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Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) antibody

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Synonyms AA408410, AI256620, AL024194, AL024437, AW557595, C86794, Hnrpu, SAFA, Sp120, hnRNP U, SN1, HNRPU, SAF-A, U21.1, saf-a
Mouse (Murine), Human, Monkey
(53), (27), (26), (3), (2), (2), (1), (1), (1), (1)
(38), (15)
Clonality (Clone)
Monoclonal ()
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
ELISA, Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
(41), (14), (11), (10), (8), (7), (6), (3), (1), (1)
Pubmed 8 references available
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Quantity 0.1 mL
Shipping to United States ( )
Availability Will be delivered in 5 to 6 Business Days
Immunogen RNPs eluted from an oligo (dt) cellulose column
Clone 3G6
Isotype IgG1
No Cross-Reactivity Chicken, Lizard
Cross-Reactivity (Details) Does not react with Chicken,Lizard
Characteristics Myeloma fusion partners:
Detects a band of approximately 97 kDa (predicted molecular weight: 120 kDa).
Purification Protein A
Alternative Name hnRNP U (HNRNPU Antibody Abstract)
Background Synonyms:
Heterogeneous nuclear ribonucleoprotein U antibody,hnRNP U protein antibody,HNRNPU antibody,hnRNPUprotein antibody,HNRPU antibody,p120 antibody,p120 nuclear protein antibody,pp120 antibody,SAF Aantibody,SAF-A antibody,SAFA antibody,Scaffold attachment factor A antibody,U21.1antibody
UniProt Q8VEK3
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Optimal antibody dilution should be determined by titration, however as a guideline try, WB: Use at an assay dependent dilution. ICC/IFICC/IF: 1/100. Flow CytFlow Cyt: Use 1µg for 106 cells.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS, 0.1 % sodium azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Storage 4 °C
Supplier Images
Western Blotting (WB) image for anti-Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) antibody (ABIN108577) Western blot of anti-hnRNP-U on HeLa cell extract
Product cited in: Pare, López-Orozco, Hobman: "MicroRNA-binding is required for recruitment of human Argonaute 2 to stress granules and P-bodies." in: Biochemical and biophysical research communications, Vol. 414, Issue 1, pp. 259-64, 2011 (PubMed).

Tserel, Runnel, Kisand et al.: "MicroRNA expression profiles of human blood monocyte-derived dendritic cells and macrophages reveal miR-511 as putative positive regulator of Toll-like receptor 4." in: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26487-95, 2011 (PubMed).

Raju, Fukuda, López-Iglesias et al.: "In neurons, activity-dependent association of dendritically transported mRNA transcripts with the transacting factor CBF-A is mediated by A2RE/RTS elements." in: Molecular biology of the cell, Vol. 22, Issue 11, pp. 1864-77, 2011 (PubMed).

Ma, Matsunaga, Morimoto et al.: "The nuclear scaffold protein SAF-A is required for kinetochore-microtubule attachment and contributes to the targeting of Aurora-A to mitotic spindles." in: Journal of cell science, Vol. 124, Issue Pt 3, pp. 394-404, 2011 (PubMed).

Hadian, Vincendeau, Mäusbacher et al.: "Identification of a heterogeneous nuclear ribonucleoprotein-recognition region in the HIV Rev protein." in: The Journal of biological chemistry, Vol. 284, Issue 48, pp. 33384-91, 2009 (PubMed).

Uchimura, Ichimura, Uwada et al.: "Involvement of SUMO modification in MBD1- and MCAF1-mediated heterochromatin formation." in: The Journal of biological chemistry, Vol. 281, Issue 32, pp. 23180-90, 2006 (PubMed).

Ahmad, Lingrel: "Kruppel-like factor 2 transcriptional regulation involves heterogeneous nuclear ribonucleoproteins and acetyltransferases." in: Biochemistry, Vol. 44, Issue 16, pp. 6276-85, 2005 (PubMed).

Dreyfuss, Choi, Adam: "Characterization of heterogeneous nuclear RNA-protein complexes in vivo with monoclonal antibodies." in: Molecular and cellular biology, Vol. 4, Issue 6, pp. 1104-14, 1984 (PubMed).

Catalog No. ABIN108577
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