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anti-delta-Like 1 Homolog (Drosophila) (DLK1) Antibodies

DLK1 encodes a transmembrane protein containing six epidermal growth factor repeats. Additionally we are shipping DLK1 Proteins (27) and DLK1 Kits (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DLK1 8788 P80370
DLK1 13386 Q09163
DLK1 114587  
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Top anti-DLK1 Antibodies at

Showing 10 out of 159 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Mouse Rat Un-conjugated IHC (fro), FACS, IHC (p) 0.1 mg Log in to see 6 to 8 Days
Mouse Rat FITC FACS 100 μL Log in to see 10 to 12 Days
Mouse Rat PE FACS 50 Tests Log in to see 6 to 8 Days
Mouse Rat Un-conjugated ELISA, WB Western blot analysis using anti-DLK1 (mouse), mAb (PF105B)  at 1:2'000 dilution. A) 1: Mouse DLK1 Fc-protein. 2: Human DLK1 Fc-protein. 3: Mouse DLL1 Fc-protein. 4: Mouse DLL4 Fc protein. 5: Mouse Jagged-1 Fc-protein. 6: Unrelated Fc-protein (negative control). B) 1: Mouse DLK1 Fc-protein. 2: Mouse DLL1 Fc-protein. 3: Human DLK1 (ED) (FLAG ® -tagged). 4: 3T3L1 cell lysate. 100 μg Log in to see 5 to 8 Days
Human Mouse Un-conjugated FACS, IHC, ELISA, WB Immunohistochemical staining of DLK1 using anti-DLK1 (human), mAb (PF299-1)  in placenta, villi (1:500 dilution). This antibody has been tested in immunohistochemistry, analyzed by an anatomic pathologist and validated for use in IHC applications against formalin-fixed, paraffin-embedded human tissues. The image shows the localization of the antibody as the precipitated red signal, with a hematoxylin purple nuclear counterstain. Western blot analysis of human Pref-1using anti-DLK1 (human), mAb  (PF299-1)  at 1: 2,000 dilution. A. 1. Human Pref-1 Fc protein. 2. Transfected human Pref-1 full length cell lysate (HEK 293). 3. Mock Transfected HEK293 cell lysate. B. 1. Human Pref-1 Fc protein. 2. Mouse Pref-1 Fc protein. 3. Human DNER Fc protein. 4. Human DLL1 Fc protein. 5. Human DLL3 Fc protein. 6. Human DLL4 Fc protein. 7. Human Jagged1 Fc protein. 8. Human FGF23 Fc protein. 100 μg Log in to see 5 to 8 Days
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in human placenta tissue (Formalin-fixed, Paraffin-embedded) using DLK1  Antibody , followed by peroxidase conjugated secondary antibody and DAB staining. This data demonstrates the use of DLK1 antibody for IHC. Clinical relevance has not been evaluated. Western blot analysis in CEM cell line lysates (35ug/lane) using DLK1  Antibody . This demonstrates the DLK1 antibody detected the DLK1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated EIA, WB Western blot analysis of HepG2 in 293 cell lysate with DLK1 Antibody  at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
Human Mouse Un-conjugated ICC, FACS, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of NIH/3T3 cells using DLK1 mouse mAb (green) and negative control (red) . 100 μL Log in to see 3 to 4 Days
Human Mouse Un-conjugated FACS, ICC, WB Detection of Pref-1/DLK1/FA1 in HepG2 Human Cell Line by Flow Cytometry. HepG2 human hepatocellular carcinoma cell line was stained with Mouse Anti-Human Pref-1/DLK1/FA1 Monoclonal Antibody. 100 μg Log in to see 6 to 7 Days

DLK1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-DLK1 Antibodies

  1. Mouse (Murine) Monoclonal DLK1 Primary Antibody for FACS - ABIN2853604 : Suzuki, Tanaka, Watanabe, Saito, Nonaka, Miyajima: p75 Neurotrophin receptor is a marker for precursors of stellate cells and portal fibroblasts in mouse fetal liver. in Gastroenterology 2008 (PubMed)
    Show all 3 references for ABIN2853604

  2. Mouse (Murine) Monoclonal DLK1 Primary Antibody for IHC (fro), FACS - ABIN1449213 : Tanimizu, Nishikawa, Saito, Tsujimura, Miyajima: Isolation of hepatoblasts based on the expression of Dlk/Pref-1. in Journal of cell science 2003 (PubMed)
    Show all 3 references for ABIN1449213

  3. Human Polyclonal DLK1 Primary Antibody for EIA, IHC (p) - ABIN951922 : Yanai, Nakamura, Hijioka, Kamei, Ikari, Ishikawa, Shinozaki, Mizunuma, Hatake, Miyajima: Dlk-1, a cell surface antigen on foetal hepatic stem/progenitor cells, is expressed in hepatocellular, colon, pancreas and breast carcinomas at a high frequency. in Journal of biochemistry 2010 (PubMed)
    Show all 2 references for ABIN951922

