Browse our anti-PRKAA1 (PRKAA1) Antibodies

Full name:
anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit Antibodies (PRKAA1)
On www.antibodies-online.com are 310 Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) Antibodies from 30 different suppliers available. Additionally we are shipping PRKAA1 Kits (19) and PRKAA1 Proteins (6) and many more products for this protein. A total of 344 PRKAA1 products are currently listed.
Synonyms:
AI194361, AI450832, AL024255, AMPK, AMPK1, AMPKa1, AMPKalpha1, C130083N04Rik, cb116, im:7154392, PRKAA1, sb:cb130, wu:fa94c10
list all antibodies Gene Name GeneID UniProt
PRKAA1 108080  
PRKAA1 5562 Q13131
PRKAA1 65248 P54645

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Top referenced anti-PRKAA1 Antibodies

  1. Cow (Bovine) Polyclonal PRKAA1 Primary Antibody for ICC, IF - ABIN151706 : Zang, Zuccollo, Hou, Nagata, Walsh, Herscovitz, Brecher, Ruderman, Cohen: AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells. in The Journal of biological chemistry 2004 (PubMed)
    Show all 12 references for 151706

  2. Human Monoclonal PRKAA1 Primary Antibody for IF, WB - ABIN393792 : Jassim, Fernø, Theisen, Haberhausen, Christoforou, Håvik, Gebhardt, Remschmidt, Mehler-Wex, Hebebrand, Lehellard, Steen: Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia. in Pharmacopsychiatry 2011 (PubMed)
    Show all 5 references for 393792

  3. Human Polyclonal PRKAA1 Primary Antibody for IHC (p), WB - ABIN359481 : Pang, Xiong, Li, Qiu, Jin, Shen, Li: Conserved alpha-helix acts as autoinhibitory sequence in AMP-activated protein kinase alpha subunits. in The Journal of biological chemistry 2007 (PubMed)
    Show all 3 references for 359481

  4. Human Polyclonal PRKAA1 Primary Antibody for EIA, WB - ABIN359393 : Zhang, Ye, Wu, Ren, Zhao, Zhao, Fu, Shen, Fan, Lu, Zhong, Xu, Han, Zhang, Tao, Huang, Zhou, Hu, Gu, Chen, Chen: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. in Genome research 2000 (PubMed)
    Show all 2 references for 359393

  5. Human Polyclonal PRKAA1 Primary Antibody for IF, IHC (p) - ABIN196904 : Kim, Tannenbaum, White: Global phosphoproteome of HT-29 human colon adenocarcinoma cells. in Journal of proteome research 2005 (PubMed)
    Show all 2 references for 196904

  6. Human Monoclonal PRKAA1 Primary Antibody for ELISA, FACS - ABIN4280435 : Xiao, Kwong, Daemen, Belvin, Liang, Hatzivassiliou, OBrien: Metabolic Response to NAD Depletion across Cell Lines Is Highly Variable. in PLoS ONE 2016 (PubMed)
    Show all 2 references for 4280435

  7. Cow (Bovine) Polyclonal PRKAA1 Primary Antibody for WB - ABIN2785500 : Hasumi, Baba, Hong, Hasumi, Huang, Yao, Valera, Linehan, Schmidt: Identification and characterization of a novel folliculin-interacting protein FNIP2. in Gene 2008 (PubMed)

  8. Human Polyclonal PRKAA1 Primary Antibody for FACS, IHC (p) - ABIN652306 : Puissant, Robert, Fenouille, Luciano, Cassuto, Raynaud, Auberger: Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation. in Cancer research 2010 (PubMed)

More Antibodies against PRKAA1 Interaction Partners

Mouse (Murine) Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. mitochondrial dysfunction triggers LKB1 (show STK11 Antibodies)-mediated AMPK activation, which stimulates Sirt2 (show SIRT2 Antibodies) phosphorylation, leading to activation of mTOR (show FRAP1 Antibodies)-RAPTOR (show RPTOR Antibodies) and Glut1 (show SLC2A1 Antibodies)-mediated glucose uptake.

  2. AMPK-dependent metabolic repair mechanisms are important for mitigating lung injury.

  3. these data demonstrated that LKB1 (show STK11 Antibodies)/AMPK signaling pathway activation improved the survival of diabetic mice complicated with endotoxemia. Thus, LKB1 (show STK11 Antibodies)/AMPK signaling pathway may serve as a potentially useful therapeutic target for severe infection in diabetic patients.

  4. We confirmed that procyanidins suppressed acute hyperglycemia with an oral glucose tolerance test in a dose-dependent manner.procyanidins, especially cinnamtannin A2, significantly ameliorate postprandial hyperglycemia at least in part by promoting GLUT4 (show SLC2A4 Antibodies) translocation to the plasma membrane by activating both insulin (show INS Antibodies)- and AMPK-signaling pathways.

