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CD56 antibody (Neural Cell Adhesion Molecule 1)

Details for Product anti-NCAM1 Antibody No. ABIN1106473, Supplier: Log in to see
Antigen
  • NCAM1
  • ncam
  • n-cam
  • CD56
  • MSK39
  • NCAM
  • E-NCAM
  • NCAM-1
  • Ncam
  • Cd56
  • N-CAM
  • N-CAM-1
  • NCAM-C
  • NCAMC
  • fj56g09
  • ncam1
  • wu:fj56g09
Reactivity
Human, Rat (Rattus)
592
94
71
15
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7
4
4
3
3
3
3
2
1
Host
Mouse
511
99
15
11
1
1
Clonality (Clone)
Monoclonal ()
Conjugate
This CD56 antibody is un-conjugated
58
51
38
26
9
8
8
7
7
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6
5
5
5
5
4
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
339
235
123
114
90
75
74
55
23
22
7
6
5
4
4
3
3
2
2
2
2
2
1
1
1
1
Supplier
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Immunogen Growth cone enriched plasma membrane fraction from E17 Rat forebrain
Clone IML-43
Isotype IgG1
Specificity This antibody recognizes NCAM/CD56. No cross reactivity with other proteins.
Purification Affinity Chromatography
Alternative Name CD56 (NCAM1 Antibody Abstract)
Background The neural cell adhesion molecule appears on early embryonic cells and is important in the formation of cell collectives and their boundaries at sites of morphogenesis. Later in development it is found on various differentiated tissues and is a major CAM mediating adhesion among neurons and between neurons and muscle. NCAM shares many features with immunoglobulins and is considered a member of the immunoglobulin superfamily NCAM gene is mapped to 11q23.1.Synonyms: N-CAM-1, NCAM, NCAM-1, Neural cell adhesion molecule 1
Gene ID 24586
NCBI Accession NP_113709
UniProt P13596
Research Area CD Antigens, Surface Receptors of Immune Cells, Signaling
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Reconstitution Restore with 1.2 % Sodium Acetate or neutral PBS
Concentration 0.1 mg/mL (after reconstitution with PBS)
Buffer 1.2 % Sodium Acetate, 0.01 mg Sodium Azide, 2 mg BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications DEustachio, Owens, Edelman et al.: "Chromosomal location of the gene encoding the neural cell adhesion molecule (N-CAM) in the mouse." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 82, Issue 22, pp. 7631-5, 1985 (PubMed).

Cunningham, Hemperly, Murray et al.: "Neural cell adhesion molecule: structure, immunoglobulin-like domains, cell surface modulation, and alternative RNA splicing." in: Science (New York, N.Y.), Vol. 236, Issue 4803, pp. 799-806, 1987 (PubMed).