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Browse our anti-PRKAA1 (PRKAA1) Antibodies

Full name:
anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit Antibodies (PRKAA1)
On www.antibodies-online.com are 303 Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) Antibodies from 29 different suppliers available. Additionally we are shipping PRKAA1 Kits (21) and PRKAA1 Proteins (6) and many more products for this protein. A total of 339 PRKAA1 products are currently listed.
Synonyms:
AI194361, AI450832, AL024255, AMPK, AMPK1, AMPKa1, AMPKalpha1, C130083N04Rik, cb116, im:7154392, PRKAA1, sb:cb130, wu:fa94c10
list all antibodies Gene Name GeneID UniProt
PRKAA1 108080  
PRKAA1 5562 Q13131
PRKAA1 65248 P54645

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Top referenced anti-PRKAA1 Antibodies

  1. Cow (Bovine) Polyclonal PRKAA1 Primary Antibody for ICC, IF - ABIN151706 : Zang, Zuccollo, Hou, Nagata, Walsh, Herscovitz, Brecher, Ruderman, Cohen: AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells. in The Journal of biological chemistry 2004 (PubMed)
    Show all 12 references for ABIN151706

  2. Human Monoclonal PRKAA1 Primary Antibody for IF, WB - ABIN393792 : Jassim, Fernø, Theisen, Haberhausen, Christoforou, Håvik, Gebhardt, Remschmidt, Mehler-Wex, Hebebrand, Lehellard, Steen: Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia. in Pharmacopsychiatry 2011 (PubMed)
    Show all 5 references for ABIN393792

  3. Human Polyclonal PRKAA1 Primary Antibody for IHC (p), WB - ABIN359481 : Pang, Xiong, Li, Qiu, Jin, Shen, Li: Conserved alpha-helix acts as autoinhibitory sequence in AMP-activated protein kinase alpha subunits. in The Journal of biological chemistry 2007 (PubMed)
    Show all 3 references for ABIN359481

  4. Human Polyclonal PRKAA1 Primary Antibody for EIA, WB - ABIN359393 : Zhang, Ye, Wu, Ren, Zhao, Zhao, Fu, Shen, Fan, Lu, Zhong, Xu, Han, Zhang, Tao, Huang, Zhou, Hu, Gu, Chen, Chen: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. in Genome research 2000 (PubMed)
    Show all 2 references for ABIN359393

  5. Human Polyclonal PRKAA1 Primary Antibody for IF, IHC (p) - ABIN196904 : Kim, Tannenbaum, White: Global phosphoproteome of HT-29 human colon adenocarcinoma cells. in Journal of proteome research 2005 (PubMed)
    Show all 2 references for ABIN196904

  6. Human Monoclonal PRKAA1 Primary Antibody for ELISA, FACS - ABIN4280435 : Xiao, Kwong, Daemen, Belvin, Liang, Hatzivassiliou, OBrien: Metabolic Response to NAD Depletion across Cell Lines Is Highly Variable. in PLoS ONE 2016 (PubMed)
    Show all 2 references for ABIN4280435

  7. Human Polyclonal PRKAA1 Primary Antibody for WB - ABIN2785614 : Hasumi, Baba, Hong, Hasumi, Huang, Yao, Valera, Linehan, Schmidt: Identification and characterization of a novel folliculin-interacting protein FNIP2. in Gene 2008 (PubMed)

  8. Human Polyclonal PRKAA1 Primary Antibody for FACS, IHC (p) - ABIN652306 : Puissant, Robert, Fenouille, Luciano, Cassuto, Raynaud, Auberger: Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation. in Cancer research 2010 (PubMed)

More Antibodies against PRKAA1 Interaction Partners

Mouse (Murine) Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. Ampkalpha1 promotes myocardial AP-1 (show JUN Antibodies) activation in a Pkczeta (show PRKCZ Antibodies)-dependent manner and thus contributes to cardiac stress signaling.

  2. gomisin N has a protective effect against hepatic steatosis through AMPK activation

  3. Loss of AMPKalpha1 is associated with impaired control of vesicular stomatitis virus infection.

  4. AMPK activation promotes retinal innate defense in endophthalmitis by modulating energy metabolism.

  5. Our findings further revealed that Sesn2 (show SESN2 Antibodies)-induced autophagy contributed to restore the impaired insulin (show INS Antibodies) signaling through the activation of AMPK signal. Even in the presence of palmitate, Sesn2 (show SESN2 Antibodies) up-regulation maintained insulin (show INS Antibodies) sensitivity and glucose metabolism via AMPK-dependent autophagic activation.

