You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our anti-PRKAA1 (PRKAA1) Antibodies

Full name:
anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit Antibodies (PRKAA1)
On are 257 Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) Antibodies from 26 different suppliers available. Additionally we are shipping PRKAA1 Kits (28) and PRKAA1 Proteins (6) and many more products for this protein. A total of 300 PRKAA1 products are currently listed.
AI194361, AI450832, AL024255, AMPK, AMPK1, AMPKa1, AMPKalpha1, C130083N04Rik, cb116, im:7154392, PRKAA1, sb:cb130, wu:fa94c10
list all antibodies Gene Name GeneID UniProt
PRKAA1 108080  
PRKAA1 5562 Q13131
PRKAA1 65248 P54645

Show all species

Show all synonyms

Most Popular Reactivities for anti-PRKAA1 (PRKAA1) Antibodies

Select your species and application

anti-Mouse (Murine) PRKAA1 Antibodies:

anti-Human PRKAA1 Antibodies:

anti-Rat (Rattus) PRKAA1 Antibodies:

All available anti-PRKAA1 Antibodies

Go to our pre-filtered search.

Top referenced anti-PRKAA1 Antibodies

  1. Human Monoclonal PRKAA1 Primary Antibody for IF, WB - ABIN393792 : Jassim, Fernø, Theisen, Haberhausen, Christoforou, Håvik, Gebhardt, Remschmidt, Mehler-Wex, Hebebrand, Lehellard, Steen: Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia. in Pharmacopsychiatry 2011 (PubMed)
    Show all 5 references for ABIN393792

  2. Human Polyclonal PRKAA1 Primary Antibody for IF, IHC (p) - ABIN197410 : Nielsen, Mustard, Graham, Yu, MacDonald, Pilegaard, Goodyear, Hardie, Richter, Wojtaszewski: 5'-AMP-activated protein kinase activity and subunit expression in exercise-trained human skeletal muscle. in Journal of applied physiology (Bethesda, Md. : 1985) 2003 (PubMed)
    Show all 4 references for ABIN197410

  3. Human Polyclonal PRKAA1 Primary Antibody for IHC (p), WB - ABIN359481 : Pang, Xiong, Li, Qiu, Jin, Shen, Li: Conserved alpha-helix acts as autoinhibitory sequence in AMP-activated protein kinase alpha subunits. in The Journal of biological chemistry 2007 (PubMed)
    Show all 3 references for ABIN359481

  4. Human Polyclonal PRKAA1 Primary Antibody for IHC (p) - ABIN197320 : Kim, Tannenbaum, White: Global phosphoproteome of HT-29 human colon adenocarcinoma cells. in Journal of proteome research 2005 (PubMed)
    Show all 2 references for ABIN197320

  5. Human Polyclonal PRKAA1 Primary Antibody for EIA, WB - ABIN359393 : Zhang, Ye, Wu, Ren, Zhao, Zhao, Fu, Shen, Fan, Lu, Zhong, Xu, Han, Zhang, Tao, Huang, Zhou, Hu, Gu, Chen, Chen: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. in Genome research 2000 (PubMed)
    Show all 2 references for ABIN359393

  6. Human Polyclonal PRKAA1 Primary Antibody for IF, IHC (p) - ABIN196904 : Woods, Vertommen, Neumann, Turk, Bayliss, Schlattner, Wallimann, Carling, Rider: Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for ABIN196904

  7. Human Polyclonal PRKAA1 Primary Antibody for WB - ABIN2785614 : Hasumi, Baba, Hong, Hasumi, Huang, Yao, Valera, Linehan, Schmidt: Identification and characterization of a novel folliculin-interacting protein FNIP2. in Gene 2008 (PubMed)

  8. Human Polyclonal PRKAA1 Primary Antibody for FACS, IHC (p) - ABIN652306 : Puissant, Robert, Fenouille, Luciano, Cassuto, Raynaud, Auberger: Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation. in Cancer research 2010 (PubMed)

More Antibodies against PRKAA1 Interaction Partners

Mouse (Murine) Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. PDE4B (show PDE4B Antibodies) phosphorylated by AMPK at Ser304 is important for activation.

  2. Deletion of the AMPK alpha-subunits improves oral but not intraperitoneal glucose tolerance.

  3. The results indicate that AMPK is a negative regulator of Ccr2 (show CCR2 Antibodies) expression in RAW264.7 macrophages, and that the mechanism of action of AMPK inhibition of Ccr2 (show CCR2 Antibodies) is mediated, in part, through the NF-kappaB (show NFKB1 Antibodies) pathway.

  4. Data indicate that an AMP (show TMPRSS5 Antibodies)-ctivated kinase (AMPK)/cell-cycle inhibitor (show CDKN2A Antibodies) p27KIP1 (p27 (show CDKN1B Antibodies)) axis drives activation of autophagy in rapamycin-treated tuberous sclerosis 2 protein (Tsc2 (show TSC2 Antibodies))-null cells.

