You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our anti-PRKAA1 (PRKAA1) Antibodies

Full name:
anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit Antibodies (PRKAA1)
On www.antibodies-online.com are 268 Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) Antibodies from 27 different suppliers available. Additionally we are shipping PRKAA1 Kits (20) and PRKAA1 Proteins (6) and many more products for this protein. A total of 303 PRKAA1 products are currently listed.
Synonyms:
AI194361, AI450832, AL024255, AMPK, AMPK1, AMPKa1, AMPKalpha1, C130083N04Rik, cb116, im:7154392, PRKAA1, sb:cb130, wu:fa94c10
list all antibodies Gene Name GeneID UniProt
PRKAA1 108080  
PRKAA1 5562 Q13131
PRKAA1 65248 P54645

Show all species

Show all synonyms

Most Popular Reactivities for anti-PRKAA1 (PRKAA1) Antibodies

Select your species and application

anti-Mouse (Murine) PRKAA1 Antibodies:

anti-Human PRKAA1 Antibodies:

anti-Rat (Rattus) PRKAA1 Antibodies:

All available anti-PRKAA1 Antibodies

Go to our pre-filtered search.

Top referenced anti-PRKAA1 Antibodies

  1. Cow (Bovine) Polyclonal PRKAA1 Primary Antibody for ICC, IF - ABIN151706 : Zang, Zuccollo, Hou, Nagata, Walsh, Herscovitz, Brecher, Ruderman, Cohen: AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells. in The Journal of biological chemistry 2004 (PubMed)
    Show all 12 references for ABIN151706

  2. Human Monoclonal PRKAA1 Primary Antibody for IF, WB - ABIN393792 : Jassim, Fernø, Theisen, Haberhausen, Christoforou, Håvik, Gebhardt, Remschmidt, Mehler-Wex, Hebebrand, Lehellard, Steen: Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia. in Pharmacopsychiatry 2011 (PubMed)
    Show all 5 references for ABIN393792

  3. Human Polyclonal PRKAA1 Primary Antibody for IF, IHC (p) - ABIN197410 : Nielsen, Mustard, Graham, Yu, MacDonald, Pilegaard, Goodyear, Hardie, Richter, Wojtaszewski: 5'-AMP-activated protein kinase activity and subunit expression in exercise-trained human skeletal muscle. in Journal of applied physiology (Bethesda, Md. : 1985) 2003 (PubMed)
    Show all 4 references for ABIN197410

  4. Human Polyclonal PRKAA1 Primary Antibody for IHC (p), WB - ABIN359481 : Pang, Xiong, Li, Qiu, Jin, Shen, Li: Conserved alpha-helix acts as autoinhibitory sequence in AMP-activated protein kinase alpha subunits. in The Journal of biological chemistry 2007 (PubMed)
    Show all 3 references for ABIN359481

  5. Human Polyclonal PRKAA1 Primary Antibody for IHC (p) - ABIN197320 : Kim, Tannenbaum, White: Global phosphoproteome of HT-29 human colon adenocarcinoma cells. in Journal of proteome research 2005 (PubMed)
    Show all 2 references for ABIN197320

  6. Human Polyclonal PRKAA1 Primary Antibody for EIA, WB - ABIN359393 : Zhang, Ye, Wu, Ren, Zhao, Zhao, Fu, Shen, Fan, Lu, Zhong, Xu, Han, Zhang, Tao, Huang, Zhou, Hu, Gu, Chen, Chen: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. in Genome research 2000 (PubMed)
    Show all 2 references for ABIN359393

  7. Chicken Polyclonal PRKAA1 Primary Antibody for WB - ABIN2785500 : Hasumi, Baba, Hong, Hasumi, Huang, Yao, Valera, Linehan, Schmidt: Identification and characterization of a novel folliculin-interacting protein FNIP2. in Gene 2008 (PubMed)

  8. Human Polyclonal PRKAA1 Primary Antibody for FACS, IHC (p) - ABIN652306 : Puissant, Robert, Fenouille, Luciano, Cassuto, Raynaud, Auberger: Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation. in Cancer research 2010 (PubMed)

More Antibodies against PRKAA1 Interaction Partners

Mouse (Murine) Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. m(6)A methylation status influences RNA, AMPKalpha1 phosphorylation and dysfunctional adipose tissue induced by high-fat diet

  2. phosphorylation of PLIN2 (show PLIN2 Antibodies) is dependent on AMPK and occurs after the interaction of PLIN2 (show PLIN2 Antibodies) with the chaperone-mediated autophagy chaperone HSPA8/Hsc70 (show HSPA8 Antibodies).

  3. Ngb (show NGB Antibodies) functions as a metabolic regulator and enhances cellular anabolism through the inhibition of AMPK signaling.

