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serine/threonine Kinase 4 (STK4) ELISA Kits

The protein encoded by STK4 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. Additionally we are shipping STK4 Antibodies (77) and STK4 Proteins (16) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human STK4 STK4 6789 Q13043
STK4 58231 Q9JI11
Anti-Rat STK4 STK4 311622  
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Top STK4 ELISA Kits at

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 10pg/mL 156-10.000 pg/mL Mouse MSP/MST1 PicoKine ELISA Kit standard curve 96 Tests Log in to see 4 to 6 Days

Top referenced STK4 ELISA Kits

  1. Mouse (Murine) STK4 ELISA Kit for Sandwich ELISA - ABIN1889361 : Han, Stuart, Degen: Characterization of the DNF15S2 locus on human chromosome 3: identification of a gene coding for four kringle domains with homology to hepatocyte growth factor. in Biochemistry 1991 (PubMed)
    Show all 3 references for ABIN1889361

More ELISA Kits for STK4 Interaction Partners

Human serine/threonine Kinase 4 (STK4) interaction partners

  1. Mst1 (show MST1 ELISA Kits) as a novel physiological negative regulator of IRF3 (show IRF3 ELISA Kits) activation provides mechanistic insights into innate antiviral defense and potential antiviral prevention strategies.

  2. Data indicate that two siblings with a serine/threonine kinase 4 (STK4) mutation with features of autosomal recessive (AR) hyperimmunoglobulin E syndrome and autoimmune cytopenias.

  3. STK4 was reduced in macrophages from human hepatoma patients and was inversely associated with the levels of IRAK1, IL-6, and phospho-p65 or phospho-STAT3. Serum STK4 levels were specifically decreased in HCC patients with high levels of IL-6.

  4. The MST1/2-SAV1 complex, a core component of the Hippo pathway, promotes ciliogenesis.

  5. the kinase Mst1 (show MST1 ELISA Kits) controls selective CCR7 (show CCR7 ELISA Kits)-dependent functions in human mature dendritic cells.

  6. Genetic inactivation of STK4 restores YAP1 (show YAP1 ELISA Kits) levels, triggering cell death in hematologic malignancies.

  7. Results indicate that changes in phosphorylation orchestrate interactions between kinases and phosphatases in Hippo (MST1 (show MST1 ELISA Kits)/2 protein kinases) signaling, providing a putative mechanism for pathway regulation.

  8. Inhibition of Mst1 (show MST1 ELISA Kits) kinase activation in cardiomyocytes protects against cell hypoxia.

  9. Under diabetogenic conditions, MST1 (show MST1 ELISA Kits) was strongly activated in beta cells, and induced apoptosis via BIM (show BCL2L11 ELISA Kits) upregulation, and impaired insulin (show INS ELISA Kits) secretion via phosphorylation of PDX1 (show PDX1 ELISA Kits).

  10. PHLPP1 (show PHLPP1 ELISA Kits) is a binding protein for Mst1 (show MST1 ELISA Kits) and it modulates the Hippo pathway by dephosphorylating Mst1 (show MST1 ELISA Kits) at the inhibitory Thr (show TRH ELISA Kits)(387) of Mst1 (show MST1 ELISA Kits).

Mouse (Murine) serine/threonine Kinase 4 (STK4) interaction partners

  1. mammalian sterile 20-like kinase 1 (Mst1) knockout abolished the protective effects of Luteolin administration in a mouse model of myocardial infarction.

  2. Studies indicate that Hippo (Hpo (show GFER ELISA Kits); MST1 (show MST1 ELISA Kits)/2 in mammals) signaling pathway plays a central role in the cell fate-specification process.

  3. Data (including data from studies in knockout/transgenic mice) suggest Mst1 (show MST1 ELISA Kits) has functional roles in cytotoxic T-lymphocytes and in inhibition of tumor progression/size of T-cell lymphoma; Mst1 (show MST1 ELISA Kits) may be involved in tumor immunity/immunologic surveillance.

  4. the TLR-Mst1 (show MST1 ELISA Kits)-Mst2 (show STK3 ELISA Kits)-Rac (show AKT1 ELISA Kits) signaling axis is critical for effective phagosome-mitochondrion function and bactericidal activity

  5. Macrophage-specific Stk4 deletion resulted in chronic inflammation, liver fibrosis, and hepatomas in mice exposed to liver insult.

  6. STK4 is a novel candidate biomarker for early stage pancreatic cancer.

  7. Phosphorylation of LC3 (show MAP1LC3A ELISA Kits) by the STK3 (show PKN1 ELISA Kits) and STK4 is essential for autophagy.

  8. These results identify MST2 (show STK3 ELISA Kits), not MST1 (show MST1 ELISA Kits), as a critical regulator of caspase (show CASP3 ELISA Kits)-mediated photoreceptor cell death in the detached retina and indicate its potential as a future neuroprotection target.

  9. Mst1 (show MST1 ELISA Kits)/2 regulate placental development by control of trophoblast cell differentiation and labyrinthine vasculature at midgestation and Mst1 (show MST1 ELISA Kits)/2 control labyrinth morphogenesis in trophoblast- and fetal endothelial-dependent manners.

  10. Mst1 (show MST1 ELISA Kits) is required for Treg cells to mediate contact-dependent suppressor functions.

STK4 Antigen Profile

Antigen Summary

The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.

Gene names and symbols associated with STK4

  • serine/threonine kinase 4 (STK4) antibody
  • serine/threonine kinase 4 (Stk4) antibody
  • serine/threonine kinase 4 (stk4) antibody
  • AI447339 antibody
  • AU020804 antibody
  • Kas-2 antibody
  • krs2 antibody
  • mst1 antibody
  • TIIAC antibody
  • ysk3 antibody

Protein level used designations for STK4

MST-1 , STE20-like kinase MST1 , dJ211D12.2 (serine/threonine kinase 4 (MST1, KRS2)) , kinase responsive to stress 2 , mammalian STE20-like protein kinase 1 , mammalian sterile 20-like 1 , serine/threonine-protein kinase 4 , serine/threonine-protein kinase Krs-2 , Yeast Sps1/Ste20-related kinase 3 , sterile 20-like kinase 1

6789 Homo sapiens
58231 Mus musculus
311622 Rattus norvegicus
514886 Bos taurus
419187 Gallus gallus
717730 Macaca mulatta
398925 Xenopus laevis
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