Browse our LRRC32 Proteins (LRRC32)

On www.antibodies-online.com are 9 Leucine Rich Repeat Containing 32 (LRRC32) Proteins from 6 different suppliers available. Additionally we are shipping LRRC32 Antibodies (73) and LRRC32 Kits (1) and many more products for this protein. A total of 84 LRRC32 products are currently listed.
Synonyms:
AI426318, D7H11S833E, D11S833E, D11S833Eh, EG434215, Garp
list all proteins Gene Name GeneID UniProt
LRRC32 2615 Q14392
LRRC32 434215  
LRRC32 293135  

LRRC32 Proteins (LRRC32) by Origin

More Proteins for LRRC32 Interaction Partners

Human Leucine Rich Repeat Containing 32 (LRRC32) interaction partners

  1. study showed that stimulated, human B lymphocytes produce active TGF-beta1 from surface GARP/latent TGF-beta1 complexes with isotype switching to IgA production.

  2. GARP (show CNGB1 Proteins) plays an important role in the pathogenesis of atopic dermatitis.

  3. CD4 (show CD4 Proteins)(+) CD25 (show IL2RA Proteins)(+) GARP (show CNGB1 Proteins)(+) Treg cells are defective in dilated cardiomyopathy patients and GARP (show CNGB1 Proteins) seems to be a better molecular definition of the regulatory phenotype.

  4. these results define the oncogenic effects of the GARP (show CNGB1 Proteins)-TGFbeta (show TGFB1 Proteins) axis in the tumor microenvironment

  5. LRRC32 expression is significantly upregulated in human masticatory mucosa during wound healing

  6. GARP (show CNGB1 Proteins) deficiency leads to accumulation of sphingolipid synthesis intermediates, changes in sterol distribution, and lysosomal dysfunction.

  7. since GARP (show CNGB1 Proteins) functions as a transporter of transforming growth factor beta (TGFbeta (show TGFB1 Proteins)), a cytokine with broad pleiotropic traits, GARP (show CNGB1 Proteins) transcriptional attenuation by alternative promoters might provide a mechanism regulating peripheral TGFb (show TGFB1 Proteins)

  8. GARP (show CNGB1 Proteins) is regulated by miRNAs and controls latent TGF-beta1 (show TGFB1 Proteins) production by human regulatory T cells.

  9. we investigated in detail miR (show MLXIP Proteins)-142-3 pregulation of GARP (show CNGB1 Proteins) expression in regulatory CD25 (show IL2RA Proteins)(+) CD4 (show CD4 Proteins) T cells

  10. Findings support the idea that GARP (show CNGB1 Proteins) is a new latent TGFbeta-binding protein (show LTBP1 Proteins) that regulates the bioavailability of TGFbeta (show TGFB1 Proteins) and provides a cell surface platform for alphaV integrin (show ITGAV Proteins)-dependent TGFbeta (show TGFB1 Proteins) activation.

Mouse (Murine) Leucine Rich Repeat Containing 32 (LRRC32) interaction partners

  1. These results demonstrate the unexpected presence of GARP on Hepatic stellate cells and its significance in regard to the ability of Hepatic stellate cells to activate latent TGF-beta1 (show TGFB1 Proteins) and thereby inhibit T cells.

  2. GARP expression on MSCs contributed to their ability to inhibit T-cell responses in vitro.

  3. We conclude that a missense mutation in VPS54, an essential component of the Golgi-associated retrograde protein complex, not only prevents the formation of an acrosome but also initiates a cascade of metabolic abnormalities and a stress reaction.

  4. These findings suggest a role for GARP in natural and induced Treg development through activation of bound latent TGF-beta (show TGFB1 Proteins) and signaling, which negatively regulates GARP expression on Tregs.

  5. GARP is a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 (show FOXP3 Proteins) expression

LRRC32 Protein Profile

Protein Summary

This gene encodes a type I membrane protein which contains 20 leucine-rich repeats. Alterations in the chromosomal region 11q13-11q14 are involved in several pathologies.

Alternative names and synonyms associated with LRRC32

  • leucine rich repeat containing 32 (LRRC32)
  • leucine rich repeat containing 32 (Lrrc32)
  • AI426318 protein
  • D7H11S833E protein
  • D11S833E protein
  • D11S833Eh protein
  • EG434215 protein
  • Garp protein

Protein level used designations for LRRC32

leucine rich repeat containing 32 , leucine-rich repeat-containing protein 32 , leucine-rich repeat-containing protein 32-like , garpin , glycoprotein A repetitions predominant

GENE ID SPECIES
428121 Gallus gallus
485180 Canis lupus familiaris
615467 Bos taurus
697438 Macaca mulatta
100028199 Monodelphis domestica
100522452 Sus scrofa
2615 Homo sapiens
434215 Mus musculus
293135 Rattus norvegicus
100171595 Pongo abelii
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