  6. FGF21 (show FGF21 Antibodies) promotes myoblast differentiation and serves as a switch of molecular transformation from anaerobic myofibers to aerobic myofibers via the FGF21 (show FGF21 Antibodies)-SIRT1 (show SIRT1 Antibodies)-AMPK-PGC1alpha axis.

  7. AMPKalpha1 mediates CHOP (show DDIT3 Antibodies) ubiquitination and proteasomal degradation in macrophages by promoting the phosphorylation of CHOP (show DDIT3 Antibodies) at serine 30. In a mouse model of plaque stability, deletion of Ampkalpha1 but not Ampkalpha2 (show PRKAA2 Antibodies) promoted injury-induced neointimal disruption.

  8. Taken together, these results suggest that exercise influences AMPKalpha2 (show PRKAA2 Antibodies) gene methylation in human blood and eminently in the skeletal muscle of mice and therefore might repress AMPKalpha2 (show PRKAA2 Antibodies) gene expression.

  9. Angiotensin-II up-regulates the Ampkalpha1 isoform in renal tissue. Ampkalpha1 participates in renal Tak1 (show NR2C2 Antibodies) activation and Tak1 (show NR2C2 Antibodies)-dependent signaling induced by angiotensin-II.

  10. AMPK activation stimulates oxidant-induced stress granule formation but limits their fusion into larger granules.

Cow (Bovine) Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. Endometrial inflammatory responses to lipopolysaccharide were also reduced by small molecules that activate or inhibit the intracellular sensor of energy, AMP-activated protein kinase (AMPK (show PRKAA2 Antibodies)).

  2. The results suggest that activation of AMPK represses global protein synthesis in mammary epithelial cells through inhibition of mTORC1 signaling.

  3. Nitrated oleic acid activates AMPK in endothelial cells.

  4. Findings suggest that ischemic factor stimulation of the blood brain barrier Na-K-Cl cotransporter (show SLC12A1 Antibodies) involves activation of AMPK.

  5. Results suggest that mitochondria-derived superoxide anions and peroxynitrite are required for Berberine-induced AMPK activation in endothelial cells.

  6. the expression, but not the kinase activity, of AMPK and CaMKKbeta is necessary for ADP signaling to eNOS (show NOS3 Antibodies)

Human Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. Thus, APC (show APC Antibodies) may be a potential novel therapeutic target for the management of diabetic cardiovascular complications such as diabetic cardiomyopathy.

  2. gomisin N has a protective effect against hepatic steatosis through AMPK activation

  3. Together, the results imply that targeted activation of AMPK by GSK621 inhibits melanoma cell survival and proliferation. MEK (show MAP2K1 Antibodies)-ERK (show EPHB2 Antibodies) inhibition may further sensitize GSK621's anti-melanoma cell activity in vitro and in vivo.

  4. AMP-activated protein kinase (AMPK (show PRKAA2 Antibodies)) is a fundamental regulator of energy metabolism, stress resistance, and cellular proteostasis

  5. FGF21 (show FGF21 Antibodies) protects against Ang II (show AGT Antibodies)-induced cerebrovascular aging via improving mitochondrial biogenesis and inhibiting p53 (show TP53 Antibodies) activation in an AMPK-dependent manner.

  6. Taken together, these results suggest that exercise influences AMPKalpha2 (show PRKAA2 Antibodies) gene methylation in human blood and eminently in the skeletal muscle of mice and therefore might repress AMPKalpha2 (show PRKAA2 Antibodies) gene expression.

  7. In summary, the results of the present study demonstrate mechanistic evidences that AMPK-independent programmed necrosis contributes to AICAR's cytotoxicity in prostate cancer cells.

  8. Inhibition of CK2 (show CSNK2A1 Antibodies) increased the expression of metabolic regulators, PDK4 (show PDK4 Antibodies) and AMPK along with the key cellular energy sensor CREB (show CREB1 Antibodies).

  9. AMPK activation stimulates oxidant-induced stress granule formation but limits their fusion into larger granules.

  10. ENO1 (show ENO1 Antibodies) is a potent promoter of colorectal cancer genesis and metastasis at least in part though regulating AMPK/mTOR (show FRAP1 Antibodies) pathway.

Zebrafish Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. AMPK-related pathways may be compromised during fluoxetine exposure as a result of increased miRNA abundance.

Xenopus laevis Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. Constitutively active AMPKgammaR70Q significantly decreases Napi-IIa (show SLC34A1 Antibodies) oocyte cell membrane abundance, an effect not mimicked by catalytically-inactive AMPKalphaK45R.