  4. Human Monoclonal DLK1 Primary Antibody for ICC, FACS - ABIN969086 : Espina, Méndez-Vidal, Moreno-Mateos, Sáez, Romero-Franco, Japón, Pintor-Toro: Induction of Dlk1 by PTTG1 inhibits adipocyte differentiation and correlates with malignant transformation. in Molecular biology of the cell 2009 (PubMed)
    Show all 2 references for ABIN969086

  5. Mouse (Murine) Monoclonal DLK1 Primary Antibody for FACS - ABIN1449215 : Kaneta, Osawa, Sudo, Nakauchi, Farr, Takahama: A role for pref-1 and HES-1 in thymocyte development. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
    Show all 2 references for ABIN1449215

  6. Human Monoclonal DLK1 Primary Antibody for FACS, ICC - ABIN4899811 : Kim, Lin, Zelterman, Yun: Hypoxia-regulated delta-like 1 homologue enhances cancer cell stemness and tumorigenicity. in Cancer research 2009 (PubMed)
    Show all 2 references for ABIN4899811

  7. Human Polyclonal DLK1 Primary Antibody for EIA, WB - ABIN1449988 : Smas, Sul: Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation. in Cell 1993 (PubMed)

  8. Mouse (Murine) Monoclonal DLK1 Primary Antibody for ELISA, WB - ABIN1169190 : Kim, Kang, Park, Kim, Park, Kim, Leem, Chu, Lee, Jho, Oh: Identification of a stroma-mediated Wnt/beta-catenin signal promoting self-renewal of hematopoietic stem cells in the stem cell niche. in Stem cells (Dayton, Ohio) 2009 (PubMed)

  9. Human Polyclonal DLK1 Primary Antibody for WB - ABIN2773880 : Zhou, Wang, Wang, Zhu, Shu, Liao, Yu, Gao, Xi, Wang, Zhang, Yuan, Jiang: Global comparison of gene expression profiles between intramuscular and subcutaneous adipocytes of neonatal landrace pig using microarray. in Meat science 2010 (PubMed)

  10. Human Monoclonal DLK1 Primary Antibody for FACS, IHC - ABIN1169184 : Kluth, Radke, Kögler: Increased Haematopoietic Supportive Function of USSC from Umbilical Cord Blood Compared to CB MSC and Possible Role of DLK-1. in Stem cells international 2013 (PubMed)

More Antibodies against DLK1 Interaction Partners

Cow (Bovine) delta-Like 1 Homolog (Drosophila) (DLK1) interaction partners

  1. DLK1 mRNA expression in mesenteric fat was higher than subcutaneous fat. DLK1 mRNA expression in Holstein cattle mesenteric fat was higher than Wagyu cattle.

  2. The four loci of DLK1 gene and CLPG gene in 1109 individuals, which belong to eight breeds/species of bovidae, including cattle, buffalo and yak, were analyzed.

  3. tissue-specific expression patterns of Dlk-1 splice variants in bovine tissues

Human delta-Like 1 Homolog (Drosophila) (DLK1) interaction partners

  1. NOTCH1 (show NOTCH1 Antibodies) ligand Delta-like 1 (show DLL1 Antibodies) homolog (DLK1) self interacts

  2. Pref-1 induces insulin (show INS Antibodies) synthesis and secretion via two independent pathways

  3. Data from longitudinal, nested case-control study conducted in rural South Korea suggest that low serum levels of DLK1 (preadipocyte factor 1) may be useful biomarker for identifying women (but not men) at high risk of developing insulin (show INS Antibodies) resistance, prediabetes, and type 2 diabetes.

  4. The appropriate timing of Dll1 (show DLL1 Antibodies) expression is critical for its oscillatory expression, pointing to the functional significance of Dll1 (show DLL1 Antibodies)-mediated oscillatory cell-cell interactions in the segmentation clock. [review]

  5. Results suggest a potential signalling hierarchy between Delta-like 1 (show DLL1 Antibodies) and ephrin-B2 (show EFNB2 Antibodies) ligands, as neural stem cells adopt the Delta-like 1 (show DLL1 Antibodies) phenotype of stem cell maintenance on simultaneous presentation of both signals.

  6. The results indicate the occurrence of epimutation affecting the IG-DMR (show WDR20 Antibodies) and the MEG3 (show FAM129B Antibodies)-DMR (show WDR20 Antibodies) in the two cases, and imply that UPD (show UROD Antibodies)(14)mat and related (epi (show TFPI Antibodies))genetic aberrations constitute a rare but important underlying factor for Silver-Russell Syndrome

  7. Kaplan-Meier analysis indicated that higher DLK1 levels were associated with shorter survival in Hepatocellular carcinoma (HCC (show FAM126A Antibodies)) patients. These results suggest that the serum levels of DLK1 may serve as a prognostic biomarker for HCC (show FAM126A Antibodies) patients.

  8. Notch (show NOTCH1 Antibodies) pathway activation in endothelial colony forming cells in vivo via co-implanted stromal cells expressing delta-like 1 (show DLL1 Antibodies) promotes vasculogenesis.

