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Browse our Ubiquitin-Conjugating Enzyme E2D 2 Proteins (UBE2D2)

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Ubiquitin-Conjugating Enzyme E2D 2 Proteins (UBE2D2)
On are 17 Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) Proteins from 8 different suppliers available. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2D 2 Antibodies (83) and many more products for this protein. A total of 109 Ubiquitin-Conjugating Enzyme E2D 2 products are currently listed.
1500034D03Rik, E2(17)KB2, E217kB, PUBC1, Ubc2e, ubc4, UBC4/5, UBCH5B, Ube2d2, ube2d3.1, wu:fj13d01, xubc4, zgc:55886, zgc:73200
list all proteins Gene Name GeneID UniProt
UBE2D2 7322 P62837
Rat UBE2D2 UBE2D2 641452 P62839
Mouse UBE2D2 UBE2D2 56550 P62838

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Ubiquitin-Conjugating Enzyme E2D 2 Proteins (UBE2D2) by Origin

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Top referenced Ubiquitin-Conjugating Enzyme E2D 2 Proteins

  1. Human UBE2D2 Protein expressed in Escherichia coli (E. coli) - ABIN667507 : Ciechanover, Schwartz: The ubiquitin-mediated proteolytic pathway: mechanisms of recognition of the proteolytic substrate and involvement in the degradation of native cellular proteins. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1994 (PubMed)
    Show all 2 references for ABIN667507

More Proteins for Ubiquitin-Conjugating Enzyme E2D 2 Interaction Partners

Human Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) interaction partners

  1. These results point to an important role of the affinity between RNF4 (show RNF4 Proteins) and its cognate RAD6B (show UBE2B Proteins) or UBCH5B in governing the multiplicity of substrate ubiquitination.

  2. Knockdown of UBE2D2 caused an increase in p53 (show TP53 Proteins) protein levels, and knockdown of p53 (show TP53 Proteins) attenuated not only cadmium-induced apoptosis, but also cadmium-induced apoptosis-related gene expression.

  3. mutations having marked effects on function only minimally affect the intermolecular interactions between the AO7 (show RNF25 Proteins) RING and UbcH5B, establishing a high degree of complexity in activation through the RING-E2 interface.

  4. Data show that ubiquitin E2 enzymes UBE2D1 (show UBE2D1 Proteins)/2/3 and E3 ligase RNF138 (show RNF138 Proteins) accumulate at DNA-damage sites and act at early resection stages by promoting CtIP (show RBBP8 Proteins) protein ubiquitylation and accrual.

  5. together with UBE2L3 (show UBE2L3 Proteins) and UBE2N (show UBE2N Proteins), synergistically contribute to Parkin (show PARK2 Proteins)-mediated mitophagy

  6. Presented is the structure of the human dimeric RING domain from BIRC7 (show BIRC7 Proteins) in complex with the E2 UbcH5B covalently linked to Ub.

  7. Whereas UbcH5(A, B and C) is highly efficient in converting IkBa into monoubiquitinated forms, Cdc34 drives ubiquitin (Ub)-Ub conjugation

  8. determined the 2.2 A crystal structure of an intermediate of UbcH5b approximately ubiquitin (Ub) conjugate, which is assembled into an infinite spiral through the backside interaction.

  9. role of WW3 and WW4 domains of Nedd4-2 in dopamine transporter ubiquitination was demonstrated; siRNA analysis demonstrated that this polyubiquitination is mediated by Nedd4-2 cooperation with UBE2D and UBE2L3 E2 ubiquitin-conjugating enzymes

  10. Results describe the crystal structure of a complex between the HECT domain of NEDD4L (show NEDD4L Proteins) and the E2 UbcH5B bearing a covalently linked Ub at its active site (UbcH5B approximately Ub).

Pig (Porcine) Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) interaction partners

Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) Protein Profile

Protein Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.

Alternative names and synonyms associated with Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2)

  • ubiquitin-conjugating enzyme E2D 2 (ube2d2)
  • zgc:77149 (zgc:77149)
  • ubiquitin-conjugating enzyme E2D 2 (UBE2D2)
  • ubiquitin-conjugating enzyme E2D 2 (Ube2d2)
  • ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) (ube2d2l)
  • ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) (ube2d2)
  • ubiquitin-conjugating enzyme E2D 2A (Ube2d2a)
  • ubiquitin-conjugating enzyme E2D 3 (ube2d3)
  • 1500034D03Rik protein
  • E2(17)KB2 protein
  • E217kB protein
  • PUBC1 protein
  • Ubc2e protein
  • ubc4 protein
  • UBC4/5 protein
  • UBCH5B protein
  • Ube2d2 protein
  • ube2d3.1 protein
  • wu:fj13d01 protein
  • xubc4 protein
  • zgc:55886 protein
  • zgc:73200 protein

Protein level used designations for UBE2D2

ubiquitin-conjugating enzyme E2D 2 , ubiquitin-conjugating enzyme E2 D2 , p53-regulated ubiquitin-conjugating enzyme 1 , ubiquitin carrier protein D2 , ubiquitin-conjugating enzyme E2-17 kDa 2 , ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5) , ubiquitin-protein ligase D2 , E2(17)KB 2 , ubc2e ubiquitin conjugating enzyme , ubiquitin-conjugating enzyme E2(17)KB 2 , ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) , UB2D2 , ubiquitin-conjugating enzyme E2 D3 , ubiquitin conjugating enzyme 2e , ubiquitin carrier protein 4 , ubiquitin conjugating enzyme E2 , ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog)

100194508 Salmo salar
393934 Danio rerio
7322 Homo sapiens
641452 Rattus norvegicus
416137 Gallus gallus
612742 Canis lupus familiaris
780418 Sus scrofa
541003 Bos taurus
335444 Danio rerio
446340 Xenopus laevis
56550 Mus musculus
403384 Xenopus laevis
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