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Browse our ELAVL1 Proteins (ELAVL1)

Full name:
ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) Proteins (ELAVL1)
On www.antibodies-online.com are 6 ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1) Proteins from 4 different suppliers available. Additionally we are shipping ELAVL1 Antibodies (88) and ELAVL1 Kits (7) and many more products for this protein. A total of 108 ELAVL1 products are currently listed.
Synonyms:
2410055N02Rik, ELAV1, elra, fa25f08, fb59a02, fc60g02, hua, HuR, MelG, W91709, wu:fa25f08, wu:fb59a02, wu:fc60g02, zHuA
list all proteins Gene Name GeneID UniProt
ELAVL1 1994 Q15717
Rat ELAVL1 ELAVL1 363854  
ELAVL1 15568 P70372

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ELAVL1 Proteins (ELAVL1) by Origin

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More Proteins for ELAVL1 Interaction Partners

Human ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1) interaction partners

  1. HuR binds to the pyrimidine-rich sequence and antagonize its effect in regulating WT1 (show WT1 Proteins) +/-KTS isoforms.

  2. High HUR expression is associated with Thyroid cancer.

  3. Results indicate that HuR induces 14-3-3zeta (show YWHAZ Proteins) translation via interaction with its 3' UTR and that 14-3-3zeta (show YWHAZ Proteins) is necessary for stimulation of intestinal epithelial cell migration after wounding.

  4. HuR blocks miR (show MLXIP Proteins)-675 processing from H19 (show NCKAP1 Proteins) and prevents H19 (show NCKAP1 Proteins)-induced intestinal barrier barrier dysfunction.

  5. Unprecedentedly, HuR was also found to bind to miR (show MLXIP Proteins)-21 directly, preventing its interaction with the PDCD4 (show PDCD4 Proteins) 3'-UTR, thereby preventing the translation repression of PDCD4 (show PDCD4 Proteins).

  6. These results define a novel mechanism by which PKM2 regulates glioma cell growth, and also define a novel set of potential therapeutic targets along the PKM2-HuR-p27 (show PAK2 Proteins) pathway

  7. HuR regulates core biological processes, highlighting that HuR inhibition likely thwarts PDA viability through post-transcriptional regulation of diverse signaling pathways; it impairs malignant characteristics of pancreatic ductal adenocarcinoma cells

  8. miR-424 interacts with long non-coding RNA OIP5-AS1 and competes with HuR for binding to OIP5-AS1.

  9. HuR protein mediates resistance to carboplatin in ovarian cancer cells.

  10. Mesenchymal stromal cells inhibit Human antigen R (HuR) trascription, an enhancer of RENmRNA stability by IL10 (show IL10 Proteins) release

Cow (Bovine) ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1) interaction partners

  1. STAU1 (show STAU1 Proteins) & STAU2 (show STAU2 Proteins) & ELAVL1 mRNAs & proteins were detected throughout cow preimplantation development (show MTA2 Proteins) from the germinal vesicle (GV) oocyte to the blastocyst stage; ELAVL2 (show ELAVL2 Proteins) mRNAs were detectable from the GV to the morula stage; ELAVL2 (show ELAVL2 Proteins) protein was in all stages

Zebrafish ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1) interaction partners

  1. this study reveals a posttranscriptional regulatory mechanism by which RNA-binding protein (show RBM24 Proteins) Elavl1a regulates embryonic erythropoiesis by maintaining appropriate levels of gata1 (show GATA1 Proteins) expression.

Mouse (Murine) ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1) interaction partners

  1. Results indicate that HuR induces 14-3-3zeta (show YWHAZ Proteins) translation via interaction with its 3' UTR and that 14-3-3zeta (show YWHAZ Proteins) is necessary for stimulation of intestinal epithelial cell migration after wounding.

  2. Knockdown of endogenous HuR protein abrogates the IL-1beta-mediated increase in xCT mRNA half-life.

  3. The current data suggested that miR (show MLXIP Proteins)-291b-3p contributed to NCTC1469 cell apoptosis by regulating the expression of HuR, which in turn increased Bcl-2 (show BCL2 Proteins) stability.

  4. HuR may regulate genes in multiple canonical pathways involved in T cell activation especially the CD28 (show CD28 Proteins) family signaling pathway.

  5. HuR acts as a specialized controller of oxidative metabolism in neurons to confer protection from neurodegeneration.

  6. We show that denervation increases expression of the RNA-binding protein HuR, which in turn, causes an increase in the stability of AChR beta (show CHRNB1 Proteins)-subunit (show POLG Proteins) mRNAs in denervated muscle.

  7. HuR is essential for normal mucosal growth in the small intestine by altering Wnt (show WNT2 Proteins) signals through up-regulation of LRP6 (show LRP6 Proteins) expression.

  8. HuR does not play a role in APA (show ENPEP Proteins) of the Hsp70.3 (show HSPA1A Proteins) mRNA, and these two regulatory events appear to be mutually exclusive regulators of Hsp70.3 (show HSPA1A Proteins) expression

  9. ELAVL1 antagonized binding of miR (show MLXIP Proteins)-27 to the 3' UTR of Zfp36 (show ZFP36 Proteins) mRNA and alleviated miR (show MLXIP Proteins)-27-mediated suppression of ZFP36 (show ZFP36 Proteins).

  10. Data suggest that p38 MAP kinase (show MAPK14 Proteins) regulates c-fos/cellular oncogene fos mRNA stability/decay by affecting state of phosphorylation of Elavl1/HuR (Hu antigen R).

ELAVL1 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.

Alternative names and synonyms associated with ELAVL1

  • ELAV-like protein 1 (elav1)
  • ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1)
  • ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (Elavl1)
  • ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (elavl1)
  • ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R) (Elavl1)
  • 2410055N02Rik protein
  • ELAV1 protein
  • elra protein
  • fa25f08 protein
  • fb59a02 protein
  • fc60g02 protein
  • hua protein
  • HuR protein
  • MelG protein
  • W91709 protein
  • wu:fa25f08 protein
  • wu:fb59a02 protein
  • wu:fc60g02 protein
  • zHuA protein

Protein level used designations for ELAVL1

ELAV-like protein 1 , Hu antigen R , embryonic lethal, abnormal vision, drosophila, homolog-like 1 , hu-antigen R , ELAV like 1 , ELAV-like 1 (Hu antigen R) , elav-related A , embryonic lethal, abnormal vision-related A , etID309757.2 , ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) , HU-antigen A , elav-like generic protein , melG

GENE ID SPECIES
100301835 Oncorhynchus mykiss
1994 Homo sapiens
363854 Rattus norvegicus
617316 Bos taurus
30736 Danio rerio
15568 Mus musculus
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