  4. findings indicate that miR (show MLXIP Antibodies)-291b-3p promotes hepatic lipogenesis by suppressing AMPKalpha1 expression and activity, indicating the therapeutic potential of miR (show MLXIP Antibodies)-291b-3p inhibitors in fatty liver disease.

  5. Adiponectin abrogated these effects. From a mechanistic standpoint, the effects of adiponectin on MP release and molecular signaling occurred at least in part through the AMPK, Akt and NFkappaB pathways.

  6. The authors unexpectedly uncover a ROQUIN (show RC3H1 Antibodies)-AMPK metabolic signaling nexus essential for selectively promoting T follicular helper cell responses.

  7. Rapid activation of AMPK was detected after exposure of cortical neuronal cultures to zinc, which was induced by LKB1 (show STK11 Antibodies) activation but not increased intracellular AMP (show TMPRSS5 Antibodies) levels or CaMKKbeta activation.

  8. PDE4B (show PDE4B Antibodies) phosphorylated by AMPK at Ser304 is important for activation.

  9. Deletion of the AMPK alpha-subunits improves oral but not intraperitoneal glucose tolerance.

  10. The results indicate that AMPK is a negative regulator of Ccr2 (show CCR2 Antibodies) expression in RAW264.7 macrophages, and that the mechanism of action of AMPK inhibition of Ccr2 (show CCR2 Antibodies) is mediated, in part, through the NF-kappaB (show NFKB1 Antibodies) pathway.

Cow (Bovine) Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. Endometrial inflammatory responses to lipopolysaccharide were also reduced by small molecules that activate or inhibit the intracellular sensor of energy, AMP-activated protein kinase (AMPK (show PRKAA2 Antibodies)).

  2. The results suggest that activation of AMPK represses global protein synthesis in mammary epithelial cells through inhibition of mTORC1 signaling.

  3. Nitrated oleic acid activates AMPK in endothelial cells.

  4. Findings suggest that ischemic factor stimulation of the blood brain barrier Na-K-Cl cotransporter (show SLC12A1 Antibodies) involves activation of AMPK.

  5. Results suggest that mitochondria-derived superoxide anions and peroxynitrite are required for Berberine-induced AMPK activation in endothelial cells.

  6. the expression, but not the kinase activity, of AMPK and CaMKKbeta is necessary for ADP signaling to eNOS (show NOS3 Antibodies)

Human Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. Down-regulation of miR (show MLXIP Antibodies)-137 ameliorates high glucose-induced injury in HUVEC cells by overexpression of AMPKa1, leading to increasing cellular reductive reactions and decreasing oxidative stress.

  2. human cells were infected with lentiviruses expressing shRNA targeting both alpha1 and alpha2 AMPK subunits. AMPK activation inhibits Gli1 (show GLI1 Antibodies)-driven proliferation and that this effect is linked to Ser408 phosphorylation, which represents a key metabolic checkpoint for Hh signaling.

  3. AMPK actions extend well beyond its energy-regulating role, and it appears to possess an essential role in regulating fibrosis of the myocardium. (Review)

  4. when treated with exendin-4 plus AICAR (show ATIC Antibodies), an AMPK activator, cell apoptosis increased with higher ratio of phosphorylayed-AMPK/AMPK, lower ratio of phosphorylated-mTOR/mTOR (show FRAP1 Antibodies) and higher expression of cleaved caspase-3 (show CASP3 Antibodies) than those in exendin-4 alone group

  5. binding between AMPK and b-catenin occurs in the cytosolic fraction, and therefore concluded that the cancer cell antiproliferative effects of selenium are mediated by a GSK3b-independent AMPK/b-catenin pathway

  6. The protective effect of ampelopsin against hyperglycemia-induced cell damage, which functions by targeting autophagy via AMPK activation, makes it a promising pharmacological treatment for type-2 diabetes.

  7. Metformin inhibits PGE2-induced CYP19A1 (show CYP19A1 Antibodies) mRNA expression/aromatase (show CYP19A1 Antibodies) activity via AMPK activation in endometriotic stromal cells.

  8. these results indicated that the C allele of PRKAA1 rs13361707 was a low-penetrate risk factor for gastric cancer

  9. our findings suggest that EEKS inhibits the growth of HepG2 cells by inducing AMPK-mediated caspase (show CASP3 Antibodies)-dependent apoptosis, suggesting the potential therapeutic application of EEKS in the treatment or prevention of cancers.

  10. Data show CGK733 induced microtubule associated protein LC3B (show MAP1LC3B Antibodies) formation upstream of AMP-activated protein kinase (show PRKAA2 Antibodies) and protein kinase (show CDK7 Antibodies) RNA-like endoplasmic reticulum kinase/CCAAT-enhancer-binding protein homologous protein (show DDIT3 Antibodies) pathways and p21 Cip1 (show CDKN1A Antibodies) expression.

Zebrafish Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. AMPK-related pathways may be compromised during fluoxetine exposure as a result of increased miRNA abundance.

