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Details for Product No. ABIN1106473

Neural Cell Adhesion Molecule 1 (NCAM1) antibody

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Antigen
Synonyms CD56, NCAM, MSK39, E-NCAM, NCAM-1, Ncam, Cd56, N-CAM, N-CAM-1, NCAM-C, NCAMC, fj56g09, ncam, ncam1, wu:fj56g09, NCAM1, n-cam
Reactivity
»Alternatives Human, Rat (Rattus)
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN1106473
Quantity 0.1 mg
Price
297.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Growth cone enriched plasma membrane fraction from E17 Rat forebrain
Clone IML-43
Isotype IgG1
Specificity This antibody recognizes NCAM/CD56. No cross reactivity with other proteins.
Purification Affinity Chromatography
Alternative Name CD56
Background The neural cell adhesion molecule appears on early embryonic cells and is important in the formation of cell collectives and their boundaries at sites of morphogenesis. Later in development it is found on various differentiated tissues and is a major CAM mediating adhesion among neurons and between neurons and muscle. NCAM shares many features with immunoglobulins and is considered a member of the immunoglobulin superfamily NCAM gene is mapped to 11q23.1.
Alternate names: N-CAM-1, NCAM, NCAM-1, Neural cell adhesion molecule 1
Gene ID 24586
NCBI Accession NP_113709
UniProt P13596
Research Area CD Antigens, Surface Receptors of Immune Cells, Signaling
Restrictions For Research Use only
Reconstitution Restore with 1.2% Sodium Acetate or neutral PBS
Concentration 0.1 mg/mL (after reconstitution with PBS)
Buffer 1.2 % Sodium Acetate 0.01 mg Sodium Azide 2 mg BSA
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Cunningham, Hemperly, Murray et al.: "Neural cell adhesion molecule: structure, immunoglobulin-like domains, cell surface modulation, and alternative RNA splicing." in: Science (New York, N.Y.), Vol. 236, Issue 4803, pp. 799-806, 1987 (PubMed).

DEustachio, Owens, Edelman et al.: "Chromosomal location of the gene encoding the neural cell adhesion molecule (N-CAM) in the mouse." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 82, Issue 22, pp. 7631-5, 1985 (PubMed).

Alternatives for antigen "Neural Cell Adhesion Molecule 1 (NCAM1)", type "Antibodies"
Hosts (302), (71), (4), (2), (1), (1)
Reactivities (350), (65), (60), (41), (41), (36), (36), (19), (17), (3), (2), (1), (1), (1)
Applications (220), (106), (95), (55), (49), (35), (35), (33), (27), (22), (20), (6), (5), (3), (1), (1), (1), (1)
Conjugates (29), (29), (27), (11), (7), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Epitopes (7), (4), (3), (3), (2), (2), (2), (2), (2), (1)
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