Apoptotic Chromatin Condensation Inducer 1 (ACIN1) (N-Term), (AA 1-523), (N-Term) antibody

Details for Product No. ABIN1105223
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Antigen
Synonyms
ACINUS, ACN, fSAP152, Acn, Acinus, C79325, acinusL, acinusS, mKIAA0670, 2610036I19Rik, 2610510L13Rik, acinus, acinusb, fi14c05, wu:fe06a10, wu:fi14c05, acinusa, acinusl, wu:fb04g06, wu:fb40f03, wu:fb6 ... show more
ACINUS, ACN, fSAP152, Acn, Acinus, C79325, acinusL, acinusS, mKIAA0670, 2610036I19Rik, 2610510L13Rik, acinus, acinusb, fi14c05, wu:fe06a10, wu:fi14c05, acinusa, acinusl, wu:fb04g06, wu:fb40f03, wu:fb68h03, wu:fb80f07, wu:fc12e10, ik:tdsubc_2g5, si:zc14a17.12, xx:tdsubc_2g5, acn show less
Epitope
N-Term, AA 1-523, N-Term
(32), (16), (12), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(130), (41), (26), (24), (24), (12)
Host
Mouse
(130), (5)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Immunoprecipitation (IP), Western Blotting (WB)
(113), (47), (35), (20), (12), (11), (7), (2), (2), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN1105223
Quantity 0.1 mg
Price
368.50 $   Plus shipping costs $45.00
Shipping to United States (Change)
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen GST-human AcinusL fusion protein corresponding to N-terminal amino acids (1~523 a.a.)
Clone 3H8
Isotype IgG1
Specificity This antibody reacts withAcinusL.
Purification Protein A agarose beads
Alternative Name Acinus / ACIN1
Background Chromatin condensation and nuclear fragmentation (CCNF) are hallmarks of apoptosis. CCNF is triggered by the activation of members of the caspase family, caspase-activated DNase (CAD/DFF40) and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (Apoptotic Chromatin Condensation Inducer in the Nucleus). The 220 kDa Acinus protein is cleaved by caspase-3 and an additional unknown protease to generate a 17 kDa peptide that which causes chromatin condensation in vitro when added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS, and AcinusS'. Acinus is ubiquitously expressed.
Alternate names: Apoptotic chromatin condensation inducer in the nucleus, KIAA0670
Gene ID 22985
NCBI Accession NP_001158286.1
UniProt Q9UKV3
Research Area Cell Cycle, Apoptosis/Necrosis
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS containing 50% glycerol, pH 7.2. Contains no preservatives.
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store (in aliquots) at -20 °C.
Expiry Date 12 months
Supplier Images
anti-Apoptotic Chromatin Condensation Inducer 1 (ACIN1) (N-Term), (AA 1-523), (N-Term) antibody anti-Apoptotic Chromatin Condensation Inducer 1 (ACIN1) (N-Term), (AA 1-523), (N-Term) antibody
anti-Apoptotic Chromatin Condensation Inducer 1 (ACIN1) (N-Term), (AA 1-523), (N-Term) antibody (2) anti-Apoptotic Chromatin Condensation Inducer 1 (ACIN1) (N-Term), (AA 1-523), (N-Term) antibody (Image 2)
Background publications Sahara, Aoto, Eguchi et al.: "Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation." in: Nature, Vol. 401, Issue 6749, pp. 168-73, 1999 (PubMed).

Hosts (130), (5)
Reactivities (130), (41), (26), (24), (24), (12)
Applications (113), (47), (35), (20), (12), (11), (7), (2), (2), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (32), (16), (12), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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