Xenopus laevis Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. Constitutively active AMPKgammaR70Q significantly decreases Napi-IIa (show SLC34A1 Antibodies) oocyte cell membrane abundance, an effect not mimicked by catalytically-inactive AMPKalphaK45R.

  2. NDPK-A (show NME1 Antibodies) exists in a functional cellular complex with AMPK (show PRKAA2 Antibodies) and CFTR (show CFTR Antibodies) in airway epithelia, and NDPK-A (show NME1 Antibodies) catalytic function is required for the AMPK (show PRKAA2 Antibodies)-dependent regulation of CFTR (show CFTR Antibodies)

Pig (Porcine) Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. AMPK-mTOR (show FRAP1 Antibodies)-autophagy signaling is altered by intrauterine growth restriction in newborn piglets.

  2. Data indicate that 17beta-estradiol reduced Sertoli Cell proliferation by inhibiting microRNA miR (show MYLIP Antibodies)-1285 and thus activating AMP-activated protein kinase (AMPK (show PRKAA2 Antibodies)).

  3. L-Glutamine (show GFPT2 Antibodies) enhances enterocyte growth but did not affect abundances of total or phosphorylated AMPK protein.

  4. AMPK activity plays an important role in the maintenance of the spermatozoa quality during long-term storage of boar semen.

  5. AMPK, lying downstream of PKA, regulates at different levels mammalian spermatozoa membrane function.

  6. Porcine circovirus type 2 (PCV2) might induce autophagy via the AMPK/ERK (show MAPK1 Antibodies)/TSC2 (show TSC2 Antibodies)/mTOR (show FRAP1 Antibodies) signaling pathway in the host cells, representing a pivotal mechanism for PCV2 pathogenesis

  7. AMPK deficiency or inhibition attenuated or mitigated ethanol exposure-triggered glucose intolerance and compromised cardiac contraction by increased phosphorylation of AMPK and acetyl-CoA carboxylase as well as autophagosome accumulation.

  8. AMPK functions to inhibit IGF-I (show IGF1 Antibodies)-stimulated PI3K pathway activation through stimulation of IRS-1 (show IRS1 Antibodies) serine 794 phosphorylation.

  9. acute activation of AMPK increases intestinal glucose absorption after administration of long-chain n-3 polyunsaturated fatty acids during gestation

PRKAA1 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Alternative names and synonyms associated with PRKAA1

  • protein kinase, AMP-activated, alpha 3 catalytic subunit (Prkaa3) antibody
  • protein kinase, AMP-activated, alpha 1 catalytic subunit (PRKAA1) antibody
  • protein kinase, AMP-activated, alpha 1 catalytic subunit (prkaa1) antibody
  • protein kinase, AMP-activated, alpha 1 catalytic subunit (Prkaa1) antibody
  • AI194361 antibody
  • AI450832 antibody
  • AL024255 antibody
  • AMPK antibody
  • AMPK1 antibody
  • AMPKa1 antibody
  • AMPKalpha1 antibody
  • C130083N04Rik antibody
  • cb116 antibody
  • im:7154392 antibody
  • PRKAA1 antibody
  • sb:cb130 antibody
  • wu:fa94c10 antibody

Protein level used designations for PRKAA1

protein kinase, AMP-activated, alpha 3 catalytic subunit , protein kinase, AMP-activated, alpha 1 catalytic subunit , 5'-AMP-activated protein kinase catalyti subunit alpha-1-like protein , 5'-AMP-activated protein kinase catalytic subunit alpha-1 , AMPK-activated protein kinase alpha-1 subunit , 5'-AMP-activated protein kinase alpha 1 catalytic subunit , 5'-AMP-activated protein kinase, catalytic alpha-1 chain , ACACA kinase , AMP -activate kinase alpha 1 subunit , AMP-activated protein kinase, catalytic, alpha-1 , AMPK alpha 1 , AMPK subunit alpha-1 , HMGCR kinase , acetyl-CoA carboxylase kinase , hydroxymethylglutaryl-CoA reductase kinase , tau-protein kinase PRKAA1 , AMPK alpha-1 chain , AMP-activated protein kinase, alpha 1 catalytic subunit , ampka1 , 5'-AMP-activated protein kinase alpha-1 catalytic subunit , AMPKalpha1 , 63 kDa subunit , AMPK 63 kDa subunit

GENE ID SPECIES
108080 Mus musculus
100009710 Equus caballus
100034740 Meleagris gallopavo
100145520 Xenopus (Silurana) tropicalis
100294665 Ovis aries
540404 Bos taurus
5562 Homo sapiens
65248 Rattus norvegicus
105787 Mus musculus
100001198 Danio rerio
495290 Xenopus laevis
427185 Gallus gallus
479351 Canis lupus familiaris
100145903 Sus scrofa
100174304 Pongo abelii
Selected quality suppliers for anti-PRKAA1 (PRKAA1) Antibodies
Did you look for something else?