  9. Data show that the median expression of Jagged-1 (show JAG1 Antibodies) protein and delta-like 1 (show DLL1 Antibodies) protein (Dll-1 (show DLL1 Antibodies)) was significantly higher in acute myeloid leukemia (show BCL11A Antibodies) (AML (show RUNX1 Antibodies)) blasts than in peripheral blood stem cells (PBSCs).

  10. DLK1 expression diminishes during differentiation of human U937 cel (show NOTCH1 Antibodies)ls to macrophages.

Pig (Porcine) delta-Like 1 Homolog (Drosophila) (DLK1) interaction partners

  1. We did not observe significantly different expression of DLK1, MEG3 or PEG11 (show RTL1 Antibodies) mRNA in any of analyzed breeds.

  2. QUASEP supports paternal expression of DLK1 in whole brain, carcass, liver and placental tissues of day 30 interbreed porcine fetuses.

  3. the sequence of porcine DLK1 (pDLK1)was examined,the expression and alternative splicing isoforms in the pig (Sus scrofa) was compared with human

  4. Polymorphisms, imprinting status and quantitative trait locus analyses of the porcine DLK1 and MEG3 genes i swine.

  5. Expression of DLK1 splice variants during adipocyte development in vitro and in vivo.

Mouse (Murine) delta-Like 1 Homolog (Drosophila) (DLK1) interaction partners

  1. NOTCH1 (show NOTCH1 Antibodies) ligand Delta-like 1 (show DLL1 Antibodies) homolog (DLK1) self interacts

  2. the salivary gland phenotype of Dlk1 knock-out mice, was investigated.

  3. The brain-specific (show CALY Antibodies) miR (show MLXIP Antibodies)-379/miR (show MLXIP Antibodies)-410 gene cluster at the imprinted Dlk1-Dio3 (show DIO3 Antibodies) domain is implicated in several aspects of brain development and function.

  4. data provide the first evidence for a direct interaction between DLK1 and NOTCH1 (show NOTCH1 Antibodies) in mammals, and substantiate that non-canonical NOTCH (show NOTCH1 Antibodies) ligands exist, adding to the complexity of NOTCH (show NOTCH1 Antibodies) signaling.

  5. the Dlk1-Gtl2 locus plays a critical role in preserving long-term repopulating HSCs (LT-HSCs).

  6. DNA methylation (show HELLS Antibodies) regulates genomic imprinted DLK1-Dio3 (show DIO3 Antibodies) miRNAs in autoimmune lupus

  7. identify the molecular regulators involved in the recruitment of AFF3 (show AFF3 Antibodies) to gDMRs and provide mechanistic insight into the requirement of AFF3 (show AFF3 Antibodies) at an enhancer for the expression of an approximately 200-kb polycistronic transcript within the imprinted Dlk1-Dio3 (show DIO3 Antibodies) locus

  8. Dppa3 (show DPPA3 Antibodies) has a critical role in generation of fully reprogrammed iPS (show SLC27A4 Antibodies) cells and maintenance of Dlk1-Dio3 (show DIO3 Antibodies) imprinting

  9. results suggest that maternal expression of the imprinted miR (show MLXIP Antibodies)-379/miR (show MLXIP Antibodies)-544 cluster regulates paternal expression of the Dlk1 gene in mice

  10. Dll1 (show DLL1 Antibodies) and Jag1 (show JAG1 Antibodies), Notch (show NOTCH1 Antibodies) ligands, function redundantly and are necessary to maintain the centroacinar cells as an environmental niche in the developing pancreas.

DLK1 Antigen Profile

Protein Summary

This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes\; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance\; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.

Gene names and symbols associated with DLK1

  • delta-like 1 homolog (Drosophila) (DLK1) antibody
  • delta-like 1 homolog (Drosophila) (Dlk1) antibody
  • AW742678 antibody
  • Delta1 antibody
  • DLK antibody
  • DLK-1 antibody
  • DlkI antibody
  • FA1 antibody
  • Ly107 antibody
  • Peg9 antibody
  • pG2 antibody
  • pref-1 antibody
  • PREF1 antibody
  • SCP1 antibody
  • Zog antibody

Protein level used designations for DLK1

delta-like homolog , preadipocyte factor-1 , protein delta homolog 1 , delta-like 1 homolog (Drosophila) , delta-like protein 1 , protein delta homolog 1-like , fetal antigen 1 , preadipocyte factor 1 , secredeltin , adipocyte differentiation inhibitor protein , stromal cell derived protein 1

281117 Bos taurus
423459 Gallus gallus
490860 Canis lupus familiaris
707595 Macaca mulatta
100054933 Equus caballus
100082485 Ornithorhynchus anatinus
100303692 Meleagris gallopavo
100449207 Pongo abelii
100598289 Nomascus leucogenys
8788 Homo sapiens
497066 Sus scrofa
13386 Mus musculus
114587 Rattus norvegicus
641301 Ovis aries
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