 Sus scrofa
13386 Mus musculus
114587 Rattus norvegicus
641301 Ovis aries
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