  5. The functional role of AMPKalpha1 in the development of the skeletal system and the pathogenesis of osteoarthritis

  6. AMP-activated protein kinase (AMPK (show PRKAA2 Antibodies)), a central metabolic regulator, plays critical roles in lineage specification

  7. BAIBA attenuates insulin (show INS Antibodies) resistance, suppresses inflammation and induces fatty acid oxidation via the AMPK-PPARdelta (show PPARD Antibodies) pathway in skeletal muscle

  8. These findings suggest that GSH deficiency triggers an AMPK-independent induction of autophagy in germ cells as an adaptive stress response.

  9. Data (including data from studies in knockout mice) suggest, as osteoblasts differentiate, early induction of AMPK in response to IGF-I (show IGF1 Antibodies)/IGFBP-2 (show IGFBP2 Antibodies) is followed by suppression of AMPK as required for osteogenesis; activation of AMPK stimulates autophagy.

  10. Data show that the transient receptor potential vanilloid type 1 (TRPV1 (show TRPV1 Antibodies)) ligand- induced increase in AMP-activated protein kinase (AMPK (show PRKAA2 Antibodies)) and nitric oxide synthase (show NOS Antibodies) type III (eNOS (show NOS3 Antibodies)) phosphorylation was markedly lower in TRPV1 (show TRPV1 Antibodies)-/- (knockout) than WT aortas.

Cow (Bovine) Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. Endometrial inflammatory responses to lipopolysaccharide were also reduced by small molecules that activate or inhibit the intracellular sensor of energy, AMP-activated protein kinase (AMPK (show PRKAA2 Antibodies)).

  2. The results suggest that activation of AMPK represses global protein synthesis in mammary epithelial cells through inhibition of mTORC1 signaling.

  3. Nitrated oleic acid activates AMPK in endothelial cells.

  4. Findings suggest that ischemic factor stimulation of the blood brain barrier Na-K-Cl cotransporter (show SLC12A1 Antibodies) involves activation of AMPK.

  5. Results suggest that mitochondria-derived superoxide anions and peroxynitrite are required for Berberine-induced AMPK activation in endothelial cells.

  6. the expression, but not the kinase activity, of AMPK and CaMKKbeta is necessary for ADP signaling to eNOS (show NOS3 Antibodies)

Human Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. our findings suggest that EEKS inhibits the growth of HepG2 cells by inducing AMPK-mediated caspase (show CASP3 Antibodies)-dependent apoptosis, suggesting the potential therapeutic application of EEKS in the treatment or prevention of cancers.

  2. Data show CGK733 induced microtubule associated protein LC3B (show MAP1LC3B Antibodies) formation upstream of AMP-activated protein kinase (show PRKAA2 Antibodies) and protein kinase (show CDK7 Antibodies) RNA-like endoplasmic reticulum kinase/CCAAT-enhancer-binding protein homologous protein (show DDIT3 Antibodies) pathways and p21 Cip1 (show CDKN1A Antibodies) expression.

  3. Data suggest that nitroxoline induces anticancer activity through AMP (show APRT Antibodies)-activated kinase (AMPK)/mTOR (show FRAP1 Antibodies) serine-threonine kinase (show TLK2 Antibodies) (mTOR (show FRAP1 Antibodies)) signaling pathway via checkpoint kinase 2 (Chk2 (show CHEK2 Antibodies)) activation.

  4. Mutation of Fyn (show FYN Antibodies) phosphorylation sites on PIKE (show AGAP2 Antibodies)-A, depletion of Fyn (show FYN Antibodies), or pharmacological inhibition of Fyn (show FYN Antibodies) blunts the association between PIKE (show AGAP2 Antibodies)-A and AMPK, resulting in loss of its inhibitory effect on AMPK. regulates AMPK activity in cancers.

  5. Functional characterization revealed an undescribed role for AMPK-dependent phosphorylation of AKAP1 (show AKAP1 Antibodies) in mitochondrial respiration.

  6. AMPK phosphorylation of the RHOA (show RHOA Antibodies) guanine nucleotide exchange factor (show RASGRF1 Antibodies) NET1A (show NET1 Antibodies) inhibits extracellular matrix degradation, an early step in cell invasion

  7. Data indicate that long non-coding RNAs (lncRNAs) NBR2 (neighbour of BRCA1 gene 2) interacts with AMP (show APRT Antibodies)-activated kinase (AMPK) and promotes AMPK kinase activity during energy stress.

  8. This review focuses on the function of the LKB1 (show STK11 Antibodies)/AMPK pathway in the invasion and migration of cancer cells and provides an overview of therapeutic strategies aimed at this pathway in malignant tumors.

  9. Data show that voltage-dependent anion channel 1 (VDAC1 (show VDAC1 Antibodies)) knockout cells are resistant to AMP-activated protein kinase (AMPK (show PRKAA2 Antibodies)) and mechanistic target of rapamycin (mTOR (show FRAP1 Antibodies)) modulation by itraconazole, indicating VDAC1 (show VDAC1 Antibodies) is the mediator of the activity.