  5. These findings demonstrate that the AMPK-TBC1D1 (show TBC1D1 Antibodies) signaling nexus interacts with the PKB (show AKT2 Antibodies)-mTOR (show FRAP1 Antibodies) pathway via IGF1 (show IGF1 Antibodies) secretion, which consequently controls expression of lipogenic genes in the adipose tissue

  6. AMPKa1 deficiency impairs autophagy-mediated monocyte differentiation and decreases monocyte/macrophage survival

  7. The authors identified lactate dehydrogenase (LDH) as a new functional target of AMPKalpha1.

  8. AMPKalpha1 knockout (KO) mice exhibit normal renal sodium handling and a moderate antidiuretic state. This is accompanied by higher urinary aldosterone excretion rates and reduced blood pressure. Plasma volume, however, was found to be increased compared with wild-type mice.

  9. the cellular levels of alpha-ketoglutarate (alphaKG), a key metabolite required for TET-mediated DNA demethylation, were profoundly increased and required for active DNA demethylation of the Prdm16 (show PRDM16 Antibodies) promoter.

  10. AMPK in adipocytes is vital for maintaining mitochondrial integrity.

Cow (Bovine) Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. Endometrial inflammatory responses to lipopolysaccharide were also reduced by small molecules that activate or inhibit the intracellular sensor of energy, AMP-activated protein kinase (AMPK (show PRKAA2 Antibodies)).

  2. The results suggest that activation of AMPK represses global protein synthesis in mammary epithelial cells through inhibition of mTORC1 signaling.

  3. Nitrated oleic acid activates AMPK in endothelial cells.

  4. Findings suggest that ischemic factor stimulation of the blood brain barrier Na-K-Cl cotransporter (show SLC12A1 Antibodies) involves activation of AMPK.

  5. Results suggest that mitochondria-derived superoxide anions and peroxynitrite are required for Berberine-induced AMPK activation in endothelial cells.

  6. the expression, but not the kinase activity, of AMPK and CaMKKbeta is necessary for ADP signaling to eNOS (show NOS3 Antibodies)

Human Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. Data indicate that siRNA-mediated knockdown of AMP-activated protein kinase (show PRKAA2 Antibodies) alpha (show PAK1 Antibodies) subunit (show POLG Antibodies) AMPKalpha1 inhibited icaritin-induced autophagy activation, but exacerbated colorectal cancer (CRC (show CALR Antibodies)) cell death.

  2. Retinoid-related orphan receptor alpha (RORalpha) reduction occurs in gastric cancer leading to the survival of tumor cells, which is attenuated by AMP-activated protein kinase (AMPK (show PRKAA2 Antibodies)), therefore, both RORalpha and AMPK are potential targets for the intervention and therapy in gastric carcinoma.

  3. BCLB (show BCL2L10 Antibodies) expression was a starvation stress sensor inducing apoptosis and autophagy simultaneously in HCC (show FAM126A Antibodies) cells through the adenosine monophosphate-activated protein kinase AMPK (show GRK4 Antibodies)-mTOR (show FRAP1 Antibodies) signaling cascade.

  4. findings show that dengue virus ( DENV) infection activates and requires the central metabolic regulator AMPK for its replication and the induction of lipophagy. This is required for the induction of lipophagy, but not basal autophagy, in DENV-infected cells

  5. PRKAA1 polymorphisms may contribute to the susceptibility of chronic HBV infection in Chinese Han origin.

  6. the role of AMPK activation in controlling beige (show LYST Antibodies) differentiation is restricted to morphological features, but not to actual metabolic changes.

  7. these results demonstrate the effective anti-autophagic of NRAGE (show MAGED1 Antibodies) in non-small-cell lung cancer cells through AMPK/Ulk1 (show ULK1 Antibodies)/Atg13 (show ATG13 Antibodies) autophagy signaling pathways. Therefore, NRAGE (show MAGED1 Antibodies) could be used as a potential therapeutic target for lung cancer.

  8. AMPKa1 deficiency impairs autophagy-mediated monocyte differentiation and decreases monocyte/macrophage survival

  9. Activation of AMPK/mTOR (show FRAP1 Antibodies) signaling protected primary proximal tubular cells (PTCs) from high glucose-induced epithelial-mesenchymal transition (EMT (show ITK Antibodies)) and cellular senescence.

  10. Such effect by miR (show MLXIP Antibodies)-429 was again abolished with AMPKalpha1 silence or mutation. Together, we propose that PP2A (show PPP2R4 Antibodies)-c silence by miR (show MLXIP Antibodies)-429 activates AMPK and protects osteoblastic cells from Dex.

Zebrafish Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. AMPK-related pathways may be compromised during fluoxetine exposure as a result of increased miRNA abundance.

Xenopus laevis Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. Constitutively active AMPKgammaR70Q significantly decreases Napi-IIa (show SLC34A1 Antibodies) oocyte cell membrane abundance, an effect not mimicked by catalytically-inactive AMPKalphaK45R.

