Microtubule Star antibody (MTS) (C-Term)

Details for Product anti-MTS Antibody No. ABIN1042659, Supplier: Log in to see
Antigen
  • AI115466
  • D8Ertd766e
  • PP2Ac
  • PP2CA
  • PP2Calpha
  • RP-C
  • protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
  • protein phosphatase 2, catalytic subunit, alpha isozyme
  • Ppp2cb
  • PPP2CA
Alternatives
anti-Mouse (Murine) Microtubule Star antibody for Western Blotting
Epitope
C-Term
1
1
Reactivity
Mouse (Murine), Rat (Rattus), Human
3
2
2
Host
Mouse
2
1
Clonality (Clone)
Monoclonal ()
Application
Immunoprecipitation (IP), Western Blotting (WB)
3
2
2
1
1
Options
Supplier
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Immunogen A KLH-coupled peptide with the sequence: KLH-C-AYA-RRTPDYFL-OMe. The c-terminal sequence (as well as the carboxy-methylation) is absolutely conserved from human, mouse to yeast
Sequence KLH-C-ßA-RRTPDYFL-OMe
Clone 2A10
Isotype IgG1
Specificity Recognises specifically the C-terminally methylated form of PP2A C subunit
Cross-Reactivity Yeast (Saccharomyces cerevisiae)
Cross-Reactivity (Details) Mouse, Rat, Human.Predicted to work with: Saccharomyces cerevisiae
Purification Protein G
Alternative Name PP2A C (MTS Antibody Abstract)
Background Synonyms:
PP2A alpha antibody,PP2A C antibody,PP2A-alpha antibody,PP2AA_HUMAN antibody,PP2Ac antibody,PP2CA antibody,PPP2CA antibody,Protein phosphatase 2, catalytic subunit, alpha isoform antibody,Replication protein C antibody
Gene ID 5515, 19052, 24672
OMIM 176915
UniProt P63331
Pathways PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades
Application Notes Optimal antibody dilution should be determined by titration, however as a guideline try, WB: 1,500. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa)
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Purified antibody (from supernatant) containing PBS + 0.1 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
 image for anti-Microtubule Star (MTS) (C-Term) antibody (ABIN1042659) anti-Microtubule Star (MTS) (C-Term) antibody
 image for anti-Microtubule Star (MTS) (C-Term) antibody (ABIN1042659) anti-Microtubule Star (MTS) (C-Term) antibody (Image 2)
Product cited in: Benziane, Björnholm, Pirkmajer, Austin, Kotova, Viollet, Zierath, Chibalin: "Activation of AMP-activated protein kinase stimulates Na+,K+-ATPase activity in skeletal muscle cells." in: The Journal of biological chemistry, Vol. 287, Issue 28, pp. 23451-63, 2012 (PubMed).

Li, Huang, Liang, Fu, Guo, Xu: "Microcystin-LR (MCLR) induces a compensation of PP2A activity mediated by α4 protein in HEK293 cells." in: International journal of biological sciences, Vol. 7, Issue 6, pp. 740-52, 2011 (PubMed).

Finnegan, Mackey, Cotter: "A stress survival response in retinal cells mediated through inhibition of the serine/threonine phosphatase PP2A." in: The European journal of neuroscience, Vol. 32, Issue 3, pp. 322-34, 2010 (PubMed).

Hombauer, Weismann, Mudrak, Stanzel, Fellner, Lackner, Ogris: "Generation of active protein phosphatase 2A is coupled to holoenzyme assembly." in: PLoS biology, Vol. 5, Issue 6, pp. e155, 2007 (PubMed).

Sontag, Nunbhakdi-Craig, Sontag, Diaz-Arrastia, Ogris, Dayal, Lentz, Arning, Bottiglieri: "Protein phosphatase 2A methyltransferase links homocysteine metabolism with tau and amyloid precursor protein regulation." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 11, pp. 2751-9, 2007 (PubMed).

Sontag, Hladik, Montgomery, Luangpirom, Mudrak, Ogris, White: "Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis." in: Journal of neuropathology and experimental neurology, Vol. 63, Issue 10, pp. 1080-91, 2004 (PubMed).

Sontag, Luangpirom, Hladik, Mudrak, Ogris, Speciale, White: "Altered expression levels of the protein phosphatase 2A ABalphaC enzyme are associated with Alzheimer disease pathology." in: Journal of neuropathology and experimental neurology, Vol. 63, Issue 4, pp. 287-301, 2004 (PubMed).

Fellner, Lackner, Hombauer, Piribauer, Mudrak, Zaragoza, Juno, Ogris: "A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo." in: Genes & development, Vol. 17, Issue 17, pp. 2138-50, 2003 (PubMed).

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