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DLK1 encodes a transmembrane protein containing six epidermal growth factor repeats. Additionally we are shipping DLK1 Antibodies (171) and DLK1 Proteins (27) and many more products for this protein.
Showing 2 out of 12 products:
Mouse (Murine) DLK1 ELISA Kit for Sandwich ELISA - ABIN858465
Kessler, Laggai, Barghash, Schultheiss, Lederer, Artl, Helms, Haybaeck, Kiemer: IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype. in Cell death & disease 2015
DLK1 mRNA expression in mesenteric fat was higher than subcutaneous fat. DLK1 mRNA expression in Holstein cattle mesenteric fat was higher than Wagyu cattle.
The four loci of DLK1 gene and CLPG gene in 1109 individuals, which belong to eight breeds/species of bovidae, including cattle, buffalo and yak, were analyzed.
tissue-specific expression patterns of Dlk-1 splice variants in bovine tissues
The study evaluated the roles of extracellular soluble DLK1, comprising six EGF (show EGF ELISA Kits)-like domains and juxtamembrane regions, in human pancreatic cancer MIA (show MIA ELISA Kits) PaCa-2 cells in vitro and in vivo. Soluble DLK1 exerted antitumor effects not only in cancer cell migration and anchorage-independent cell growth but also in in vivo tumor growth.
Treatment of mice with recombinant human DLK1 during pregnancy has significant effects on AT of the offspring. This can be associated with counter-regulatory changes in the Notch1 (show NOTCH1 ELISA Kits) signaling cascade.
NOTCH1 (show NOTCH1 ELISA Kits) ligand Delta-like 1 (show DLL1 ELISA Kits) homolog (DLK1) self interacts
Pref-1 induces insulin (show INS ELISA Kits) synthesis and secretion via two independent pathways
Data from longitudinal, nested case-control study conducted in rural South Korea suggest that low serum levels of DLK1 (preadipocyte factor 1) may be useful biomarker for identifying women (but not men) at high risk of developing insulin (show INS ELISA Kits) resistance, prediabetes, and type 2 diabetes.
The appropriate timing of Dll1 (show DLL1 ELISA Kits) expression is critical for its oscillatory expression, pointing to the functional significance of Dll1 (show DLL1 ELISA Kits)-mediated oscillatory cell-cell interactions in the segmentation clock. [review]
Results suggest a potential signalling hierarchy between Delta-like 1 (show DLL1 ELISA Kits) and ephrin-B2 (show EFNB2 ELISA Kits) ligands, as neural stem cells adopt the Delta-like 1 (show DLL1 ELISA Kits) phenotype of stem cell maintenance on simultaneous presentation of both signals.
The results indicate the occurrence of epimutation affecting the IG-DMR (show WDR20 ELISA Kits) and the MEG3 (show FAM129B ELISA Kits)-DMR (show WDR20 ELISA Kits) in the two cases, and imply that UPD (show UROD ELISA Kits)(14)mat and related (epi (show TFPI ELISA Kits))genetic aberrations constitute a rare but important underlying factor for Silver-Russell Syndrome
Kaplan-Meier analysis indicated that higher DLK1 levels were associated with shorter survival in Hepatocellular carcinoma (HCC (show FAM126A ELISA Kits)) patients. These results suggest that the serum levels of DLK1 may serve as a prognostic biomarker for HCC (show FAM126A ELISA Kits) patients.
Notch (show NOTCH1 ELISA Kits) pathway activation in endothelial colony forming cells in vivo via co-implanted stromal cells expressing delta-like 1 (show DLL1 ELISA Kits) promotes vasculogenesis.
trans-associations occur between three imprinted genes IGF2, DLK1 and MEG3 both in fetal liver and muscle cells.
We did not observe significantly different expression of DLK1, MEG3 or PEG11 (show RTL1 ELISA Kits) mRNA in any of analyzed breeds.
QUASEP supports paternal expression of DLK1 in whole brain, carcass, liver and placental tissues of day 30 interbreed porcine fetuses.
the sequence of porcine DLK1 (pDLK1)was examined,the expression and alternative splicing isoforms in the pig (Sus scrofa) was compared with human
Polymorphisms, imprinting status and quantitative trait locus analyses of the porcine DLK1 and MEG3 genes i swine.
Expression of DLK1 splice variants during adipocyte development in vitro and in vivo.
the salivary gland phenotype of Dlk1 knock-out mice, was investigated.
The brain-specific (show CALY ELISA Kits) miR (show MLXIP ELISA Kits)-379/miR (show MLXIP ELISA Kits)-410 gene cluster at the imprinted Dlk1-Dio3 (show DIO3 ELISA Kits) domain is implicated in several aspects of brain development and function.
data provide the first evidence for a direct interaction between DLK1 and NOTCH1 (show NOTCH1 ELISA Kits) in mammals, and substantiate that non-canonical NOTCH (show NOTCH1 ELISA Kits) ligands exist, adding to the complexity of NOTCH (show NOTCH1 ELISA Kits) signaling.
the Dlk1-Gtl2 locus plays a critical role in preserving long-term repopulating HSCs (LT-HSCs).
DNA methylation (show HELLS ELISA Kits) regulates genomic imprinted DLK1-Dio3 (show DIO3 ELISA Kits) miRNAs in autoimmune lupus
identify the molecular regulators involved in the recruitment of AFF3 (show AFF3 ELISA Kits) to gDMRs and provide mechanistic insight into the requirement of AFF3 (show AFF3 ELISA Kits) at an enhancer for the expression of an approximately 200-kb polycistronic transcript within the imprinted Dlk1-Dio3 (show DIO3 ELISA Kits) locus
Dppa3 (show DPPA3 ELISA Kits) has a critical role in generation of fully reprogrammed iPS (show SLC27A4 ELISA Kits) cells and maintenance of Dlk1-Dio3 (show DIO3 ELISA Kits) imprinting
results suggest that maternal expression of the imprinted miR (show MLXIP ELISA Kits)-379/miR (show MLXIP ELISA Kits)-544 cluster regulates paternal expression of the Dlk1 gene in mice
Dll1 (show DLL1 ELISA Kits) and Jag1 (show JAG1 ELISA Kits), Notch (show NOTCH1 ELISA Kits) ligands, function redundantly and are necessary to maintain the centroacinar cells as an environmental niche in the developing pancreas.
This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes\; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance\; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.
, preadipocyte factor-1
, protein delta homolog 1
, delta-like 1 homolog (Drosophila)
, delta-like protein 1
, protein delta homolog 1-like
, fetal antigen 1
, preadipocyte factor 1
, adipocyte differentiation inhibitor protein
, stromal cell derived protein 1