  2. NDPK-A (show NME1 Antibodies) exists in a functional cellular complex with AMPK (show PRKAA2 Antibodies) and CFTR (show CFTR Antibodies) in airway epithelia, and NDPK-A (show NME1 Antibodies) catalytic function is required for the AMPK (show PRKAA2 Antibodies)-dependent regulation of CFTR (show CFTR Antibodies)

Pig (Porcine) Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. Klotho (show KL Antibodies) gene deficiency promotes high-fat diet-induced fibrosis in aortic valves, likely through the AMPKalpha (show GRK4 Antibodies)-RUNX2 (show RUNX2 Antibodies) pathway.

  2. AMPK-mTOR (show FRAP1 Antibodies)-autophagy signaling is altered by intrauterine growth restriction in newborn piglets.

  3. Data indicate that 17beta-estradiol reduced Sertoli Cell proliferation by inhibiting microRNA miR (show MYLIP Antibodies)-1285 and thus activating AMP-activated protein kinase (AMPK (show PRKAA2 Antibodies)).

  4. L-Glutamine (show GFPT2 Antibodies) enhances enterocyte growth but did not affect abundances of total or phosphorylated AMPK protein.

  5. AMPK activity plays an important role in the maintenance of the spermatozoa quality during long-term storage of boar semen.

  6. AMPK, lying downstream of PKA, regulates at different levels mammalian spermatozoa membrane function.

  7. Porcine circovirus type 2 (PCV2) might induce autophagy via the AMPK/ERK (show MAPK1 Antibodies)/TSC2 (show TSC2 Antibodies)/mTOR (show FRAP1 Antibodies) signaling pathway in the host cells, representing a pivotal mechanism for PCV2 pathogenesis

  8. AMPK deficiency or inhibition attenuated or mitigated ethanol exposure-triggered glucose intolerance and compromised cardiac contraction by increased phosphorylation of AMPK and acetyl-CoA carboxylase as well as autophagosome accumulation.

  9. AMPK functions to inhibit IGF-I (show IGF1 Antibodies)-stimulated PI3K pathway activation through stimulation of IRS-1 (show IRS1 Antibodies) serine 794 phosphorylation.

  10. acute activation of AMPK increases intestinal glucose absorption after administration of long-chain n-3 polyunsaturated fatty acids during gestation

PRKAA1 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Alternative names and synonyms associated with PRKAA1

  • protein kinase, AMP-activated, alpha 3 catalytic subunit (Prkaa3) antibody
  • protein kinase, AMP-activated, alpha 1 catalytic subunit (PRKAA1) antibody
  • protein kinase, AMP-activated, alpha 1 catalytic subunit (prkaa1) antibody
  • protein kinase, AMP-activated, alpha 1 catalytic subunit (Prkaa1) antibody
  • AI194361 antibody
  • AI450832 antibody
  • AL024255 antibody
  • AMPK antibody
  • AMPK1 antibody
  • AMPKa1 antibody
  • AMPKalpha1 antibody
  • C130083N04Rik antibody
  • cb116 antibody
  • im:7154392 antibody
  • PRKAA1 antibody
  • sb:cb130 antibody
  • wu:fa94c10 antibody

Protein level used designations for PRKAA1

protein kinase, AMP-activated, alpha 3 catalytic subunit , protein kinase, AMP-activated, alpha 1 catalytic subunit , 5'-AMP-activated protein kinase catalyti subunit alpha-1-like protein , 5'-AMP-activated protein kinase catalytic subunit alpha-1 , AMPK-activated protein kinase alpha-1 subunit , 5'-AMP-activated protein kinase alpha 1 catalytic subunit , 5'-AMP-activated protein kinase, catalytic alpha-1 chain , ACACA kinase , AMP -activate kinase alpha 1 subunit , AMP-activated protein kinase, catalytic, alpha-1 , AMPK alpha 1 , AMPK subunit alpha-1 , HMGCR kinase , acetyl-CoA carboxylase kinase , hydroxymethylglutaryl-CoA reductase kinase , tau-protein kinase PRKAA1 , AMPK alpha-1 chain , AMP-activated protein kinase, alpha 1 catalytic subunit , ampka1 , 5'-AMP-activated protein kinase alpha-1 catalytic subunit , AMPKalpha1 , 63 kDa subunit , AMPK 63 kDa subunit

GENE ID SPECIES
108080 Mus musculus
100009710 Equus caballus
100034740 Meleagris gallopavo
100145520 Xenopus (Silurana) tropicalis
100294665 Ovis aries
540404 Bos taurus
5562 Homo sapiens
65248 Rattus norvegicus
105787 Mus musculus
100001198 Danio rerio
495290 Xenopus laevis
427185 Gallus gallus
479351 Canis lupus familiaris
100145903 Sus scrofa
100174304 Pongo abelii
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