  10. These results suggest that the antitumor effects of paclitaxel in breast cancer are mediated by activation of the AMPK/EF1alpha/FOXO3a (show FOXO3 Antibodies) signaling pathway.

Zebrafish Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. AMPK-related pathways may be compromised during fluoxetine exposure as a result of increased miRNA abundance.

Xenopus laevis Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. Constitutively active AMPKgammaR70Q significantly decreases Napi-IIa (show SLC34A1 Antibodies) oocyte cell membrane abundance, an effect not mimicked by catalytically-inactive AMPKalphaK45R.

  2. NDPK-A (show NME1 Antibodies) exists in a functional cellular complex with AMPK (show PRKAA2 Antibodies) and CFTR (show CFTR Antibodies) in airway epithelia, and NDPK-A (show NME1 Antibodies) catalytic function is required for the AMPK (show PRKAA2 Antibodies)-dependent regulation of CFTR (show CFTR Antibodies)

Pig (Porcine) Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. Data indicate that 17beta-estradiol reduced Sertoli Cell proliferation by inhibiting microRNA miR (show MYLIP Antibodies)-1285 and thus activating AMP-activated protein kinase (AMPK (show PRKAA2 Antibodies)).

  2. L-Glutamine (show GFPT2 Antibodies) enhances enterocyte growth but did not affect abundances of total or phosphorylated AMPK protein.

  3. AMPK activity plays an important role in the maintenance of the spermatozoa quality during long-term storage of boar semen.

  4. AMPK, lying downstream of PKA, regulates at different levels mammalian spermatozoa membrane function.

  5. Porcine circovirus type 2 (PCV2) might induce autophagy via the AMPK/ERK (show MAPK1 Antibodies)/TSC2 (show TSC2 Antibodies)/mTOR (show FRAP1 Antibodies) signaling pathway in the host cells, representing a pivotal mechanism for PCV2 pathogenesis

  6. AMPK deficiency or inhibition attenuated or mitigated ethanol exposure-triggered glucose intolerance and compromised cardiac contraction by increased phosphorylation of AMPK and acetyl-CoA carboxylase as well as autophagosome accumulation.

  7. AMPK functions to inhibit IGF-I (show IGF1 Antibodies)-stimulated PI3K pathway activation through stimulation of IRS-1 (show IRS1 Antibodies) serine 794 phosphorylation.

  8. acute activation of AMPK increases intestinal glucose absorption after administration of long-chain n-3 polyunsaturated fatty acids during gestation

PRKAA1 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Alternative names and synonyms associated with PRKAA1

  • protein kinase, AMP-activated, alpha 3 catalytic subunit (Prkaa3) antibody
  • protein kinase, AMP-activated, alpha 1 catalytic subunit (PRKAA1) antibody
  • protein kinase, AMP-activated, alpha 1 catalytic subunit (prkaa1) antibody
  • protein kinase, AMP-activated, alpha 1 catalytic subunit (Prkaa1) antibody
  • AI194361 antibody
  • AI450832 antibody
  • AL024255 antibody
  • AMPK antibody
  • AMPK1 antibody
  • AMPKa1 antibody
  • AMPKalpha1 antibody
  • C130083N04Rik antibody
  • cb116 antibody
  • im:7154392 antibody
  • PRKAA1 antibody
  • sb:cb130 antibody
  • wu:fa94c10 antibody

Protein level used designations for PRKAA1

protein kinase, AMP-activated, alpha 3 catalytic subunit , protein kinase, AMP-activated, alpha 1 catalytic subunit , 5'-AMP-activated protein kinase catalyti subunit alpha-1-like protein , 5'-AMP-activated protein kinase catalytic subunit alpha-1 , AMPK-activated protein kinase alpha-1 subunit , 5'-AMP-activated protein kinase alpha 1 catalytic subunit , 5'-AMP-activated protein kinase, catalytic alpha-1 chain , ACACA kinase , AMP -activate kinase alpha 1 subunit , AMP-activated protein kinase, catalytic, alpha-1 , AMPK alpha 1 , AMPK subunit alpha-1 , HMGCR kinase , acetyl-CoA carboxylase kinase , hydroxymethylglutaryl-CoA reductase kinase , tau-protein kinase PRKAA1 , AMPK alpha-1 chain , AMP-activated protein kinase, alpha 1 catalytic subunit , ampka1 , 5'-AMP-activated protein kinase alpha-1 catalytic subunit , AMPKalpha1 , 63 kDa subunit , AMPK 63 kDa subunit

108080 Mus musculus
100009710 Equus caballus
100034740 Meleagris gallopavo
100145520 Xenopus (Silurana) tropicalis
100294665 Ovis aries
540404 Bos taurus
5562 Homo sapiens
65248 Rattus norvegicus
105787 Mus musculus
100001198 Danio rerio
495290 Xenopus laevis
427185 Gallus gallus
479351 Canis lupus familiaris
100145903 Sus scrofa
100174304 Pongo abelii
Selected quality suppliers for anti-PRKAA1 (PRKAA1) Antibodies
Did you look for something else?