  2. NDPK-A (show NME1 Antibodies) exists in a functional cellular complex with AMPK (show PRKAA2 Antibodies) and CFTR (show CFTR Antibodies) in airway epithelia, and NDPK-A (show NME1 Antibodies) catalytic function is required for the AMPK (show PRKAA2 Antibodies)-dependent regulation of CFTR (show CFTR Antibodies)

Pig (Porcine) Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. AMPK-mTOR (show FRAP1 Antibodies)-autophagy signaling is altered by intrauterine growth restriction in newborn piglets.

  2. Data indicate that 17beta-estradiol reduced Sertoli Cell proliferation by inhibiting microRNA miR (show MYLIP Antibodies)-1285 and thus activating AMP-activated protein kinase (AMPK (show PRKAA2 Antibodies)).

  3. L-Glutamine (show GFPT2 Antibodies) enhances enterocyte growth but did not affect abundances of total or phosphorylated AMPK protein.

  4. AMPK activity plays an important role in the maintenance of the spermatozoa quality during long-term storage of boar semen.

  5. AMPK, lying downstream of PKA, regulates at different levels mammalian spermatozoa membrane function.

  6. Porcine circovirus type 2 (PCV2) might induce autophagy via the AMPK/ERK (show MAPK1 Antibodies)/TSC2 (show TSC2 Antibodies)/mTOR (show FRAP1 Antibodies) signaling pathway in the host cells, representing a pivotal mechanism for PCV2 pathogenesis

  7. AMPK deficiency or inhibition attenuated or mitigated ethanol exposure-triggered glucose intolerance and compromised cardiac contraction by increased phosphorylation of AMPK and acetyl-CoA carboxylase as well as autophagosome accumulation.

  8. AMPK functions to inhibit IGF-I (show IGF1 Antibodies)-stimulated PI3K pathway activation through stimulation of IRS-1 (show IRS1 Antibodies) serine 794 phosphorylation.

  9. acute activation of AMPK increases intestinal glucose absorption after administration of long-chain n-3 polyunsaturated fatty acids during gestation

PRKAA1 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Alternative names and synonyms associated with PRKAA1

  • protein kinase, AMP-activated, alpha 3 catalytic subunit (Prkaa3) antibody
  • protein kinase, AMP-activated, alpha 1 catalytic subunit (PRKAA1) antibody
  • protein kinase, AMP-activated, alpha 1 catalytic subunit (prkaa1) antibody
  • protein kinase, AMP-activated, alpha 1 catalytic subunit (Prkaa1) antibody
  • AI194361 antibody
  • AI450832 antibody
  • AL024255 antibody
  • AMPK antibody
  • AMPK1 antibody
  • AMPKa1 antibody
  • AMPKalpha1 antibody
  • C130083N04Rik antibody
  • cb116 antibody
  • im:7154392 antibody
  • PRKAA1 antibody
  • sb:cb130 antibody
  • wu:fa94c10 antibody

Protein level used designations for PRKAA1

protein kinase, AMP-activated, alpha 3 catalytic subunit , protein kinase, AMP-activated, alpha 1 catalytic subunit , 5'-AMP-activated protein kinase catalyti subunit alpha-1-like protein , 5'-AMP-activated protein kinase catalytic subunit alpha-1 , AMPK-activated protein kinase alpha-1 subunit , 5'-AMP-activated protein kinase alpha 1 catalytic subunit , 5'-AMP-activated protein kinase, catalytic alpha-1 chain , ACACA kinase , AMP -activate kinase alpha 1 subunit , AMP-activated protein kinase, catalytic, alpha-1 , AMPK alpha 1 , AMPK subunit alpha-1 , HMGCR kinase , acetyl-CoA carboxylase kinase , hydroxymethylglutaryl-CoA reductase kinase , tau-protein kinase PRKAA1 , AMPK alpha-1 chain , AMP-activated protein kinase, alpha 1 catalytic subunit , ampka1 , 5'-AMP-activated protein kinase alpha-1 catalytic subunit , AMPKalpha1 , 63 kDa subunit , AMPK 63 kDa subunit

GENE ID SPECIES
108080 Mus musculus
100009710 Equus caballus
100034740 Meleagris gallopavo
100145520 Xenopus (Silurana) tropicalis
100294665 Ovis aries
540404 Bos taurus
5562 Homo sapiens
65248 Rattus norvegicus
105787 Mus musculus
100001198 Danio rerio
495290 Xenopus laevis
427185 Gallus gallus
479351 Canis lupus familiaris
100145903 Sus scrofa
100174304 Pongo abelii
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