Browse our anti-PIK3AP1 (PIK3AP1) Antibodies

Full name:
anti-phosphoinositide-3-Kinase Adaptor Protein 1 Antibodies (PIK3AP1)
On www.antibodies-online.com are 91 phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) Antibodies from 14 different suppliers available. Additionally we are shipping PIK3AP1 Proteins (8) and PIK3AP1 Kits (4) and many more products for this protein. A total of 106 PIK3AP1 products are currently listed.
Synonyms:
1810044J04Rik, BCAP, RP11-34E5.3
list all antibodies Gene Name GeneID UniProt
PIK3AP1 118788 Q6ZUJ8
PIK3AP1 83490 Q9EQ32
PIK3AP1 294048  

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anti-Human PIK3AP1 Antibodies:

anti-Mouse (Murine) PIK3AP1 Antibodies:

anti-Rat (Rattus) PIK3AP1 Antibodies:

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Top referenced anti-PIK3AP1 Antibodies

  1. Human Polyclonal PIK3AP1 Primary Antibody for EIA, WB - ABIN954143 : Koutros, Schumacher, Hayes, Ma, Huang, Albanes, Canzian, Chanock, Crawford, Diver, Feigelson, Giovanucci, Haiman, Henderson, Hunter, Kaaks, Kolonel, Kraft, Le Marchand, Riboli, Siddiq, Stampfer, Stram, Thomas, Travis, Thun, Yeager, Berndt: Pooled analysis of phosphatidylinositol 3-kinase pathway variants and risk of prostate cancer. in Cancer research 2010 (PubMed)
    Show all 5 references for 954143

More Antibodies against PIK3AP1 Interaction Partners

Human phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) interaction partners

  1. Dimeric BCAP (show PHF11 Antibodies) associates with the TIR domains of TLR2 (show TLR2 Antibodies)/4 and MAL/TIRAP (show TIRAP Antibodies), suggesting that it is recruited to the TLR signalosome by multitypic TIR-TIR interactions.

  2. Abi-1 (show ABI1 Antibodies) promotes Abl (show ABL1 Antibodies)-mediated BCAP (show PHF11 Antibodies) phosphorylation and suggest that Abi-1 (show ABI1 Antibodies) in general coordinates kinase-substrate interactions

Mouse (Murine) phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) interaction partners

  1. identify BCAP as a novel inhibitor of myelopoiesis in the steady state and of emergency myelopoiesis during demand conditions

  2. Nck (show NCK1 Antibodies)-mediated recruitment of BCAP to the BCR (show BCR Antibodies) regulates the PI(3 (show PI3 Antibodies))K-Akt (show AKT1 Antibodies) pathway in B cells.

  3. BCAP is an essential activator of the PI3K pathway downstream of TLR signaling.

  4. BCAP is a unique TIR domain-containing toll (show TLR4 Antibodies) like receptor (TLR) signaling adapter crucial for linking TLRs to PI3K activation and regulating the inflammatory response.

  5. As macrophages engage their pathogenic targets, innate immune receptors trigger increased expression of BCAP, which endows them with the capacity to withstand further challenges from ongoing cellular insults, such as endoplasmic reticulum stress.

  6. BCAP-(L) (but not BCAP-(S)) is a negative regulator of the TLR-mediated host defense system in macrophages.

  7. BCAP and CD19 have complementary roles in BCR-mediated phosphoinositide 3-kinase activation

  8. model in which blunting of BCAP-mediated activation signaling in developing NK cells promotes functionality, terminal maturation, and long-term survival

PIK3AP1 Antigen Profile

Antigen Summary

Involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. Couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. Seems to have a complementary role with CD19 in PI3K activation (By similarity). May be involved in the survival of mature B-cells via activation of REL (By similarity).

Alternative names and synonyms associated with PIK3AP1

  • phosphoinositide-3-kinase adaptor protein 1 (PIK3AP1) antibody
  • phosphoinositide-3-kinase adaptor protein 1 (Pik3ap1) antibody
  • 1810044J04Rik antibody
  • BCAP antibody
  • RP11-34E5.3 antibody

Protein level used designations for PIK3AP1

B cell adaptor protein , B-cell adapter for phosphoinositide 3-kinase , B-cell phosphoinositide 3-kinase adapter protein 1 , phosphoinositide 3-kinase adapter protein 1 , B cell phosphoinositide 3-kinase adaptor

GENE ID SPECIES
118788 Homo sapiens
83490 Mus musculus
294048 Rattus norvegicus
608653 Canis lupus familiaris
374268 Gallus gallus
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