UBE2D2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all UBE2D2 Proteins
- UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This UBE2D2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human UBE2D2 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product UBE2D2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
- Alternative Name
- Ube2d2 (UBE2D2 Products)
- Synonyms
- E2(17)KB2 Protein, PUBC1 Protein, UBC4 Protein, UBC4/5 Protein, UBCH5B Protein, 1500034D03Rik Protein, Ubc2e Protein, Ube2d2 Protein, ubc4 Protein, ube2d2 Protein, zgc:55886 Protein, E217kB Protein, ubiquitin conjugating enzyme E2 D2 Protein, ubiquitin-conjugating enzyme E2D 2A Protein, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) Protein, ubiquitin-conjugating enzyme E2D 2 Protein, ubiquitin conjugating enzyme E2 D3 Protein, UBE2D2 Protein, Ube2d2a Protein, ube2d2 Protein, Ube2d2 Protein, UBE2D3 Protein
- Background
- Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene.
- Molecular Weight
- 16.6 kDa
- NCBI Accession
- NP_003330
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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