Browse our TMEM173 (TMEM173) ELISA Kits

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Transmembrane Protein 173 ELISA Kits (TMEM173)
On www.antibodies-online.com are 3 Transmembrane Protein 173 (TMEM173) ELISA Kits from 2 different suppliers available. Additionally we are shipping TMEM173 Antibodies (140) and TMEM173 Proteins (11) and many more products for this protein. A total of 161 TMEM173 products are currently listed.
Synonyms:
2610307O08Rik, ERIS, Mita, MPYS, NET23, RGD1562552, STING
list all ELISA KIts Gene Name GeneID UniProt
TMEM173 340061 Q86WV6
TMEM173 72512 Q3TBT3
Rat TMEM173 TMEM173 498840  

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TMEM173 (TMEM173) ELISA Kits by Reactivity

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More ELISA Kits for TMEM173 Interaction Partners

Human Transmembrane Protein 173 (TMEM173) interaction partners

  1. Human herpesvirus 1 ICP27 interacted with TBK1 (show TBK1 ELISA Kits) and STING in a manner that was dependent on TBK1 (show TBK1 ELISA Kits) activity and the RGG motif in ICP27 and inhibited type I IFN induction through the cGAS-STING-TBK1 (show TBK1 ELISA Kits) pathway in human macrophages.

  2. Multivariate analysis supported TMEM173 as an independent prognostic factor.

  3. The mitochondrial damage-cGAS-STING-IRF3 (show IRF3 ELISA Kits) pathway is critically involved in metabolic stress-induced endothelial inflammation.

  4. These data uncover a promycobacterial role for STING-dependent OASL (show OASL ELISA Kits) production during Mycobacterium leprae infection that directs the host immune response toward a niche that permits survival of the pathogen.

  5. cGAs recognizes bacterial/viral DNA, and is a strong activator of STING that can further activate IRF3 (show IRF3 ELISA Kits) and subsequent type I interferon (show IFNA ELISA Kits) production. (Review)

  6. Primary human endothelial cells mount robust type I interferon (show IFNA ELISA Kits) responses to human cytomegalovirus that are dependent upon cyclic GMP (show NT5C2 ELISA Kits)-AMP (show APRT ELISA Kits) synthase (cGAS), STING, and interferon regulatory factor 3 (IRF3 (show IRF3 ELISA Kits)) signaling.

  7. The regulation of STING via RIG-I (show DDX58 ELISA Kits)-mediated innate immune sensing.

  8. The study demonstrates the lack of association between the presence of systemic autoimmune diseases and mutations in exon 5 of the TMEM173 gene.

  9. cGAS and STING are intracellular sensors that activate the interferon (show IFNA ELISA Kits) pathway in response to virus infection. [review]

  10. Studies suggest that the transmembrane protein 173 (STING) pathway is the main innate immune pathway involved in sensing of tumors, and its endogenous activation in APCs (show APCS ELISA Kits) leads to subsequent T cell priming against tumor-associated antigens.

Mouse (Murine) Transmembrane Protein 173 (TMEM173) interaction partners

  1. results suggest that LSm14A (show LSM14A ELISA Kits) plays an important role in antiviral innate and adaptive immune responses by modulating MITA level in a cell type-specific manner

  2. STING and TRIF (show RNF138 ELISA Kits) Contribute to Mouse Sepsis, Depending on Severity of the Disease Model

  3. Data suggest that activation of either RIG-I (show DDX58 ELISA Kits)/MAVS (show MAVS ELISA Kits) or STING pathways during acute intestinal tissue injury in mice resulted in IFN-I signaling that maintained gut (show GUSB ELISA Kits) epithelial barrier integrity and reduced GVHD severity.

  4. this study shows that iRhom2 is essential for STING activity, as it regulates TRAPbeta-mediated translocation and EIF3S5-mediated deubiquitination of STING

  5. The mitochondrial damage-cGAS-STING-IRF3 (show IRF3 ELISA Kits) pathway is critically involved in metabolic stress-induced endothelial inflammation.

  6. NLRX1 (show NLRX1 ELISA Kits) sequesters the DNA-sensing adaptor STING from interaction with TBK1 (show TBK1 ELISA Kits), which is a requisite for IFN-1 induction in response to viral DNA.

  7. Data show that the formation of a tripartite ribosomal protein S6 kinase 1 (S6K1 (show RPS6KB1 ELISA Kits))-STING membrane protein-TANK-binding kinase 1 (TBK1 (show TBK1 ELISA Kits)) complex was necessary for the activation of interferon regulatory factor-3 (IRF3 (show IRF3 ELISA Kits)).

  8. Sting protein role in the innate immune response and interferon (show IFNA ELISA Kits)-stimulated genes response pathway

  9. required for chitosan-mediated enhancement of antigen specific Th1 (show HAND1 ELISA Kits) and immunoglobulin G2 responses following vaccination

  10. in vitro activation of the AIM2 (show AIM2 ELISA Kits) inflammasome in murine macrophages and dendritic cells leads to reduced activation of the STING pathway, in part through promoting caspase-1 (show CASP1 ELISA Kits)-dependent cell death.

Pig (Porcine) Transmembrane Protein 173 (TMEM173) interaction partners

TMEM173 Antigen Profile

Antigen Summary

Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double- stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti- viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.

Alternative names and synonyms associated with TMEM173

  • transmembrane protein 173 (TMEM173) Elisa Kit
  • transmembrane protein 173 (Tmem173) Elisa Kit
  • 2610307O08Rik Elisa Kit
  • ERIS Elisa Kit
  • Mita Elisa Kit
  • MPYS Elisa Kit
  • NET23 Elisa Kit
  • RGD1562552 Elisa Kit
  • STING Elisa Kit

Protein level used designations for TMEM173

transmembrane protein 173 , N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner , endoplasmic reticulum IFN stimulator , endoplasmic reticulum interferon stimulator , hMITA , hSTING , mediator of IRF3 activation , mitochondrial mediator of IRF3 activation , stimulator of interferon genes protein , MMITA , mSTING , Stimulator of interferon genes protein , mitochondrial transmembrane protein 173

GENE ID SPECIES
606815 Canis lupus familiaris
462107 Pan troglodytes
694353 Macaca mulatta
100459760 Pongo abelii
340061 Homo sapiens
72512 Mus musculus
533661 Bos taurus
768990 Gallus gallus
100217389 Sus scrofa
498840 Rattus norvegicus
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